Harmony Biosciences Holdings, Inc.

HRMY • NASDAQ

Harmony Biosciences Holdings, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Dr. Jeffrey M. Dayno, with a market cap of $2.3B. As of Q3 2025, 82% of shares are held by 290 institutional investors, with BlackRock, Inc. as the largest holder at 12.04%.

President and Chief Executive OfficerDr. Jeffrey M. Dayno

Market Cap$2.3B

Biotechnology

Healthcare

Employees246.0

Websiteharmonybiosciences.com

Country

United States of America

Overview

Overview of institutional ownership in HRMY as of Q3 2025 with a market cap of $1.6B

All Institutions

Institutions: 290
Value Held: $1.3B
Shares Held: 47.3M
Avg Position: $4.5M
Median Position: $511.8K

Hedge Funds

Hedge Funds: 35
Value Held: $141.5M
Shares Held: 5.1M
Avg Position: $4.0M
Median Position: $922.3K

Ownership Breakdown

Institutional (non-HF)

73.13%

$1.2B

Hedge Funds

8.93%

$141.5M

Retail & Other

17.95%

$284.6M

Based on market cap of $1.6B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in HRMY as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$190.9M 0.00% of portfolio	12.04% 6.9M shares	Q3 2020 Held for 5y 2m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$140.5M 0.00% of portfolio	8.86% 5.1M shares	Q4 2020 Held for 4y 11m	$6.69T
FMR LLC Institution	-	$106.0M 0.01% of portfolio	6.69% 3.8M shares	Q3 2020 Held for 5y 2m	$1.92T
DIMENSIONAL FUND ADVISORS LP Long Only Manager	David Paul Butler CEO	$46.6M 0.01% of portfolio	2.94% 1.7M shares	Q3 2021 Held for 4y 2m	$466.32B
A AMERICAN CENTURY COMPANIES INC Institution	-	$46.0M 0.02% of portfolio	2.90% 1.7M shares	Q3 2020 Held for 5y 2m	$195.93B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$45.6M 0.00% of portfolio	2.87% 1.7M shares	Q4 2020 Held for 4y 11m	$2.88T
L LSV ASSET MANAGEMENT Long Only Manager	Josef Nmn Lakonishok CEO	$44.0M 0.10% of portfolio	2.77% 1.6M shares	Q4 2023 Held for 1y 11m	$45.1B
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	Anthony Ryan CEO	$35.7M 0.02% of portfolio	2.25% 1.3M shares	Q3 2024 Held for 1y 2m	$158.92B
Valor Management LLC RIA/Wealth	Francisco Ivan Narvaez CEO	$35.0M 51.91% of portfolio	2.20% 1.3M shares	Q4 2021 Held for 3y 11m	$67.3M
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$34.7M 0.00% of portfolio	2.19% 1.3M shares	Q3 2020 Held for 5y 2m	$1.57T

Net Capital Flow

Institutional buying and selling activity for HRMY in Q3 2025

Traded: −$101.2M
Buyers: 158
Sellers: 109
Total Bought: +$146.6M
Total Sold: −$247.7M
Avg Position: $4.1M

Biggest Buyers

Institution	Net Bought	Current Position
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	+$10.7M +388.5K shares	$35.7M 1.3M shares
UBS Group AG Institution	+$9.4M +342.5K shares	$13.9M 503.1K shares
D DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main Institution	+$7.2M +261.9K shares	$7.3M 265.7K shares
Bridgewater Associates, LP Hedge Fund•Global Macro	+$5.8M +211.5K shares	$5.8M 211.5K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	+$5.7M +207.6K shares	$31.3M 1.1M shares
GEODE CAPITAL MANAGEMENT LLC ETF Provider	+$5.6M +203.9K shares	$34.7M 1.3M shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$5.6M +203.5K shares	$9.8M 355.6K shares
$DEUTSCHE BANK AG\ logo$ DEUTSCHE BANK AG\ Institution	+$5.5M +200.5K shares	$11.7M 425.7K shares
B BlackRock, Inc. Institution	+$5.2M +189.0K shares	$190.9M 6.9M shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$4.8M +175.2K shares	$5.6M 204.5K shares

Biggest Sellers

Institution	Net Sold	Current Position
Valor Management LLC RIA/Wealth	−$147.4M −5.3M shares	$35.0M 1.3M shares
Marshall Wace LLP Institution	−$25.5M −924.2K shares	$7.9M 285.3K shares
FMR LLC Institution	−$23.2M −841.2K shares	$106.0M 3.8M shares
M MACQUARIE GROUP LTD Institution	−$4.0M −127.3K shares	Sold Off 0 shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	−$3.7M −116.2K shares	Sold Off 0 shares
R Ruffer LLP Long Only Manager	−$2.7M −86.2K shares	Sold Off 0 shares
A AXA Institution	−$2.6M −82.9K shares	Sold Off 0 shares
PRUDENTIAL FINANCIAL INC Institution	−$2.6M −93.4K shares	$1.6M 58.2K shares
R RICE HALL JAMES & ASSOCIATES, LLC Long Only Manager	−$2.4M −76.3K shares	Sold Off 0 shares
BANK OF AMERICA CORP /DE/ Institution	−$2.2M −79.8K shares	$5.2M 190.4K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited HRMY in Q3 2025

