Rezolute

RZLT • NASDAQ

Rezolute is a biotechnology company in the healthcare sector on NASDAQ, led by Nevan Charles Elam, with a market cap of $166.9M. As of Q3 2025, 96% of shares are held by 116 institutional investors, with FEDERATED INVESTORS INC /PA/ as the largest holder at 15.45%.

Chief Executive OfficerNevan Charles Elam

Market Cap$166.9M

Biotechnology

Healthcare

Employees51.0

Websiterezolutebio.com

Country

United States of America

Overview

Overview of institutional ownership in RZLT as of Q3 2025 with a market cap of $853.6M

All Institutions

Institutions: 116
Value Held: $817.1M
Shares Held: 86.9M
Avg Position: $7.0M
Median Position: $525.9K

Hedge Funds

Hedge Funds: 24
Value Held: $151.6M
Shares Held: 16.1M
Avg Position: $6.3M
Median Position: $2.5M

Ownership Breakdown

Institutional (non-HF)

77.95%

$665.4M

Hedge Funds

17.76%

$151.6M

Retail & Other

4.28%

$36.6M

Based on market cap of $853.6M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in RZLT as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
FEDERATED INVESTORS INC /PA/ Long Only Manager	Gregory Philip Dulski Chairman	$131.9M 0.23% of portfolio	15.45% 14.0M shares	Q4 2020 Held for 4y 11m	$56.6B
FMR LLC Institution	-	$120.0M 0.01% of portfolio	14.06% 12.8M shares	Q1 2025 Held for 8 months	$1.92T
B BlackRock, Inc. Institution	-	$47.0M 0.00% of portfolio	5.51% 5.0M shares	Q2 2021 Held for 4y 5m	$5.67T
S Siren, L.L.C. Institution	-	$45.8M 1.92% of portfolio	5.36% 4.9M shares	Q3 2025 Held for 2 months	$2.4B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$41.5M 0.00% of portfolio	4.86% 4.4M shares	Q2 2021 Held for 4y 5m	$6.69T
Blackstone Group L.P. Institution	Jonathan D. Gray President	$28.4M 0.12% of portfolio	3.33% 3.0M shares	Q2 2022 Held for 3y 5m	$23.2B
MANGROVE PARTNERS Hedge Fund•Multi-Strategy	Nathaniel Hall August President	$27.1M 1.90% of portfolio	3.17% 2.9M shares	Q2 2025 Held for 5 months	$1.4B
Marshall Wace LLP Institution	Diana Lj Harrison President	$25.6M 0.03% of portfolio	3.00% 2.7M shares	Q2 2024 Held for 1y 5m	$90.3B
UBS Group AG Institution	Sergio P. Ermotti CEO	$25.3M 0.00% of portfolio	2.97% 2.7M shares	Q4 2023 Held for 1y 11m	$511.54B
G GREAT POINT PARTNERS LLC Private Equity	Jeffrey Robert Jay Managing Partner	$23.0M 10.16% of portfolio	2.70% 2.5M shares	Q4 2024 Held for 11 months	$226.8M

Net Capital Flow

Institutional buying and selling activity for RZLT in Q3 2025

Traded: +$109.5M
Buyers: 76
Sellers: 38
Total Bought: +$168.7M
Total Sold: −$59.2M
Avg Position: $6.5M

Biggest Buyers

Institution	Net Bought	Current Position
S Siren, L.L.C. Institution	+$45.8M +4.9M shares	$45.8M 4.9M shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$17.1M +1.8M shares	$17.1M 1.8M shares
STATE STREET CORP Institution	+$11.9M +1.3M shares	$19.7M 2.1M shares
BANK OF AMERICA CORP /DE/ Institution	+$11.4M +1.2M shares	$12.1M 1.3M shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$8.9M +945.9K shares	$10.9M 1.2M shares
B BlackRock, Inc. Institution	+$8.7M +922.9K shares	$47.0M 5.0M shares
2 22NW, LP Hedge Fund•Long/Short	+$7.7M +820.7K shares	$7.7M 820.7K shares
MANGROVE PARTNERS Hedge Fund•Multi-Strategy	+$5.5M +584.7K shares	$27.1M 2.9M shares
F FRED ALGER MANAGEMENT INC Long Only Manager	+$5.2M +557.4K shares	$5.2M 557.4K shares
GOLDMAN SACHS GROUP INC Institution	+$4.8M +508.4K shares	$5.1M 541.5K shares

Biggest Sellers

Institution	Net Sold	Current Position
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	−$10.2M −2.3M shares	Sold Off 0 shares
Woodline Partners LP Hedge Fund•Long/Short	−$9.1M −965.3K shares	$8.8M 938.8K shares
C Caligan Partners LP Hedge Fund•Activist	−$6.9M −1.5M shares	Sold Off 0 shares
G GREAT POINT PARTNERS LLC Private Equity	−$5.5M −581.7K shares	$23.0M 2.5M shares
Blackstone Group L.P. Institution	−$5.0M −536.4K shares	$28.4M 3.0M shares
S SPHERA FUNDS MANAGEMENT LTD. Institution	−$3.6M −387.5K shares	$3.4M 363.9K shares
UBS Group AG Institution	−$3.2M −341.2K shares	$25.3M 2.7M shares
UBS OCONNOR LLC Long Only Manager	−$2.0M −455.7K shares	Sold Off 0 shares
J J. Goldman & Co LP Hedge Fund•Multi-Strategy	−$1.8M −191.7K shares	$2.8M 294.3K shares
S Stonepine Capital Management, LLC Institution	−$1.7M −179.0K shares	$376.0K 40.0K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited RZLT in Q3 2025

