Arcus Biosciences

RCUS • NYSE

Arcus Biosciences is a biotechnology company in the healthcare sector on NYSE, led by Terry Rosen, with a market cap of $2.7B. As of Q3 2025, 94% of shares are held by 183 institutional investors, with GILEAD SCIENCES, INC. as the largest holder at 29.53%.

CEOTerry Rosen

Market Cap$2.7B

Biotechnology

Healthcare

Employees577.0

Websitearcusbio.com

Country

United States of America

Overview

Overview of institutional ownership in RCUS as of Q3 2025 with a market cap of $1.4B

All Institutions

Institutions: 183
Value Held: $1.4B
Shares Held: 100.4M
Avg Position: $7.5M
Median Position: $483.7K

Hedge Funds

Hedge Funds: 28
Value Held: $257.6M
Shares Held: 18.9M
Avg Position: $9.2M
Median Position: $3.3M

Ownership Breakdown

Institutional (non-HF)

76.49%

$1.1B

Hedge Funds

17.79%

$257.6M

Retail & Other

5.71%

$82.7M

Based on market cap of $1.4B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in RCUS as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
GILEAD SCIENCES, INC. Institution	Daniel O'Day CEO	$427.4M 23.86% of portfolio	29.53% 31.4M shares	Q4 2024 Held for 11 months	$1.8B
B BlackRock, Inc. Institution	-	$160.6M 0.00% of portfolio	11.10% 11.8M shares	Q1 2018 Held for 7y 8m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$90.2M 0.00% of portfolio	6.23% 6.6M shares	Q1 2018 Held for 7y 8m	$6.69T
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	Steven Alan Cohen CEO	$58.9M 0.14% of portfolio	4.07% 4.3M shares	Q3 2022 Held for 3y 2m	$43.2B
Woodline Partners LP Hedge Fund•Long/Short	Karl Heinz Kroeker CIO	$51.3M 0.24% of portfolio	3.54% 3.8M shares	Q4 2022 Held for 2y 11m	$21.3B
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	$50.2M 1.52% of portfolio	3.47% 3.7M shares	Q3 2023 Held for 2y 2m	$3.3B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$46.2M 0.00% of portfolio	3.19% 3.4M shares	Q2 2018 Held for 7y 5m	$2.88T
S Siren, L.L.C. Institution	-	$39.6M 1.66% of portfolio	2.74% 2.9M shares	Q3 2024 Held for 1y 2m	$2.4B
FMR LLC Institution	-	$31.2M 0.00% of portfolio	2.16% 2.3M shares	Q1 2020 Held for 5y 8m	$1.92T
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$21.7M 0.00% of portfolio	1.50% 1.6M shares	Q2 2018 Held for 7y 5m	$1.57T

Net Capital Flow

Institutional buying and selling activity for RCUS in Q3 2025

Traded: +$21.5M
Buyers: 95
Sellers: 82
Total Bought: +$99.2M
Total Sold: −$77.7M
Avg Position: $6.5M

Biggest Buyers

Institution	Net Bought	Current Position
S Siren, L.L.C. Institution	+$17.7M +1.3M shares	$39.6M 2.9M shares
BANK OF AMERICA CORP /DE/ Institution	+$11.7M +863.2K shares	$18.5M 1.4M shares
F Fisher Asset Management, LLC Institution	+$8.7M +641.0K shares	$9.9M 729.2K shares
Decheng Capital LLC Venture Capital	+$5.3M +387.6K shares	$7.4M 547.6K shares
Candriam Luxembourg S.C.A. Long Only Manager	+$5.1M +378.4K shares	$5.1M 378.4K shares
B BlackRock, Inc. Institution	+$4.8M +352.9K shares	$160.6M 11.8M shares
WELLINGTON MANAGEMENT CO LLP Long Only Manager	+$4.5M +330.3K shares	$17.2M 1.3M shares
S Standard Life Aberdeen plc Institution	+$4.4M +331.7K shares	$4.4M 331.7K shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	+$4.3M +314.8K shares	$15.2M 1.1M shares
GOLDMAN SACHS GROUP INC Institution	+$4.1M +302.5K shares	$12.9M 950.6K shares

Biggest Sellers

Institution	Net Sold	Current Position
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$22.2M −1.6M shares	$58.9M 4.3M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$4.3M −316.1K shares	$4.0M 295.1K shares
FMR LLC Institution	−$3.8M −277.3K shares	$31.2M 2.3M shares
J JANE STREET GROUP, LLC Institution	−$3.5M −256.5K shares	$3.1M 225.6K shares
STATE STREET CORP Institution	−$3.2M −236.0K shares	$46.2M 3.4M shares
Woodline Partners LP Hedge Fund•Long/Short	−$3.1M −230.3K shares	$51.3M 3.8M shares
Trexquant Investment LP Hedge Fund•Quant	−$2.9M −211.3K shares	$647.3K 47.6K shares
CITIGROUP INC Institution	−$2.6M −192.5K shares	$500.0K 36.8K shares
Integral Health Asset Management, LLC Hedge Fund•Sector	−$2.4M −300.0K shares	Sold Off 0 shares
DIMENSIONAL FUND ADVISORS LP Long Only Manager	−$2.1M −157.4K shares	$20.4M 1.5M shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited RCUS in Q3 2025

