Silence Therapeutics is a publicly traded company on NASDAQ. As of Q3 2025, 47 institutional investors hold shares in this company, with total holdings valued at $94.7M. TCG Crossover Management, LLC is the largest holder with a position valued at $15.7M.
Overview of institutional ownership in SLN as of Q3 2025
Institutions with the largest positions in SLN as of Q3 2025
| Institution | Position Value |
|---|---|
TCG Crossover Management, LLC Venture Capital | $15.7M 0.79% of portfolio |
S Siren, L.L.C. Institution | $15.1M 0.63% of portfolio |
R Redmile Group, LLC Hedge Fund•Sector | $11.2M 1.09% of portfolio |
L Lombard Odier Asset Management Corp Hedge Fund•Multi-Strategy | $7.1M 1.87% of portfolio |
MORGAN STANLEY RIA/Wealth | $6.3M 0.00% of portfolio |
Vivo Capital, LLC Venture Capital | $5.7M 0.46% of portfolio |
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy | $5.4M 0.33% of portfolio |
Frazier Life Sciences Management, L.P. Venture Capital | $5.0M 0.15% of portfolio |
N Nextech Invest, Ltd. Institution | $4.9M 0.75% of portfolio |
C CANTOR FITZGERALD, L. P. Institution | $4.2M 0.08% of portfolio |
Institutional buying and selling activity for SLN in Q3 2025
| Institution | Net Bought |
|---|---|
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | +$518.3K +99.9K shares |
UBS Group AG Institution | +$409.3K +78.9K shares |
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | +$141.3K +27.2K shares |
GOLDMAN SACHS GROUP INC Institution | +$117.5K +22.6K shares |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | +$111.6K +21.5K shares |
C CANTOR FITZGERALD, L. P. Institution | +$63.7K +12.3K shares |
E EHP Funds Inc. Institution | +$55.4K +10.7K shares |
BANK OF MONTREAL /CAN/ Institution | +$41.4K +8.0K shares |
Ikarian Capital, LLC Hedge Fund•Event Driven | +$39.5K +27.2K shares |
BARCLAYS PLC Institution | +$37.0K +101.0 shares |
| Institution | Net Sold |
|---|---|
B BlackRock, Inc. Institution | −$552.2K −106.4K shares |
Marshall Wace LLP Institution | −$480.8K −92.6K shares |
J JANE STREET GROUP, LLC Institution | −$219.3K −37.8K shares |
S Saturn V Capital Management LLC Hedge Fund•Sector | −$201.5K −34.7K shares |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | −$161.2K −27.8K shares |
M Massar Capital Management, LP Institution | −$115.2K −19.9K shares |
R Rathbone Brothers plc RIA/Wealth | −$106.8K −18.4K shares |
Beacon Pointe Advisors, LLC RIA/Wealth | −$67.4K −11.6K shares |
A Advisor Group Holdings, Inc. Institution | −$34.7K −7.2K shares |
MORGAN STANLEY RIA/Wealth | −$20.9K −4.0K shares |
Institutions that initiated new positions or completely exited SLN in Q3 2025
| Institution | Position Value |
|---|---|
E EHP Funds Inc. Institution | $55.4K 10.7K shares |
BARCLAYS PLC Institution | $37.0K 7.1K shares |
Rockefeller Capital Management L.P. Long Only Manager | $234.0 45.0 shares |
| Institution | Previous Position |
|---|---|
J JANE STREET GROUP, LLC Institution | $219.3K 37.8K shares |
S Saturn V Capital Management LLC Hedge Fund•Sector | $201.5K 34.7K shares |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $161.2K 27.8K shares |
M Massar Capital Management, LP Institution | $115.2K 19.9K shares |
R Rathbone Brothers plc RIA/Wealth | $106.8K 18.4K shares |
Beacon Pointe Advisors, LLC RIA/Wealth | $67.4K 11.6K shares |
E EverSource Wealth Advisors, LLC RIA/Wealth | $58.0 10.0 shares |
Institutions with the largest Call and Put options positions in SLN as of Q3 2025
| Institution | Position Value |
|---|---|
J JANE STREET GROUP, LLC Institution | - - contracts |
| Institution | Position Value |
|---|---|
| No put positions found | |
Institutions with SLN as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
L Lombard Odier Asset Management Corp Hedge Fund•Multi-Strategy | 1.87% $7.1M |
M28 Capital Management LP Hedge Fund•Long/Short | 1.41% $960.7K |
R Redmile Group, LLC Hedge Fund•Sector | 1.09% $11.2M |
5 5AM Venture Management, LLC Institution | 0.91% $2.5M |
TCG Crossover Management, LLC Venture Capital | 0.79% $15.7M |
N Nextech Invest, Ltd. Institution | 0.75% $4.9M |
S Siren, L.L.C. Institution | 0.63% $15.1M |
Vivo Capital, LLC Venture Capital | 0.46% $5.7M |
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy | 0.33% $5.4M |
Ikarian Capital, LLC Hedge Fund•Event Driven | 0.26% $1.3M |
Discover hedge funds investing in SLN

| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
ETF ETF | $5.0B | 4.11% | |
Semiconductors Technology | $3.4B | 2.80% | |
Consumer Electronics Technology | $1.8B | 1.46% |
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