Astria Therapeutics, Inc.

ATXS • NASDAQ

Astria Therapeutics, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Jill C. Milne, with a market cap of $738.1M. As of Q3 2025, 99% of shares are held by 114 institutional investors, with PERCEPTIVE ADVISORS LLC as the largest holder at 11.49%.

President, Chief Executive Officer, and principal financial officerJill C. Milne

Market Cap$738.1M

Biotechnology

Healthcare

Employees59.0

Websiteastriatx.com

Country

United States of America

Overview

Overview of institutional ownership in ATXS as of Q3 2025 with a market cap of $410.8M

All Institutions

Institutions: 114
Value Held: $407.8M
Shares Held: 56.0M
Avg Position: $3.6M
Median Position: $192.2K

Hedge Funds

Hedge Funds: 26
Value Held: $177.2M
Shares Held: 24.3M
Avg Position: $6.8M
Median Position: $1.3M

Ownership Breakdown

Institutional (non-HF)

56.12%

$230.6M

Hedge Funds

43.13%

$177.2M

Retail & Other

0.75%

$3.1M

Based on market cap of $410.8M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in ATXS as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short	Joseph Eric Edelman CEO	$47.2M 1.37% of portfolio	11.49% 6.5M shares	Q1 2021 Held for 4y 8m	$3.5B
FMR LLC Institution	-	$37.5M 0.00% of portfolio	9.13% 5.2M shares	Q1 2022 Held for 3y 8m	$1.92T
Vestal Point Capital, LP Hedge Fund•Long/Short	Ryan Christopher Wilder CIO	$36.1M 1.83% of portfolio	8.78% 5.0M shares	Q1 2024 Held for 1y 8m	$2.0B
FCPM III SERVICES B.V. Real Assets	Andrew David Lindner Managing Partner	$29.9M 5.98% of portfolio	7.28% 4.1M shares	Q4 2024 Held for 11 months	$500.4M
Fairmount Funds Management LLC Hedge Fund•Sector	Peter Evan Harwin Managing Partner	$25.9M 2.33% of portfolio	6.30% 3.6M shares	Q1 2021 Held for 4y 8m	$1.1B
B BlackRock, Inc. Institution	-	$25.4M 0.00% of portfolio	6.18% 3.5M shares	Q1 2017 Held for 8y 8m	$5.67T
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$22.1M 0.02% of portfolio	5.38% 3.0M shares	Q2 2020 Held for 5y 5m	$121.98B
TCG Crossover Management, LLC Venture Capital	Chen Ming Yu Managing Partner	$20.1M 1.00% of portfolio	4.89% 2.8M shares	Q1 2024 Held for 1y 8m	$2.0B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$19.2M 0.00% of portfolio	4.68% 2.6M shares	Q2 2015 Held for 10y 5m	$6.69T
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	$17.9M 1.01% of portfolio	4.35% 2.5M shares	Q4 2023 Held for 1y 11m	$1.8B

Net Capital Flow

Institutional buying and selling activity for ATXS in Q3 2025

Traded: −$9.3M
Buyers: 52
Sellers: 49
Total Bought: +$12.8M
Total Sold: −$22.1M
Avg Position: $3.3M

Biggest Buyers

Institution	Net Bought	Current Position
Vestal Point Capital, LP Hedge Fund•Long/Short	+$3.2M +434.0K shares	$36.1M 5.0M shares
MORGAN STANLEY RIA/Wealth	+$2.5M +338.9K shares	$6.3M 864.4K shares
J JANE STREET GROUP, LLC Institution	+$1.1M +145.1K shares	$1.6M 219.3K shares
VANGUARD GROUP INC Institution	+$855.5K +117.5K shares	$19.2M 2.6M shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	+$767.9K +105.5K shares	$2.9M 395.3K shares
PANAGORA ASSET MANAGEMENT INC Hedge Fund•Quant	+$514.6K +70.7K shares	$1.2M 169.1K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$471.7K +64.8K shares	$22.1M 3.0M shares
GOLDMAN SACHS GROUP INC Institution	+$377.5K +51.9K shares	$1.7M 229.2K shares
Quest Partners LLC Hedge Fund•Quant Macro	+$366.9K +50.4K shares	$470.3K 64.6K shares
C Cubist Systematic Strategies, LLC Institution	+$254.1K +34.9K shares	$524.7K 72.1K shares

Biggest Sellers

Institution	Net Sold	Current Position
FMR LLC Institution	−$9.5M −1.3M shares	$37.5M 5.2M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$2.4M −326.1K shares	$6.2M 849.0K shares
Sio Capital Management, LLC Hedge Fund•Long/Short	−$1.7M −318.3K shares	Sold Off 0 shares
B BlackRock, Inc. Institution	−$1.5M −210.6K shares	$25.4M 3.5M shares
Logos Global Management LP Hedge Fund•Long/Short	−$1.5M −200.0K shares	$3.6M 500.0K shares
UBS Group AG Institution	−$961.7K −132.1K shares	$4.2M 580.2K shares
J Jump Financial, LLC Institution	−$424.5K −79.2K shares	Sold Off 0 shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	−$405.6K −55.7K shares	$1.4M 193.9K shares
WELLINGTON MANAGEMENT CO LLP Long Only Manager	−$351.7K −48.3K shares	$1.1M 145.4K shares
STATE STREET CORP Institution	−$316.3K −43.5K shares	$6.5M 890.7K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited ATXS in Q3 2025