New Positions: 29
New Value: $69.2M
Exited Positions: 10
Exited Value: $21.4M

New Positions

Institution	Position Value
S Siren, L.L.C. Institution	$45.8M 4.9M shares
2 22NW, LP Hedge Fund•Long/Short	$7.7M 820.7K shares
F FRED ALGER MANAGEMENT INC Long Only Manager	$5.2M 557.4K shares
K Knott David M Jr Institution	$2.6M 275.0K shares
WELLINGTON MANAGEMENT CO LLP Long Only Manager	$2.1M 227.5K shares
PANAGORA ASSET MANAGEMENT INC Hedge Fund•Quant	$1.6M 166.1K shares
C Campbell & CO Investment Adviser LLC Hedge Fund•Quant Macro	$1.1M 120.3K shares
NISA INVESTMENT ADVISORS L L C Long Only Manager	$554.6K 59.0K shares
R Rafferty Asset Management, LLC Institution	$497.1K 52.9K shares
ALTFEST L J & CO INC RIA/Wealth	$301.1K 32.0K shares

Exited Positions

Institution	Previous Position
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	$10.2M 2.3M shares
C Caligan Partners LP Hedge Fund•Activist	$6.9M 1.5M shares
UBS OCONNOR LLC Long Only Manager	$2.0M 455.7K shares
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$1.2M 266.7K shares
SUNRISE PARTNERS LIMITED PARTNERSHIP /CT Hedge Fund•Multi-Strategy	$557.5K 125.0K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	$235.6K 52.8K shares
Q Quadrature Capital Ltd Institution	$109.0K 24.5K shares
Retireful, LLC ETF Provider	$70.0K 15.7K shares
A AMERICAN CENTURY COMPANIES INC Institution	$57.4K 12.9K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	$46.2K 10.4K shares

Options Activity

Institutions with the largest Call and Put options positions in RZLT as of Q3 2025

Call Positions: 7
Call Value: $9.5M
Put Positions: 2
Put Value: $537.7K

Call Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$4.1M 4.4K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$2.6M 2.8K contracts
Hudson Bay Capital Management LP Hedge Fund•Multi-Strategy	$1.2M 1.3K contracts
Centiva Capital, LP Hedge Fund•Multi-Strategy	$753.9K 802.0 contracts
DLD Asset Management, LP Hedge Fund•Multi-Strategy	$469.8K 500.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$374.1K 398.0 contracts
J JANE STREET GROUP, LLC Institution	- - contracts

Put Positions

Institution	Position Value
J JANE STREET GROUP, LLC Institution	$296.1K 315.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$241.6K 257.0 contracts

Most Committed Institutions

Institutions with RZLT as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
C CAXTON CORP Institution	-	81.70% $18.7M	2.19% 2.0M shares	Q4 2020 Held for 4y 11m	$22.9M
G GREAT POINT PARTNERS LLC Private Equity	Jeffrey Robert Jay Managing Partner	10.16% $23.0M	2.70% 2.5M shares	Q4 2024 Held for 11 months	$226.8M
V Velan Capital Investment Management LP Institution	-	6.62% $7.1M	0.83% 750.0K shares	Q4 2021 Held for 3y 11m	$106.5M
R Rosalind Advisors, Inc. Institution	-	6.44% $17.0M	1.99% 1.8M shares	Q2 2025 Held for 5 months	$263.6M
2 22NW, LP Hedge Fund•Long/Short	James Paul Stoner CFO	4.03% $7.7M	0.90% 820.7K shares	Q3 2025 Held for 2 months	$191.5M
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	Jonathan Bo-Shing Chu Founder	2.01% $19.7M	2.31% 2.1M shares	Q1 2024 Held for 1y 8m	$983.0M
S Siren, L.L.C. Institution	-	1.92% $45.8M	5.36% 4.9M shares	Q3 2025 Held for 2 months	$2.4B
MANGROVE PARTNERS Hedge Fund•Multi-Strategy	Nathaniel Hall August President	1.90% $27.1M	3.17% 2.9M shares	Q2 2025 Held for 5 months	$1.4B
StemPoint Capital LP Hedge Fund•Long/Short	Sean Chua Tan President	1.74% $8.6M	1.01% 917.6K shares	Q2 2025 Held for 5 months	$495.9M
Vivo Capital, LLC Venture Capital	Jack Bech Nielsen Managing Partner	1.60% $19.9M	2.33% 2.1M shares	Q2 2022 Held for 3y 5m	$1.2B