Ventyx Biosciences

VTYX • NASDAQ

Ventyx Biosciences is a biotechnology company in the healthcare sector on NASDAQ, led by Raju Mohan, Ph.D., with a market cap of $584.4M. As of Q3 2025, 61% of shares are held by 108 institutional investors, with Affinity Asset Advisors, LLC as the largest holder at 5.5%.

PresidentRaju Mohan, Ph.D.

Market Cap$584.4M

Biotechnology

Healthcare

Employees74.0

Websiteventyxbio.com

Country

United States of America

Overview

Overview of institutional ownership in VTYX as of Q3 2025 with a market cap of $221.8M

All Institutions

Institutions: 108
Value Held: $136.4M
Shares Held: 43.8M
Avg Position: $1.3M
Median Position: $252.2K

Hedge Funds

Hedge Funds: 28
Value Held: $63.9M
Shares Held: 20.5M
Avg Position: $2.3M
Median Position: $698.5K

Ownership Breakdown

Institutional (non-HF)

32.68%

$72.5M

Hedge Funds

28.82%

$63.9M

Retail & Other

38.51%

$85.4M

Based on market cap of $221.8M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in VTYX as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	Jonathan Bo-Shing Chu Founder	$12.2M 1.24% of portfolio	5.50% 3.9M shares	Q2 2025 Held for 5 months	$983.0M
VANGUARD GROUP INC Institution	Salim Ramji CEO	$11.7M 0.00% of portfolio	5.29% 3.8M shares	Q4 2021 Held for 3y 11m	$6.69T
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	Steven Alan Cohen CEO	$10.0M 0.02% of portfolio	4.50% 3.2M shares	Q4 2024 Held for 11 months	$43.2B
T TANG CAPITAL MANAGEMENT LLC Institution	-	$9.6M 0.38% of portfolio	4.35% 3.1M shares	Q4 2023 Held for 1y 11m	$2.5B
Marshall Wace LLP Institution	Diana Lj Harrison President	$7.2M 0.01% of portfolio	3.25% 2.3M shares	Q2 2025 Held for 5 months	$90.3B
Vestal Point Capital, LP Hedge Fund•Long/Short	Ryan Christopher Wilder CIO	$6.4M 0.32% of portfolio	2.87% 2.1M shares	Q2 2024 Held for 1y 5m	$2.0B
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	Kenneth Cordele Griffin CEO	$5.8M 0.00% of portfolio	2.64% 1.9M shares	Q4 2021 Held for 3y 11m	$122.08B
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$5.1M 0.00% of portfolio	2.32% 1.7M shares	Q4 2021 Held for 3y 11m	$121.98B
Ikarian Capital, LLC Hedge Fund•Event Driven	Neil Tristan Shahrestani CEO	$4.1M 0.82% of portfolio	1.84% 1.3M shares	Q1 2023 Held for 2y 8m	$494.3M
B BlackRock, Inc. Institution	-	$3.7M 0.00% of portfolio	1.66% 1.2M shares	Q4 2021 Held for 3y 11m	$5.67T

Net Capital Flow

Institutional buying and selling activity for VTYX in Q3 2025

Traded: +$23.4K
Buyers: 55
Sellers: 55
Total Bought: +$24.4M
Total Sold: −$24.4M
Avg Position: $1.0M

Biggest Buyers

Institution	Net Bought	Current Position
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	+$3.2M +1.0M shares	$3.2M 1.0M shares
6 683 Capital Management, LLC Hedge Fund•Long/Short	+$3.1M +1.0M shares	$3.1M 1.0M shares
VANGUARD GROUP INC Institution	+$1.9M +607.7K shares	$11.7M 3.8M shares
D D. E. Shaw & Co., Inc. Institution	+$1.5M +473.8K shares	$1.6M 522.7K shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$1.4M +436.1K shares	$1.4M 436.1K shares
Ikarian Capital, LLC Hedge Fund•Event Driven	+$1.1M +342.0K shares	$4.1M 1.3M shares
JPMORGAN CHASE & CO Institution	+$902.4K +290.2K shares	$2.3M 748.1K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$765.2K +246.0K shares	$5.1M 1.7M shares
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	+$753.3K +242.2K shares	$753.3K 242.2K shares
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy	+$666.1K +214.2K shares	$666.1K 214.2K shares

Biggest Sellers

Institution	Net Sold	Current Position
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$8.4M −2.7M shares	$10.0M 3.2M shares
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	−$1.9M −611.8K shares	$12.2M 3.9M shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$1.7M −546.4K shares	$570.5K 183.4K shares
Monaco Asset Management SAM RIA/Wealth	−$1.7M −536.3K shares	$701.6K 225.6K shares
Sio Capital Management, LLC Hedge Fund•Long/Short	−$1.5M −478.8K shares	$2.6M 829.2K shares
BANK OF AMERICA CORP /DE/ Institution	−$961.4K −309.1K shares	$1.6M 529.2K shares
Q Qiming U.S. Ventures Management, LLC Institution	−$882.2K −412.2K shares	Sold Off 0 shares
MORGAN STANLEY RIA/Wealth	−$862.3K −277.3K shares	$758.1K 243.8K shares
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	−$735.9K −236.6K shares	$576.8K 185.5K shares
B BlackRock, Inc. Institution	−$574.6K −184.8K shares	$3.7M 1.2M shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited VTYX in Q3 2025

