ARS Pharmaceuticals, Inc.
SPRY • NASDAQ
ARS Pharmaceuticals, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Richard Lowenthal, M.S., MSEL, with a market cap of $1.0B. As of Q3 2025, 85% of shares are held by 188 institutional investors, with RA CAPITAL MANAGEMENT, LLC as the largest holder at 10.99%.
President and CEORichard Lowenthal, M.S., MSEL
Market Cap$1.0B
Biotechnology
Healthcare
Employees24.0
Websitears-pharma.com
Country
United States of America
Overview
Overview of institutional ownership in SPRY as of Q3 2025 with a market cap of $993.2M
All Institutions
- Institutions
- 188
- Value Held
- $840.4M
- Shares Held
- 83.6M
- Avg Position
- $4.5M
- Median Position
- $389.6K
Hedge Funds
- Hedge Funds
- 32
- Value Held
- $409.6M
- Shares Held
- 40.8M
- Avg Position
- $12.8M
- Median Position
- $1.5M
Ownership Breakdown
Based on market cap of $993.2M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in SPRY as of Q3 2025
| Institution | Position Value |
|---|---|
 RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | $109.2M 1.36% of portfolio |
 ORBIMED ADVISORS LLC Hedge Fund•Sector | $83.3M 2.02% of portfolio |
 DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short | $75.4M 1.25% of portfolio |
B BlackRock, Inc. Institution | $48.6M 0.00% of portfolio |
R Rubric Capital Management LP Hedge Fund•Long/Short | $45.2M 0.65% of portfolio |
 SR ONE CAPITAL MANAGEMENT, LP Venture Capital | $40.3M 5.83% of portfolio |
 VANGUARD GROUP INC Institution | $35.2M 0.00% of portfolio |
S Standard Life Aberdeen plc Institution | $31.1M 0.05% of portfolio |
 STATE STREET CORP Institution | $29.1M 0.00% of portfolio |
 ALLIANCEBERNSTEIN L.P. Long Only Manager | $26.6M 0.01% of portfolio |
Net Capital Flow
Institutional buying and selling activity for SPRY in Q3 2025
- Traded
- −$93.7M
- Buyers
- 112
- Sellers
- 86
- Total Bought
- +$177.5M
- Total Sold
- −$271.2M
- Avg Position
- $3.7M
Biggest Buyers
| Institution | Net Bought |
|---|---|
R Rubric Capital Management LP Hedge Fund•Long/Short | +$32.2M +3.2M shares |
 Casdin Capital, LLC Hedge Fund•Sector | +$16.1M +1.6M shares |
S Standard Life Aberdeen plc Institution | +$16.0M +1.6M shares |
 BAMCO INC /NY/ Long Only Manager | +$12.3M +1.2M shares |
Q Qube Research & Technologies Ltd Institution | +$10.4M +1.0M shares |
 Eversept Partners, LLC Hedge Fund•Long/Short | +$9.8M +976.5K shares |
STATE STREET CORP Institution | +$7.0M +700.8K shares |
 Trexquant Investment LP Hedge Fund•Quant | +$6.3M +631.7K shares |
 Janney Montgomery Scott LLC RIA/Wealth | +$6.2M +621.6K shares |
 FRANKLIN RESOURCES INC Institution | +$5.7M +569.3K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
A ADAGE CAPITAL PARTNERS GP LLC Institution | −$30.2M −1.7M shares |
 WELLINGTON MANAGEMENT CO LLP Long Only Manager | −$25.0M −1.4M shares |
 Octagon Capital Advisors LP Hedge Fund•Sector | −$23.6M −1.4M shares |
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short | −$22.3M −2.2M shares |
C Cormorant Asset Management, LLC Hedge Fund•Long/Short | −$19.2M −1.1M shares |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$15.3M −878.2K shares |
ALLIANCEBERNSTEIN L.P. Long Only Manager | −$11.9M −1.2M shares |
 NEXT CENTURY GROWTH INVESTORS LLC Long Only Manager | −$10.9M −622.8K shares |
 ARDSLEY ADVISORY PARTNERS Hedge Fund•Long/Short | −$8.3M −475.0K shares |
 FMR LLC Institution | −$8.3M −824.5K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited SPRY in Q3 2025
- New Positions
- 20
- New Value
- $28.2M
- Exited Positions
- 41
- Exited Value
- $198.9M
New Positions
| Institution | Position Value |
|---|---|
Casdin Capital, LLC Hedge Fund•Sector | $16.1M 1.6M shares |
 CenterBook Partners LP Hedge Fund•Market Neutral | $5.1M 512.4K shares |
E Empire Life Investments Inc. Institution | $3.6M 355.7K shares |
