Schrodinger

SDGR • NASDAQ

Schrodinger is a medical - healthcare information services company in the healthcare sector on NASDAQ, led by Ramy Farid, with a market cap of $1.3B. As of Q3 2025, 95% of shares are held by 219 institutional investors, with BlackRock, Inc. as the largest holder at 12.99%.

President and Chief Executive OfficerRamy Farid

Market Cap$1.3B

Medical - Healthcare Information Services

Healthcare

Employees787.0

Websiteschrodinger.com

Country

United States of America

Overview

Overview of institutional ownership in SDGR as of Q3 2025 with a market cap of $1.5B

All Institutions

Institutions: 219
Value Held: $1.4B
Shares Held: 69.6M
Avg Position: $6.4M
Median Position: $356.8K

Hedge Funds

Hedge Funds: 24
Value Held: $201.5M
Shares Held: 10.0M
Avg Position: $8.4M
Median Position: $689.3K

Ownership Breakdown

Institutional (non-HF)

80.91%

$1.2B

Hedge Funds

13.65%

$201.5M

Retail & Other

5.44%

$80.3M

Based on market cap of $1.5B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in SDGR as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$191.8M 0.00% of portfolio	12.99% 9.6M shares	Q1 2020 Held for 5y 8m	$5.67T
B BILL & MELINDA GATES FOUNDATION TRUST Institution	-	$140.1M 0.38% of portfolio	9.49% 7.0M shares	Q1 2020 Held for 5y 8m	$36.6B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$127.2M 0.00% of portfolio	8.61% 6.3M shares	Q1 2020 Held for 5y 8m	$6.69T
R Rubric Capital Management LP Hedge Fund•Long/Short	Margaret Kossakowski CFO	$105.7M 1.52% of portfolio	7.16% 5.3M shares	Q1 2024 Held for 1y 8m	$6.9B
S Sumitomo Mitsui Trust Holdings, Inc. Institution	-	$91.4M 0.05% of portfolio	6.19% 4.6M shares	Q2 2020 Held for 5y 5m	$173.79B
UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager	James Poucher CEO	$66.3M 0.01% of portfolio	4.49% 3.3M shares	Q2 2020 Held for 5y 5m	$460.61B
Nikko Asset Management Americas, Inc. Long Only Manager	James Mark Beyer Wesley CEO	$52.9M 0.51% of portfolio	3.59% 2.6M shares	Q2 2020 Held for 5y 5m	$10.3B
LAZARD ASSET MANAGEMENT LLC Long Only Manager	Evan Lawrence Russo CEO	$47.1M 0.06% of portfolio	3.19% 2.3M shares	Q4 2020 Held for 4y 11m	$74.1B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$44.2M 0.00% of portfolio	3.00% 2.2M shares	Q1 2020 Held for 5y 8m	$2.88T
Stephens Investment Management Group LLC Long Only Manager	Joseph Warren Simpson CEO	$44.0M 0.57% of portfolio	2.98% 2.2M shares	Q4 2020 Held for 4y 11m	$7.8B

Net Capital Flow

Institutional buying and selling activity for SDGR in Q3 2025

Traded: −$23.7M
Buyers: 93
Sellers: 125
Total Bought: +$140.5M
Total Sold: −$164.2M
Avg Position: $5.5M

Biggest Buyers

Institution	Net Bought	Current Position
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$28.5M +1.4M shares	$31.1M 1.6M shares
LAZARD ASSET MANAGEMENT LLC Long Only Manager	+$18.6M +927.2K shares	$47.1M 2.3M shares
S Sumitomo Mitsui Trust Holdings, Inc. Institution	+$18.1M +904.6K shares	$91.4M 4.6M shares
MORGAN STANLEY RIA/Wealth	+$11.7M +585.1K shares	$34.9M 1.7M shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Long Only Manager	+$11.6M +577.9K shares	$41.6M 2.1M shares
TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy	+$6.5M +323.6K shares	$6.7M 336.4K shares
R Rubric Capital Management LP Hedge Fund•Long/Short	+$5.4M +268.8K shares	$105.7M 5.3M shares
GOLDMAN SACHS GROUP INC Institution	+$4.8M +241.7K shares	$11.3M 562.1K shares
JUPITER ASSET MANAGEMENT LTD Long Only Manager	+$4.7M +234.6K shares	$4.7M 234.6K shares
M Man Group plc Institution	+$2.3M +116.5K shares	$3.3M 163.2K shares

Biggest Sellers

Institution	Net Sold	Current Position
CADIAN CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	−$61.3M −3.0M shares	Sold Off 0 shares
FARALLON CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$16.5M −822.0K shares	$5.7M 284.0K shares
BANK OF AMERICA CORP /DE/ Institution	−$8.2M −408.2K shares	$4.0M 198.7K shares
UBS Group AG Institution	−$7.7M −386.2K shares	$19.1M 953.7K shares
VANGUARD GROUP INC Institution	−$5.6M −277.6K shares	$127.2M 6.3M shares
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	−$5.0M −247.4K shares	$6.8M 340.2K shares
FMR LLC Institution	−$4.8M −239.4K shares	$4.0M 197.8K shares
TOCQUEVILLE ASSET MANAGEMENT L.P. Long Only Manager	−$4.4M −219.6K shares	$3.5M 172.3K shares
B BlackRock, Inc. Institution	−$4.3M −216.0K shares	$191.8M 9.6M shares
ENVESTNET ASSET MANAGEMENT INC Long Only Manager	−$3.4M −170.1K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited SDGR in Q3 2025