New Positions: 9
New Value: $4.8M
Exited Positions: 23
Exited Value: $2.8M

New Positions

Institution	Position Value
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	$3.2M 1.0M shares
StemPoint Capital LP Hedge Fund•Long/Short	$520.8K 167.5K shares
CITIZENS FINANCIAL GROUP INC/RI Institution	$442.2K 142.2K shares
M Man Group plc Institution	$250.6K 80.6K shares
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$221.4K 71.2K shares
A Arrowpoint Investment Partners Pte. Ltd. Institution	$83.5K 26.9K shares
P Persistent Asset Partners Ltd Institution	$50.7K 16.3K shares
SRS Capital Advisors, Inc. RIA/Wealth	$22.4K 7.2K shares
Sontag Advisory, LLC RIA/Wealth	$2.6K 844.0 shares

Exited Positions

Institution	Previous Position
Q Qiming U.S. Ventures Management, LLC Institution	$882.2K 412.2K shares
B Brevan Howard Capital Management LP Institution	$245.7K 114.8K shares
H HRT FINANCIAL LLC Institution	$195.7K 91.4K shares
Jain Global LLC Hedge Fund•Multi-Strategy	$180.2K 84.2K shares
UBS OCONNOR LLC Long Only Manager	$169.1K 79.0K shares
Aster Capital Management Ltd RIA/Wealth	$165.5K 77.3K shares
Y Y-Intercept Ltd Institution	$148.2K 69.2K shares
S Shay Capital LLC Institution	$121.2K 56.6K shares
BAILARD, INC. RIA/Wealth	$88.4K 41.3K shares
HPM Partners LLC RIA/Wealth	$82.1K 38.4K shares

Options Activity

Institutions with the largest Call and Put options positions in VTYX as of Q3 2025

Call Positions: 3
Call Value: $471.5K
Put Positions: 2
Put Value: $136.2K

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$265.9K 855.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$136.2K 438.0 contracts
J JANE STREET GROUP, LLC Institution	$69.4K 223.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$83.0K 267.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$53.2K 171.0 contracts

Most Committed Institutions

Institutions with VTYX as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
SECTORAL ASSET MANAGEMENT INC Venture Capital	Jerome Georges Pfund CEO	2.16% $3.4M	1.55% 1.1M shares	Q2 2025 Held for 5 months	$159.6M
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	Jonathan Bo-Shing Chu Founder	1.24% $12.2M	5.50% 3.9M shares	Q2 2025 Held for 5 months	$983.0M
Ikarian Capital, LLC Hedge Fund•Event Driven	Neil Tristan Shahrestani CEO	0.82% $4.1M	1.84% 1.3M shares	Q1 2023 Held for 2y 8m	$494.3M
Sio Capital Management, LLC Hedge Fund•Long/Short	Judah Zvi Drillick CEO	0.65% $2.6M	1.16% 829.2K shares	Q1 2024 Held for 1y 8m	$395.2M
T TANG CAPITAL MANAGEMENT LLC Institution	-	0.38% $9.6M	4.35% 3.1M shares	Q4 2023 Held for 1y 11m	$2.5B
S SPHERA FUNDS MANAGEMENT LTD. Institution	-	0.33% $1.4M	0.62% 440.1K shares	Q4 2023 Held for 1y 11m	$416.3M
R Redmile Group, LLC Hedge Fund•Sector	Amrit Nmn Nagpal Managing Partner	0.32% $3.3M	1.51% 1.1M shares	Q3 2022 Held for 3y 2m	$1.0B
Vestal Point Capital, LP Hedge Fund•Long/Short	Ryan Christopher Wilder CIO	0.32% $6.4M	2.87% 2.1M shares	Q2 2024 Held for 1y 5m	$2.0B
6 683 Capital Management, LLC Hedge Fund•Long/Short	Ari Jonathan Zweiman Managing Partner	0.29% $3.1M	1.40% 1.0M shares	Q3 2025 Held for 2 months	$1.1B
Monaco Asset Management SAM RIA/Wealth	Kirstin Lynn Hark Director	0.27% $701.6K	0.32% 225.6K shares	Q4 2024 Held for 11 months	$256.5M

Hedge Fund Spotlight

Discover hedge funds investing in VTYX

SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC

Hedge Fund • Distressed

Portfolio ManagerLaurence L. Gottlieb

Portfolio Value: $2.6B
Positions: 549
Last Reported: Q3 2025

Sector Allocation

Position in Ventyx Biosciences

Market Value: $64.6K
Shares Held: 20.8K
Portfolio Weight: 0.00%
Owned Since: 2024-Q4

Top Holding	Sector	Market Value	Weight
1 Newmont NEM	Gold Basic Materials	$78.8M	3.08%
2 General Dynamics GD	Aerospace & Defense Industrials	$58.3M	2.28%
3 Honeywell International HON	Conglomerates Industrials	$51.1M	2.00%