Acrivon Therapeutics, Inc.

ACRV • NASDAQ

Acrivon Therapeutics, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Peter Blume-Jensen, with a market cap of $79.8M. As of Q3 2025, 56% of shares are held by 45 institutional investors, with RA CAPITAL MANAGEMENT, LLC as the largest holder at 26.52%.

CEOPeter Blume-Jensen

Market Cap$79.8M

Biotechnology

Healthcare

Employees61.0

Websiteacrivon.com

Country

United States of America

Overview

Overview of institutional ownership in ACRV as of Q3 2025 with a market cap of $56.9M

All Institutions

Institutions: 45
Value Held: $31.6M
Shares Held: 17.5M
Avg Position: $702.3K
Median Position: $41.4K

Hedge Funds

Hedge Funds: 9
Value Held: $20.5M
Shares Held: 11.3M
Avg Position: $2.3M
Median Position: $335.3K

Ownership Breakdown

Institutional (non-HF)

19.53%

$11.1M

Hedge Funds

35.98%

$20.5M

Retail & Other

44.49%

$25.3M

Based on market cap of $56.9M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in ACRV as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	$15.1M 0.19% of portfolio	26.52% 8.3M shares	Q4 2022 Held for 2y 11m	$8.1B
Sands Capital Ventures, LLC Venture Capital	Ian W Ratcliffe Managing Partner	$3.8M 0.84% of portfolio	6.75% 2.1M shares	Q4 2022 Held for 2y 11m	$456.4M
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	Kenneth Cordele Griffin CEO	$2.8M 0.00% of portfolio	4.90% 1.5M shares	Q4 2022 Held for 2y 11m	$122.08B
WELLINGTON MANAGEMENT CO LLP Long Only Manager	Jean Marie Hynes CEO	$1.6M 0.00% of portfolio	2.82% 888.1K shares	Q4 2022 Held for 2y 11m	$571.21B
UBS Group AG Institution	Sergio P. Ermotti CEO	$1.2M 0.00% of portfolio	2.17% 683.2K shares	Q4 2022 Held for 2y 11m	$511.54B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$1.1M 0.00% of portfolio	1.99% 626.1K shares	Q1 2023 Held for 2y 8m	$6.69T
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	$1.1M 0.00% of portfolio	1.98% 623.4K shares	Q1 2024 Held for 1y 8m	$75.8B
A ACORN CAPITAL ADVISORS, LLC Venture Capital	Anthony Michael Gallo CCO	$733.5K 0.37% of portfolio	1.29% 405.2K shares	Q4 2024 Held for 11 months	$197.0M
B BlackRock, Inc. Institution	-	$599.0K 0.00% of portfolio	1.05% 331.0K shares	Q1 2023 Held for 2y 8m	$5.67T
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	Scott David Hoffman CEO	$577.8K 0.00% of portfolio	1.01% 319.2K shares	Q2 2025 Held for 5 months	$62.0B

Net Capital Flow

Institutional buying and selling activity for ACRV in Q3 2025

Traded: −$169.8K
Buyers: 15
Sellers: 29
Total Bought: +$2.3M
Total Sold: −$2.4M
Avg Position: $554.5K

Biggest Buyers

Institution	Net Bought	Current Position
UBS Group AG Institution	+$1.2M +682.8K shares	$1.2M 683.2K shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$249.8K +138.0K shares	$577.8K 319.2K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	+$206.5K +114.1K shares	$1.1M 623.4K shares
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy	+$188.1K +103.9K shares	$247.1K 136.5K shares
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	+$166.5K +92.0K shares	$166.5K 92.0K shares
ALGERT COLDIRON INVESTORS LLC Hedge Fund•Quant	+$80.8K +44.6K shares	$80.8K 44.6K shares
VANGUARD GROUP INC Institution	+$59.6K +32.9K shares	$1.1M 626.1K shares
GEODE CAPITAL MANAGEMENT LLC ETF Provider	+$50.1K +27.7K shares	$347.7K 192.0K shares
A AAFCPAs Wealth Management, LLC RIA/Wealth	+$19.3K +10.7K shares	$19.3K 10.7K shares
R ROYAL BANK OF CANADA Institution	+$1.7K +917.0 shares	$1.7K 948.0 shares