New Positions: 26
New Value: $22.1M
Exited Positions: 24
Exited Value: $23.5M

New Positions

Institution	Position Value
Bridgewater Associates, LP Hedge Fund•Global Macro	$5.8M 211.5K shares
Brandywine Global Investment Management, LLC Long Only Manager	$4.0M 146.2K shares
Zuckerman Investment Group, LLC RIA/Wealth	$3.4M 123.3K shares
S State of New Jersey Common Pension Fund D Institution	$1.6M 57.0K shares
O OSSIAM Institution	$1.5M 55.5K shares
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$1.4M 50.0K shares
F Freestone Grove Partners LP Hedge Fund•Multi-Strategy	$714.4K 25.9K shares
C CAXTON ASSOCIATES LLP Institution	$453.4K 16.5K shares
HPM Partners LLC RIA/Wealth	$442.5K 16.1K shares
B BLAIR WILLIAM & CO/IL Institution	$393.9K 14.3K shares

Exited Positions

Institution	Previous Position
M MACQUARIE GROUP LTD Institution	$4.0M 127.3K shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	$3.7M 116.2K shares
R Ruffer LLP Long Only Manager	$2.7M 86.2K shares
A AXA Institution	$2.6M 82.9K shares
R RICE HALL JAMES & ASSOCIATES, LLC Long Only Manager	$2.4M 76.3K shares
Weiss Asset Management LP Hedge Fund•Multi-Strategy	$1.8M 58.1K shares
T TEXAS PERMANENT SCHOOL FUND Institution	$1.1M 34.7K shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	$1.1M 33.8K shares
SUNRISE PARTNERS LIMITED PARTNERSHIP /CT Hedge Fund•Multi-Strategy	$935.9K 29.6K shares
Q Qube Research & Technologies Ltd Institution	$797.3K 25.2K shares

Options Activity

Institutions with the largest Call and Put options positions in HRMY as of Q3 2025

Call Positions: 9
Call Value: $29.0M
Put Positions: 5
Put Value: $8.5M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$8.8M 3.2K contracts
Caption Management, LLC Hedge Fund•Long/Short	$7.9M 2.9K contracts
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$4.1M 1.5K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$2.8M 1.0K contracts
G GREAT POINT PARTNERS LLC Private Equity	$2.3M 850.0 contracts
J JANE STREET GROUP, LLC Institution	$1.4M 520.0 contracts
J J. Goldman & Co LP Hedge Fund•Multi-Strategy	$760.7K 276.0 contracts
N NOMURA HOLDINGS INC Institution	$578.8K 210.0 contracts
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	$278.4K 101.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$4.1M 1.5K contracts
J JANE STREET GROUP, LLC Institution	$1.7M 624.0 contracts
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$1.4M 501.0 contracts
Caption Management, LLC Hedge Fund•Long/Short	$730.3K 265.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$633.9K 230.0 contracts

Most Committed Institutions

Institutions with HRMY as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Valor Management LLC RIA/Wealth	Francisco Ivan Narvaez CEO	51.91% $35.0M	2.20% 1.3M shares	Q4 2021 Held for 3y 11m	$67.3M
V venBio Partners LLC Institution	-	7.64% $13.5M	0.85% 489.2K shares	Q3 2020 Held for 5y 2m	$176.4M
T Tieton Capital Management, LLC Long Only Manager	William Joseph Dezellem President	2.86% $8.2M	0.52% 298.6K shares	Q2 2025 Held for 5 months	$288.1M
Bridge City Capital, LLC Long Only Manager	Alexander Jackson Woodward President	1.91% $7.2M	0.45% 259.9K shares	Q3 2024 Held for 1y 2m	$374.5M
CAPITAL MANAGEMENT CORP /VA RIA/Wealth	Pamela Catherine Simms President	1.40% $8.9M	0.56% 322.9K shares	Q1 2024 Held for 1y 8m	$636.3M
N Nan Fung Group Holdings Ltd Institution	-	1.37% $745.5K	0.05% 27.0K shares	Q2 2021 Held for 4y 5m	$54.3M
H HealthInvest Partners AB Institution	-	1.05% $269.4K	0.16% 92.1K shares	Q4 2023 Held for 1y 11m	$25.6M
Q Quantedge Capital Pte Ltd Institution	-	0.98% $1.8M	0.11% 64.7K shares	Q3 2025 Held for 2 months	$182.7M
DIADEMA PARTNERS LP Hedge Fund•Long/Short	Timothy Beau Bassett CIO	0.96% $1.4M	0.09% 50.0K shares	Q3 2025 Held for 2 months	$143.3M
Aurora Investment Counsel RIA/Wealth	David John Yucius President	0.93% $1.8M	0.11% 63.6K shares	Q4 2024 Held for 11 months	$188.5M

Hedge Fund Spotlight

Discover hedge funds investing in HRMY

Trexquant Investment LP

Hedge Fund • Quant

Portfolio ManagerTaesoon (Tyger) Park

Portfolio Value: $9.7B
Positions: 1,540
Last Reported: Q3 2025

Sector Allocation

Position in Harmony Biosciences Holdings, Inc.

Market Value: $7.5M
Shares Held: 272.0K
Portfolio Weight: 0.08%
Owned Since: 2024-Q4

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