10x Genomics, Inc.

TXG • NASDAQ

10x Genomics, Inc. is a medical - healthcare information services company in the healthcare sector on NASDAQ, led by Kimberly J. Popovits, with a market cap of $2.0B. As of Q3 2025, 99% of shares are held by 308 institutional investors, with VANGUARD GROUP INC as the largest holder at 10.66%.

Chief Executive OfficerKimberly J. Popovits

Market Cap$2.0B

Medical - Healthcare Information Services

Healthcare

Employees1.3K

Website10xgenomics.com

Country

United States of America

Overview

Overview of institutional ownership in TXG as of Q3 2025 with a market cap of $1.5B

All Institutions

Institutions: 308
Value Held: $1.4B
Shares Held: 123.1M
Avg Position: $4.7M
Median Position: $401.6K

Hedge Funds

Hedge Funds: 42
Value Held: $275.7M
Shares Held: 23.6M
Avg Position: $6.6M
Median Position: $929.6K

Ownership Breakdown

Institutional (non-HF)

79.97%

$1.2B

Hedge Funds

18.95%

$275.7M

Retail & Other

1.09%

$15.8M

Based on market cap of $1.5B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in TXG as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
VANGUARD GROUP INC Institution	Salim Ramji CEO	$155.2M 0.00% of portfolio	10.66% 13.3M shares	Q3 2019 Held for 6y 2m	$6.69T
ARK Investment Management LLC ETF Provider	Catherine Duddy Wood CEO	$139.0M 0.84% of portfolio	9.55% 11.9M shares	Q2 2020 Held for 5y 5m	$16.5B
B BlackRock, Inc. Institution	-	$110.6M 0.00% of portfolio	7.60% 9.5M shares	Q3 2019 Held for 6y 2m	$5.67T
FMR LLC Institution	-	$98.9M 0.01% of portfolio	6.79% 8.5M shares	Q3 2019 Held for 6y 2m	$1.92T
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$63.6M 0.05% of portfolio	4.37% 5.4M shares	Q4 2021 Held for 3y 11m	$121.98B
S Sumitomo Mitsui Trust Holdings, Inc. Institution	-	$62.9M 0.04% of portfolio	4.32% 5.4M shares	Q2 2020 Held for 5y 5m	$173.79B
Nikko Asset Management Americas, Inc. Long Only Manager	James Mark Beyer Wesley CEO	$62.9M 0.61% of portfolio	4.32% 5.4M shares	Q2 2020 Held for 5y 5m	$10.3B
WELLINGTON MANAGEMENT CO LLP Long Only Manager	Jean Marie Hynes CEO	$50.1M 0.01% of portfolio	3.44% 4.3M shares	Q2 2025 Held for 5 months	$571.21B
Quantinno Capital Management LP Hedge Fund•Market Neutral	Hoon Nmn Kim CIO	$40.8M 0.11% of portfolio	2.81% 3.5M shares	Q2 2023 Held for 2y 5m	$36.6B
BANK OF AMERICA CORP /DE/ Institution	Brian T. Moynihan CEO	$39.9M 0.00% of portfolio	2.74% 3.4M shares	Q3 2019 Held for 6y 2m	$1.33T

Net Capital Flow

Institutional buying and selling activity for TXG in Q3 2025

Traded: +$42.4M
Buyers: 167
Sellers: 127
Total Bought: +$248.9M
Total Sold: −$206.5M
Avg Position: $4.1M

Biggest Buyers

Institution	Net Bought	Current Position
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$29.9M +2.6M shares	$63.6M 5.4M shares
WELLINGTON MANAGEMENT CO LLP Long Only Manager	+$28.0M +2.4M shares	$50.1M 4.3M shares
GOLDMAN SACHS GROUP INC Institution	+$24.2M +2.1M shares	$31.3M 2.7M shares
Quantinno Capital Management LP Hedge Fund•Market Neutral	+$14.7M +1.3M shares	$40.8M 3.5M shares
R ROYAL BANK OF CANADA Institution	+$14.3M +1.2M shares	$16.7M 1.4M shares
JPMORGAN CHASE & CO Institution	+$11.1M +951.5K shares	$12.6M 1.1M shares
HENDERSON GROUP PLC Institution	+$10.3M +883.2K shares	$10.9M 932.9K shares
VANGUARD GROUP INC Institution	+$9.8M +834.3K shares	$155.2M 13.3M shares
Lancaster Investment Management LLP Hedge Fund•Long/Short	+$7.3M +621.8K shares	$7.3M 621.8K shares
DIMENSIONAL FUND ADVISORS LP Long Only Manager	+$7.1M +610.1K shares	$8.8M 755.4K shares