Biggest Sellers

Institution	Net Sold	Current Position
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$641.1K −354.2K shares	$2.8M 1.5M shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	−$454.9K −382.2K shares	Sold Off 0 shares
GOLDMAN SACHS GROUP INC Institution	−$217.8K −120.3K shares	$35.7K 19.7K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$200.9K −111.0K shares	$335.3K 185.2K shares
H HRT FINANCIAL LLC Institution	−$173.6K −145.9K shares	Sold Off 0 shares
B BlackRock, Inc. Institution	−$138.8K −76.7K shares	$599.0K 331.0K shares
X XTX Topco Ltd Institution	−$127.0K −70.2K shares	$65.1K 36.0K shares
S Squarepoint Ops LLC Hedge Fund•Quant	−$87.4K −48.3K shares	$188.8K 104.3K shares
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	−$75.7K −63.6K shares	Sold Off 0 shares
Marshall Wace LLP Institution	−$57.0K −31.5K shares	$271.0K 149.7K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited ACRV in Q3 2025

New Positions: 3
New Value: $248.0K
Exited Positions: 11
Exited Value: $857.3K

New Positions

Institution	Position Value
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	$166.5K 92.0K shares
ALGERT COLDIRON INVESTORS LLC Hedge Fund•Quant	$80.8K 44.6K shares
E EverSource Wealth Advisors, LLC RIA/Wealth	$675.0 373.0 shares

Exited Positions

Institution	Previous Position
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	$454.9K 382.2K shares
H HRT FINANCIAL LLC Institution	$173.6K 145.9K shares
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	$75.7K 63.6K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$52.2K 43.9K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	$26.5K 22.3K shares
Q Quadrature Capital Ltd Institution	$26.3K 22.2K shares
S SG Americas Securities, LLC Institution	$18.2K 15.3K shares
Q Qube Research & Technologies Ltd Institution	$15.1K 12.7K shares
G Ground Swell Capital, LLC Hedge Fund•Multi-Strategy	$14.5K 12.2K shares
True Wealth Design, LLC RIA/Wealth	$210.0 176.0 shares

Options Activity

Institutions with the largest Call and Put options positions in ACRV as of Q3 2025

Call Positions: 0
Call Value: -
Put Positions: 0
Put Value: -

Call Positions

Institution	Position Value
No call positions found

Put Positions

Institution	Position Value
No put positions found

Most Committed Institutions

Institutions with ACRV as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Sands Capital Ventures, LLC Venture Capital	Ian W Ratcliffe Managing Partner	0.84% $3.8M	6.75% 2.1M shares	Q4 2022 Held for 2y 11m	$456.4M
A ACORN CAPITAL ADVISORS, LLC Venture Capital	Anthony Michael Gallo CCO	0.37% $733.5K	1.29% 405.2K shares	Q4 2024 Held for 11 months	$197.0M
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	0.19% $15.1M	26.52% 8.3M shares	Q4 2022 Held for 2y 11m	$8.1B
A AAFCPAs Wealth Management, LLC RIA/Wealth	Andrew Edmund Hammond CCO	0.01% $19.3K	0.03% 10.7K shares	Q2 2023 Held for 2y 5m	$220.1M
X XTX Topco Ltd Institution	-	0.00% $65.1K	0.11% 36.0K shares	Q2 2025 Held for 5 months	$1.9B
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	Kenneth Cordele Griffin CEO	0.00% $2.8M	4.90% 1.5M shares	Q4 2022 Held for 2y 11m	$122.08B
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	0.00% $1.1M	1.98% 623.4K shares	Q1 2024 Held for 1y 8m	$75.8B
ALGERT COLDIRON INVESTORS LLC Hedge Fund•Quant	Ryan Zentner Lafond CIO	0.00% $80.8K	0.14% 44.6K shares	Q3 2025 Held for 2 months	$6.0B
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	Scott David Hoffman CEO	0.00% $577.8K	1.01% 319.2K shares	Q2 2025 Held for 5 months	$62.0B
B BRIDGEWAY CAPITAL MANAGEMENT INC Long Only Manager	John Noland Ryan Montgomery CEO	0.00% $41.4K	0.07% 22.9K shares	Q4 2023 Held for 1y 11m	$4.7B

Hedge Fund Spotlight

Discover hedge funds investing in ACRV

BAKER BROS. ADVISORS LP

Hedge Fund • Sector

Portfolio ManagerScott Lawrence Lessing

Portfolio Value: $10.8B
Positions: 88
Last Reported: Q3 2025

Sector Allocation

Position in Acrivon Therapeutics, Inc.

Market Value: $41.3K
Shares Held: 22.8K
Portfolio Weight: 0.00%
Owned Since: 2024-Q1

Top Holding	Sector	Market Value	Weight
1 Incyte INCY	Biotechnology Healthcare	$2.6B	24.14%
2 Madrigal Pharmaceuticals, Inc. MDGL	Biotechnology Healthcare	$982.3M	9.10%
3 Insmed INSM	Biotechnology Healthcare	$965.4M	8.94%