Neurogene
NGNE • NASDAQ
Neurogene is a biotechnology company in the healthcare sector on NASDAQ, led by Rachel McMinn, with a market cap of $324.0M. As of Q3 2025, 107% of shares are held by 88 institutional investors, with Samsara BioCapital, LLC as the largest holder at 12.03%.
CEO of Neurogene, Inc.Rachel McMinn
Market Cap$324.0M
Biotechnology
Healthcare
Employees91.0
Websiteneurogene.com
Country
United States of America
Overview
Overview of institutional ownership in NGNE as of Q3 2025 with a market cap of $247.3M
All Institutions
- Institutions
- 88
- Value Held
- $265.2M
- Shares Held
- 15.3M
- Avg Position
- $3.0M
- Median Position
- $229.7K
Hedge Funds
- Hedge Funds
- 19
- Value Held
- $145.8M
- Shares Held
- 8.4M
- Avg Position
- $7.7M
- Median Position
- $1.8M
Ownership Breakdown
Based on market cap of $247.3M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in NGNE as of Q3 2025
| Institution | Position Value |
|---|---|
 Samsara BioCapital, LLC Venture Capital | $29.8M 3.89% of portfolio |
 RTW INVESTMENTS, LLC Hedge Fund•Sector | $23.6M 0.29% of portfolio |
R Redmile Group, LLC Hedge Fund•Sector | $22.5M 2.19% of portfolio |
 Casdin Capital, LLC Hedge Fund•Sector | $22.4M 1.94% of portfolio |
 EcoR1 Capital, LLC Hedge Fund•Sector | $22.0M 1.06% of portfolio |
B BAKER BROS. ADVISORS LP Hedge Fund•Sector | $17.2M 0.16% of portfolio |
B BlackRock, Inc. Institution | $16.5M 0.00% of portfolio |
 BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | $12.1M 0.03% of portfolio |
 TORONTO DOMINION BANK Institution | $11.8M 0.02% of portfolio |
 VANGUARD GROUP INC Institution | $10.5M 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for NGNE in Q3 2025
- Traded
- −$148.7K
- Buyers
- 40
- Sellers
- 36
- Total Bought
- +$21.8M
- Total Sold
- −$22.0M
- Avg Position
- $2.7M
Biggest Buyers
| Institution | Net Bought |
|---|---|
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | +$12.1M +699.0K shares |
 JENNISON ASSOCIATES LLC Long Only Manager | +$3.9M +226.5K shares |
J JANE STREET GROUP, LLC Institution | +$1.1M +62.4K shares |
 GOLDMAN SACHS GROUP INC Institution | +$961.9K +55.5K shares |
 Trexquant Investment LP Hedge Fund•Quant | +$684.2K +39.5K shares |
 ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy | +$563.6K +32.5K shares |
R Redmile Group, LLC Hedge Fund•Sector | +$387.3K +22.3K shares |
Q Quadrature Capital Ltd Institution | +$292.0K +16.8K shares |
A AMERICAN CENTURY COMPANIES INC Institution | +$236.2K +13.6K shares |
B Brevan Howard Capital Management LP Institution | +$223.2K +12.9K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 COMMODORE CAPITAL LP Hedge Fund•Long/Short | −$6.4M −427.9K shares |
 FMR LLC Institution | −$6.1M −352.9K shares |
 MORGAN STANLEY RIA/Wealth | −$2.1M −119.0K shares |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$1.0M −59.9K shares |
 BANK OF AMERICA CORP /DE/ Institution | −$950.5K −54.8K shares |
 Octagon Capital Advisors LP Hedge Fund•Sector | −$883.8K −51.0K shares |
G GREAT POINT PARTNERS LLC Private Equity | −$676.6K −39.0K shares |
 WELLINGTON MANAGEMENT CO LLP Long Only Manager | −$671.3K −44.9K shares |
 UBS OCONNOR LLC Long Only Manager | −$519.7K −34.8K shares |
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy | −$474.1K −31.7K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited NGNE in Q3 2025
- New Positions
- 7
- New Value
- $13.3M
- Exited Positions
- 10
- Exited Value
- $8.8M
New Positions
| Institution | Position Value |
|---|---|
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | $12.1M 699.0K shares |
Trexquant Investment LP Hedge Fund•Quant | $684.2K 39.5K shares |
Q Quadrature Capital Ltd Institution | $292.0K 16.8K shares |
B BRIDGEWAY CAPITAL MANAGEMENT INC Long Only Manager | $186.8K 10.8K shares |
 Point72 Ltd RIA/Wealth | $14.5K 835.0 shares |
O Optiver Holding B.V. Institution | $1.3K 76.0 shares |
 SRS Capital Advisors, Inc. RIA/Wealth | $277.0 16.0 shares |
Exited Positions
| Institution | Previous Position |
|---|---|
COMMODORE CAPITAL LP Hedge Fund•Long/Short | $6.4M 427.9K shares |
WELLINGTON MANAGEMENT CO LLP Long Only Manager | $671.3K 44.9K shares |
UBS OCONNOR LLC Long Only Manager | $519.7K 34.8K shares |
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy | $474.1K 31.7K shares |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $388.8K 26.0K shares |
H HRT FINANCIAL LLC Institution | $321.2K 21.5K shares |
 ATTICUS WEALTH MANAGEMENT, LLC RIA/Wealth | $6.5K 437.0 shares |
$6.1K 405.0 shares | |
 RAYMOND JAMES FINANCIAL INC RIA/Wealth | $120.0 8.0 shares |
 TWIN PEAKS WEALTH ADVISORS, LLC RIA/Wealth | $96.0 5.0 shares |
Options Activity
Institutions with the largest Call and Put options positions in NGNE as of Q3 2025
- Call Positions
- 2
- Call Value
- $403.8K
- Put Positions
- 1
- Put Value
- $208.0K
Call Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $403.8K 233.0 contracts |
J JANE STREET GROUP, LLC Institution | - - contracts |
Put Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $208.0K 120.0 contracts |
Most Committed Institutions
Institutions with NGNE as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
Samsara BioCapital, LLC Venture Capital | 3.89% $29.8M |
G GREAT POINT PARTNERS LLC Private Equity | 3.41% $7.7M |
R Redmile Group, LLC Hedge Fund•Sector | 2.19% $22.5M |
Casdin Capital, LLC Hedge Fund•Sector | 1.94% $22.4M |
EcoR1 Capital, LLC Hedge Fund•Sector | 1.06% $22.0M |
Octagon Capital Advisors LP Hedge Fund•Sector | 0.69% $4.4M |
RTW INVESTMENTS, LLC Hedge Fund•Sector | 0.29% $23.6M |
A Arrowpoint Asset Management, LLC Hedge Fund•Multi-Strategy | 0.19% $10.3M |
B BAKER BROS. ADVISORS LP Hedge Fund•Sector | 0.16% $17.2M |
D DAFNA Capital Management LLC Hedge Fund•Event Driven | 0.13% $526.4K |
Hedge Fund Spotlight
Discover hedge funds investing in NGNE
Rock Springs Capital Management LP
Hedge Fund • Sector
Portfolio ManagerNnamdi C Etoh
- Portfolio Value
- $1.7B
- Positions
- 91
- Last Reported
- Q3 2025
Sector Allocation
Position in Neurogene
- Market Value
- $1.8M
- Shares Held
- 104.3K
- Portfolio Weight
- 0.11%
- Owned Since
- 2024-Q4
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Unknown Unknown | $105.3M | 6.18% | |
Drug Manufacturers - General Healthcare | $80.4M | 4.72% | |
Biotechnology Healthcare | $72.4M | 4.25% |