New Positions: 14
New Value: $8.4M
Exited Positions: 34
Exited Value: $82.3M

New Positions

Institution	Position Value
JUPITER ASSET MANAGEMENT LTD Long Only Manager	$4.7M 234.6K shares
Connor, Clark & Lunn Investment Management Ltd. Long Only Manager	$1.8M 87.6K shares
Kestra Advisory Services, LLC RIA/Wealth	$831.7K 41.5K shares
S Sciencast Management LP Hedge Fund•Quant	$295.2K 14.7K shares
P PharVision Advisers, LLC Hedge Fund•Long/Short	$285.9K 14.3K shares
E Entropy Technologies, LP Hedge Fund•Quant Macro	$232.9K 11.6K shares
Hennion & Walsh Asset Management, Inc. RIA/Wealth	$223.0K 11.1K shares
S Salomon & Ludwin, LLC Institution	$9.8K 474.0 shares
O Optiver Holding B.V. Institution	$5.9K 293.0 shares
Union Bankshares Corp Institution	$2.1K 105.0 shares

Exited Positions

Institution	Previous Position
CADIAN CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$61.3M 3.0M shares
ENVESTNET ASSET MANAGEMENT INC Long Only Manager	$3.4M 170.1K shares
Integrated Advisors Network LLC RIA/Wealth	$2.5M 122.6K shares
J Jump Financial, LLC Institution	$1.2M 61.9K shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	$1.2M 60.8K shares
Graham Capital Management, L.P. Hedge Fund•Multi-Strategy	$1.2M 58.5K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$1.2M 57.3K shares
COMMONWEALTH EQUITY SERVICES, LLC. RIA/Wealth	$1.1M 55.7K shares
VOLORIDGE INVESTMENT MANAGEMENT, LLC Hedge Fund•Multi-Strategy	$871.5K 43.3K shares
Monaco Asset Management SAM RIA/Wealth	$804.8K 40.0K shares

Options Activity

Institutions with the largest Call and Put options positions in SDGR as of Q3 2025

Call Positions: 8
Call Value: $33.3M
Put Positions: 7
Put Value: $5.6M

Call Positions

Institution	Position Value
P PEAK6 LLC Institution	$21.9M 10.9K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$7.9M 3.9K contracts
W WOLVERINE TRADING, LLC Institution	$1.2M 574.0 contracts
J JANE STREET GROUP, LLC Institution	$940.8K 469.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$876.6K 437.0 contracts
Walleye Trading LLC RIA/Wealth	$367.1K 183.0 contracts
BARCLAYS PLC Institution	$124.4K 62.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	- - contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$2.9M 1.5K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$2.2M 1.1K contracts
J JANE STREET GROUP, LLC Institution	$292.9K 146.0 contracts
W WOLVERINE TRADING, LLC Institution	$224.4K 112.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	- - contracts
P PEAK6 LLC Institution	- - contracts
Walleye Trading LLC RIA/Wealth	- - contracts

Most Committed Institutions

Institutions with SDGR as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
R Rubric Capital Management LP Hedge Fund•Long/Short	Margaret Kossakowski CFO	1.52% $105.7M	7.16% 5.3M shares	Q1 2024 Held for 1y 8m	$6.9B
T Tejara Capital Ltd Institution	-	1.43% $2.6M	0.18% 129.7K shares	Q2 2024 Held for 1y 5m	$182.4M
PIER 88 INVESTMENT PARTNERS LLC Hedge Fund•Long/Short	Francis Thomas Timons CEO	1.15% $1.1M	0.07% 54.2K shares	Q1 2024 Held for 1y 8m	$94.4M
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	Gregory Arthur Martinez CIO	0.75% $6.8M	0.46% 340.2K shares	Q1 2020 Held for 5y 8m	$910.1M
Stephens Investment Management Group LLC Long Only Manager	Joseph Warren Simpson CEO	0.57% $44.0M	2.98% 2.2M shares	Q4 2020 Held for 4y 11m	$7.8B
Nikko Asset Management Americas, Inc. Long Only Manager	James Mark Beyer Wesley CEO	0.51% $52.9M	3.59% 2.6M shares	Q2 2020 Held for 5y 5m	$10.3B
Verity Asset Management, Inc. RIA/Wealth	Sean Jennings Mcgill President	0.43% $1.3M	0.09% 64.9K shares	Q2 2025 Held for 5 months	$304.9M
BRANDYWINE MANAGERS, LLC Fund of Funds	John Anthony Ciccarone President	0.40% $419.0K	0.03% 20.9K shares	Q1 2020 Held for 5y 8m	$104.2M
B BILL & MELINDA GATES FOUNDATION TRUST Institution	-	0.38% $140.1M	9.49% 7.0M shares	Q1 2020 Held for 5y 8m	$36.6B
ARK Investment Management LLC ETF Provider	Catherine Duddy Wood CEO	0.23% $37.6M	2.54% 1.9M shares	Q2 2020 Held for 5y 5m	$16.5B

Hedge Fund Spotlight

Discover hedge funds investing in SDGR

Parkman Healthcare Partners LLC

Hedge Fund • Long/Short

Portfolio ManagerGregory Arthur Martinez

Portfolio Value: $910.1M
Positions: 89
Last Reported: Q3 2025

Sector Allocation

Position in Schrodinger

Market Value: $6.8M
Shares Held: 340.2K
Portfolio Weight: 0.75%
Owned Since: 2020-Q1

Top Holding	Sector	Market Value	Weight
1 Boston Scientific BSX	Medical - Devices Healthcare	$42.4M	4.66%
2 Alnylam Pharmaceuticals ALNY	Biotechnology Healthcare	$40.0M	4.39%
3 Insulet PODD	Medical - Devices Healthcare	$35.9M	3.94%