Biggest Sellers

Institution	Net Sold	Current Position
ARK Investment Management LLC ETF Provider	−$23.4M −2.0M shares	$139.0M 11.9M shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$16.3M −1.4M shares	$31.5M 2.7M shares
Blue Water Life Science Advisors, LLC RIA/Wealth	−$12.7M −1.1M shares	Sold Off 0 shares
ALGERT COLDIRON INVESTORS LLC Hedge Fund•Quant	−$8.2M −705.4K shares	$6.7M 574.4K shares
MORGAN STANLEY RIA/Wealth	−$7.8M −669.7K shares	$32.9M 2.8M shares
S Sumitomo Mitsui Trust Holdings, Inc. Institution	−$7.4M −636.7K shares	$62.9M 5.4M shares
Nikko Asset Management Americas, Inc. Long Only Manager	−$7.4M −632.8K shares	$62.9M 5.4M shares
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy	−$7.2M −614.7K shares	$14.0M 1.2M shares
D D. E. Shaw & Co., Inc. Institution	−$6.8M −583.4K shares	$1.9M 162.9K shares
FMR LLC Institution	−$6.3M −538.4K shares	$98.9M 8.5M shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited TXG in Q3 2025

New Positions: 29
New Value: $20.9M
Exited Positions: 41
Exited Value: $48.3M

New Positions

Institution	Position Value
Lancaster Investment Management LLP Hedge Fund•Long/Short	$7.3M 621.8K shares
O OSSIAM Institution	$2.7M 229.3K shares
T Tao Capital Management LP Institution	$2.5M 210.9K shares
C CAPROCK Group, Inc. Fund of Funds	$1.7M 119.8K shares
U Universal- Beteiligungs- und Servicegesellschaft mbH Institution	$1.2M 100.9K shares
Friedenthal Financial RIA/Wealth	$923.9K 79.0K shares
Foundations Investment Advisors, LLC RIA/Wealth	$665.2K 56.9K shares
LEVEL FOUR ADVISORY SERVICES, LLC RIA/Wealth	$640.0K 54.8K shares
Kovitz Investment Group Partners, LLC RIA/Wealth	$498.3K 42.6K shares
Aaron Wealth Advisors LLC RIA/Wealth	$462.1K 39.5K shares

Exited Positions

Institution	Previous Position
Blue Water Life Science Advisors, LLC RIA/Wealth	$12.7M 1.1M shares
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$5.5M 475.3K shares
BANK OF NOVA SCOTIA / Institution	$3.8M 328.6K shares
I ING GROEP NV Institution	$3.3M 286.5K shares
I Invenomic Capital Management LP Hedge Fund•Long/Short	$2.7M 236.1K shares
A Amundi Institution	$2.7M 204.8K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$2.3M 195.9K shares
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy	$2.2M 189.6K shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	$1.4M 123.6K shares
WORLDQUANT MILLENNIUM QUANTITATIVE STRATEGIES LLC Hedge Fund•Multi-Strategy	$1.4M 117.0K shares

Options Activity

Institutions with the largest Call and Put options positions in TXG as of Q3 2025

Call Positions: 6
Call Value: $3.1M
Put Positions: 5
Put Value: $2.0M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$1.5M 1.3K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$769.2K 658.0 contracts
J JANE STREET GROUP, LLC Institution	$596.2K 510.0 contracts
P PEAK6 LLC Institution	$219.8K 188.0 contracts
HighTower Advisors, LLC RIA/Wealth	- - contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	- - contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$949.2K 812.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$514.4K 440.0 contracts
J JANE STREET GROUP, LLC Institution	$351.9K 301.0 contracts
Crawford Fund Management, LLC Hedge Fund•Long/Short	$187.0K 160.0 contracts
HighTower Advisors, LLC RIA/Wealth	$8.5K 200.0 contracts

Most Committed Institutions

Institutions with TXG as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Lancaster Investment Management LLP Hedge Fund•Long/Short	Christopher Richard Lamplough CEO	3.34% $7.3M	0.50% 621.8K shares	Q3 2025 Held for 2 months	$217.5M
T Tao Capital Management LP Institution	-	1.87% $2.5M	0.17% 210.9K shares	Q3 2025 Held for 2 months	$132.1M
Exome Asset Management LLC Hedge Fund•Sector	Alex R Forschner President	1.29% $1.9M	0.13% 163.7K shares	Q2 2025 Held for 5 months	$148.0M
Sands Capital Ventures, LLC Venture Capital	Ian W Ratcliffe Managing Partner	1.23% $5.6M	0.39% 481.8K shares	Q2 2022 Held for 3y 5m	$456.4M
ARK Investment Management LLC ETF Provider	Catherine Duddy Wood CEO	0.84% $139.0M	9.55% 11.9M shares	Q2 2020 Held for 5y 5m	$16.5B
Nikko Asset Management Americas, Inc. Long Only Manager	James Mark Beyer Wesley CEO	0.61% $62.9M	4.32% 5.4M shares	Q2 2020 Held for 5y 5m	$10.3B
Friedenthal Financial RIA/Wealth	Mark Friedenthal President	0.48% $923.9K	0.06% 79.0K shares	Q3 2025 Held for 2 months	$193.7M
Bayforest Capital Ltd Hedge Fund•Quant	Theodoros Tsagaris CEO	0.40% $839.7K	0.06% 71.8K shares	Q4 2024 Held for 11 months	$209.9M
D Davy Asset Management Ltd Institution	-	0.38% $5.6M	0.39% 479.3K shares	Q2 2024 Held for 1y 5m	$1.5B
FINANCIAL CONSULATE, INC RIA/Wealth	Michael Patrick Mccarthy CEO	0.26% $1.8M	0.13% 156.5K shares	Q3 2025 Held for 2 months	$701.1M