New Positions: 14
New Value: $8.3M
Exited Positions: 25
Exited Value: $14.6M

New Positions

Institution	Position Value
S Standard Life Aberdeen plc Institution	$4.4M 331.7K shares
Vestal Point Capital, LP Hedge Fund•Long/Short	$3.4M 250.0K shares
Quantinno Capital Management LP Hedge Fund•Market Neutral	$206.9K 15.2K shares
ISAM Funds Ltd Hedge Fund•Quant	$189.8K 14.0K shares
A Abich Financial Wealth Management LLC RIA/Wealth	$69.3K 5.1K shares
SRS Capital Advisors, Inc. RIA/Wealth	$18.9K 1.4K shares
S Salomon & Ludwin, LLC Institution	$10.7K 798.0 shares
O Optiver Holding B.V. Institution	$9.1K 672.0 shares
Halbert, Hargrove/Russell LLC RIA/Wealth	$2.4K 180.0 shares
Sontag Advisory, LLC RIA/Wealth	$1.7K 126.0 shares

Exited Positions

Institution	Previous Position
Integral Health Asset Management, LLC Hedge Fund•Sector	$2.4M 300.0K shares
A AXA Institution	$1.9M 232.0K shares
C Cubist Systematic Strategies, LLC Institution	$1.8M 226.3K shares
S Squarepoint Ops LLC Hedge Fund•Quant	$1.6M 199.6K shares
Ikarian Capital, LLC Hedge Fund•Event Driven	$1.3M 163.4K shares
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$1.0M 126.3K shares
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	$948.0K 116.5K shares
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$809.6K 99.5K shares
Q Qube Research & Technologies Ltd Institution	$684.2K 84.0K shares
UBS OCONNOR LLC Long Only Manager	$431.2K 53.0K shares

Options Activity

Institutions with the largest Call and Put options positions in RCUS as of Q3 2025

Call Positions: 8
Call Value: $44.9M
Put Positions: 4
Put Value: $2.0M

Call Positions

Institution	Position Value
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$24.1M 17.7K contracts
BARCLAYS PLC Institution	$17.2M 12.7K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.4M 1.0K contracts
J JANE STREET GROUP, LLC Institution	$1.3M 939.0 contracts
CITIGROUP INC Institution	$405.3K 298.0 contracts
N NOMURA HOLDINGS INC Institution	$287.0K 211.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$247.5K 182.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	- - contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$814.6K 599.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$485.5K 357.0 contracts
CITIGROUP INC Institution	$405.3K 298.0 contracts
J JANE STREET GROUP, LLC Institution	$284.2K 209.0 contracts

Most Committed Institutions

Institutions with RCUS as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
GILEAD SCIENCES, INC. Institution	Daniel O'Day CEO	23.86% $427.4M	29.53% 31.4M shares	Q4 2024 Held for 11 months	$1.8B
SECTORAL ASSET MANAGEMENT INC Venture Capital	Jerome Georges Pfund CEO	3.14% $5.0M	0.35% 368.1K shares	Q1 2020 Held for 5y 8m	$159.6M
D DAFNA Capital Management LLC Hedge Fund•Event Driven	Nathan Fischel CEO	2.15% $8.5M	0.59% 627.6K shares	Q1 2020 Held for 5y 8m	$397.7M
S Siren, L.L.C. Institution	-	1.66% $39.6M	2.74% 2.9M shares	Q3 2024 Held for 1y 2m	$2.4B
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	1.52% $50.2M	3.47% 3.7M shares	Q3 2023 Held for 2y 2m	$3.3B
Decheng Capital LLC Venture Capital	Xiangmin Nmn Cui Managing Partner	1.30% $7.4M	0.51% 547.6K shares	Q4 2023 Held for 1y 11m	$573.2M
S Sofinnova Ventures Inc Venture Capital	James Irvin Healy Managing Partner	1.02% $16.6M	1.15% 1.2M shares	Q1 2025 Held for 8 months	$1.6B
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	Gregory Arthur Martinez CIO	0.98% $8.9M	0.61% 652.7K shares	Q2 2020 Held for 5y 5m	$910.1M
K Knott David M Jr Institution	-	0.54% $1.3M	0.09% 95.2K shares	Q1 2025 Held for 8 months	$238.7M
PDT Partners, LLC Hedge Fund•Quant	Peter (Nmn) Muller CEO	0.33% $5.3M	0.36% 388.3K shares	Q4 2023 Held for 1y 11m	$1.6B

Hedge Fund Spotlight

Discover hedge funds investing in RCUS

DAFNA Capital Management LLC

Hedge Fund • Event Driven

Portfolio ManagerNathan Fischel

Portfolio Value: $397.7M
Positions: 73
Last Reported: Q3 2025

Sector Allocation

Position in Arcus Biosciences

Market Value: $8.5M
Shares Held: 627.6K
Portfolio Weight: 2.15%
Owned Since: 2020-Q1

Top Holding	Sector	Market Value	Weight
1 Stereotaxis STXS	Medical - Instruments & Supplies Healthcare	$42.5M	10.70%
2 XBI SPDR S&P Biotech XBI	ETF ETF	$40.2M	10.12%
3 Revolution Medicines, Inc. RVMD	Biotechnology Healthcare	$30.7M	7.72%

View full profile

Arcus Biosciences

Overview

All Institutions

Hedge Funds

Ownership Breakdown

Biggest Investors

Net Capital Flow

Biggest Buyers

Biggest Sellers

Entry and Exit Activity

New Positions

Exited Positions

Options Activity

Call Positions

Put Positions

Most Committed Institutions

Hedge Fund Spotlight

Position in Arcus Biosciences

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