New Positions: 5
New Value: $274.6K
Exited Positions: 10
Exited Value: $3.3M

New Positions

Institution	Position Value
Atom Investors LP Hedge Fund•Market Neutral	$174.2K 23.9K shares
B Brevan Howard Capital Management LP Institution	$97.6K 13.4K shares
PRINCIPAL SECURITIES, INC. RIA/Wealth	$2.2K 300.0 shares
O Optiver Holding B.V. Institution	$641.0 88.0 shares
Steward Partners Investment Advisory, LLC RIA/Wealth	$22.0 3.0 shares

Exited Positions

Institution	Previous Position
Sio Capital Management, LLC Hedge Fund•Long/Short	$1.7M 318.3K shares
J Jump Financial, LLC Institution	$424.5K 79.2K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$299.0K 55.8K shares
C CANTOR FITZGERALD, L. P. Institution	$292.8K 54.6K shares
X XTX Topco Ltd Institution	$194.3K 36.2K shares
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	$165.8K 30.9K shares
H HRT FINANCIAL LLC Institution	$119.9K 22.4K shares
P ProShare Advisors LLC Institution	$58.3K 10.9K shares
Hartland & Co., LLC RIA/Wealth	$2.2K 416.0 shares
Caitong International Asset Management Co., Ltd RIA/Wealth	$123.0 23.0 shares

Options Activity

Institutions with the largest Call and Put options positions in ATXS as of Q3 2025

Call Positions: 3
Call Value: $319.6K
Put Positions: 3
Put Value: $406.2K

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$227.9K 313.0 contracts
Walleye Trading LLC RIA/Wealth	$58.2K 80.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$33.5K 46.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$369.8K 508.0 contracts
Walleye Trading LLC RIA/Wealth	$19.7K 27.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$16.7K 23.0 contracts

Most Committed Institutions

Institutions with ATXS as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
FCPM III SERVICES B.V. Real Assets	Andrew David Lindner Managing Partner	5.98% $29.9M	7.28% 4.1M shares	Q4 2024 Held for 11 months	$500.4M
Fairmount Funds Management LLC Hedge Fund•Sector	Peter Evan Harwin Managing Partner	2.33% $25.9M	6.30% 3.6M shares	Q1 2021 Held for 4y 8m	$1.1B
Vestal Point Capital, LP Hedge Fund•Long/Short	Ryan Christopher Wilder CIO	1.83% $36.1M	8.78% 5.0M shares	Q1 2024 Held for 1y 8m	$2.0B
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short	Joseph Eric Edelman CEO	1.37% $47.2M	11.49% 6.5M shares	Q1 2021 Held for 4y 8m	$3.5B
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	1.01% $17.9M	4.35% 2.5M shares	Q4 2023 Held for 1y 11m	$1.8B
TCG Crossover Management, LLC Venture Capital	Chen Ming Yu Managing Partner	1.00% $20.1M	4.89% 2.8M shares	Q1 2024 Held for 1y 8m	$2.0B
Vivo Capital, LLC Venture Capital	Jack Bech Nielsen Managing Partner	0.91% $11.3M	2.75% 1.6M shares	Q3 2022 Held for 3y 2m	$1.2B
D DAFNA Capital Management LLC Hedge Fund•Event Driven	Nathan Fischel CEO	0.59% $2.3M	0.57% 319.8K shares	Q1 2023 Held for 2y 8m	$397.7M
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	Daniel J. Mack Managing Partner	0.48% $7.8M	1.90% 1.1M shares	Q2 2024 Held for 1y 5m	$1.6B
S SPHERA FUNDS MANAGEMENT LTD. Institution	-	0.44% $1.8M	0.45% 251.2K shares	Q4 2022 Held for 2y 11m	$416.3M

Hedge Fund Spotlight

Discover hedge funds investing in ATXS

AXQ CAPITAL, LP

Hedge Fund • Market Neutral

Portfolio ManagerTaro Hsu Kuriyama

Portfolio Value: $261.9M
Positions: 552
Last Reported: Q3 2025

Sector Allocation

Position in Astria Therapeutics, Inc.

Market Value: $115.2K
Shares Held: 15.8K
Portfolio Weight: 0.04%
Owned Since: 2025-Q1

Top Holding	Sector	Market Value	Weight
1 Dover DOV	Industrial - Machinery Industrials	$2.0M	0.75%
2 Arista Networks ANET	Computer Hardware Technology	$1.9M	0.72%
3 Vistra VST	Independent Power Producers Utilities	$1.9M	0.71%