 OZ MANAGEMENT LP Hedge Fund•Multi-Strategy | $774.9K 77.1K shares |
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short | $595.3K 59.2K shares |
A AMERICAN ASSETS INC Institution | $552.8K 55.0K shares |
 Quantinno Capital Management LP Hedge Fund•Market Neutral | $406.7K 40.5K shares |
D DRW Securities, LLC Institution | $348.7K 35.7K shares |
 PRUDENTIAL FINANCIAL INC Institution | $277.4K 27.6K shares |
 Private Advisor Group, LLC RIA/Wealth | $206.9K 20.6K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
A ADAGE CAPITAL PARTNERS GP LLC Institution | $30.2M 1.7M shares |
WELLINGTON MANAGEMENT CO LLP Long Only Manager | $25.0M 1.4M shares |
Octagon Capital Advisors LP Hedge Fund•Sector | $23.6M 1.4M shares |
C Cormorant Asset Management, LLC Hedge Fund•Long/Short | $19.2M 1.1M shares |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $15.3M 878.2K shares |
NEXT CENTURY GROWTH INVESTORS LLC Long Only Manager | $10.9M 622.8K shares |
ARDSLEY ADVISORY PARTNERS Hedge Fund•Long/Short | $8.3M 475.0K shares |
 DRIEHAUS CAPITAL MANAGEMENT LLC Hedge Fund•Event Driven | $8.1M 464.0K shares |
P PEREGRINE CAPITAL MANAGEMENT LLC Long Only Manager | $8.0M 457.0K shares |
F First Turn Management, LLC Hedge Fund•Long/Short | $8.0M 456.0K shares |
Options Activity
Institutions with the largest Call and Put options positions in SPRY as of Q3 2025
- Call Positions
- 9
- Call Value
- $12.2M
- Put Positions
- 5
- Put Value
- $6.9M
Call Positions
| Institution | Position Value |
|---|---|
 Ikarian Capital, LLC Hedge Fund•Event Driven | $5.7M 5.6K contracts |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $2.9M 2.9K contracts |
 BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | $2.1M 2.0K contracts |
K K2 PRINCIPAL FUND, L.P. Institution | $635.2K 632.0 contracts |
 Caption Management, LLC Hedge Fund•Long/Short | $603.0K 600.0 contracts |
W WOLVERINE TRADING, LLC Institution | $218.7K 225.0 contracts |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $148.7K 148.0 contracts |
 DIADEMA PARTNERS LP Hedge Fund•Long/Short | - - contracts |
 LEVIN CAPITAL STRATEGIES, L.P. Hedge Fund•Multi-Strategy | - - contracts |
Put Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $2.6M 2.6K contracts |
 PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short | $2.0M 2.0K contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $1.3M 1.3K contracts |
OZ MANAGEMENT LP Hedge Fund•Multi-Strategy | $774.9K 771.0 contracts |
J JANE STREET GROUP, LLC Institution | $215.1K 214.0 contracts |
Most Committed Institutions
Institutions with SPRY as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
SR ONE CAPITAL MANAGEMENT, LP Venture Capital | 5.83% $40.3M |
K K2 PRINCIPAL FUND, L.P. Institution | 2.35% $6.2M |
 MPM Oncology Impact Management LP Institution | 2.14% $13.1M |
ORBIMED ADVISORS LLC Hedge Fund•Sector | 2.02% $83.3M |
Casdin Capital, LLC Hedge Fund•Sector | 1.39% $16.1M |
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | 1.36% $109.2M |
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short | 1.25% $75.4M |
N Nextech Invest, Ltd. Institution | 1.01% $6.6M |
Eversept Partners, LLC Hedge Fund•Long/Short | 0.75% $9.8M |
LEVIN CAPITAL STRATEGIES, L.P. Hedge Fund•Multi-Strategy | 0.70% $7.7M |
Hedge Fund Spotlight
Discover hedge funds investing in SPRY
Woodline Partners LP
Hedge Fund • Long/Short
Portfolio ManagerKarl Heinz Kroeker
- Portfolio Value
- $21.3B
- Positions
- 868
- Last Reported
- Q3 2025
Sector Allocation
Position in ARS Pharmaceuticals, Inc.
- Market Value
- $1.5M
- Shares Held
- 150.9K
- Portfolio Weight
- 0.01%
- Owned Since
- 2022-Q4
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Software - Infrastructure Technology | $615.5M | 2.90% | |
Semiconductors Technology | $603.3M | 2.84% | |
Consumer Electronics Technology | $522.1M | 2.46% |
