ORBIMED ADVISORS LLC Portfolio Holdings
Q3 2025•96 long positions•$4.1B portfolio value
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Holding111 | Sector | Position↕ | Traded↕ | Ownership↕ | Shares Δ↕ | Shares Δ % | Market Cap↕ | Owned Since↕ |
|---|---|---|---|---|---|---|---|---|
Biotechnology Healthcare | $251.7M 6.11% | — | 14.73% 15.5M shares | — | — | $1.7B Small Cap | Q1 2021 Held for 4y 8m | |
Medical - Devices Healthcare | $237.2M 5.75% | -$37.5M Sold | 0.164% 2.4M shares | 2.8M → 2.4M −$37.5M | -13.65% | $144.66B Large Cap | Q3 2013 Held for 12y 2m | |
Drug Manufacturers - General Healthcare | $229.8M 5.57% | -$27.8M Sold | 0.034% 301.2K shares | 337.6K → 301.2K −$27.8M | -10.78% | $684.00B Mega Cap | Q3 2022 Held for 3y 2m | |
Biotechnology Healthcare | $184.5M 4.47% | — | — 2.7M shares | — | — | — — | ≤ Q2 2013 Held for 12y 5m+ | |
Biotechnology Healthcare | $162.9M 3.95% | — | 13.44% 8.0M shares | — | — | $1.2B Small Cap | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $137.5M 3.34% | -$18.4M Sold | 0.23% 301.6K shares | 341.9K → 301.6K −$18.4M | -11.79% | $59.8B Large Cap | Q4 2023 Held for 1y 11m | |
Medical - Devices Healthcare | $132.8M 3.22% | — | 0.094% 359.2K shares | — | — | $141.33B Large Cap | Q1 2020 Held for 5y 8m | |
Medical - Devices Healthcare | $131.0M 3.18% | -$1.9M Sold | 0.287% 1.7M shares | 1.7M → 1.7M −$1.9M | -1.41% | $45.7B Large Cap | Q4 2024 Held for 11 months | |
Medical - Instruments & Supplies Healthcare | $128.4M 3.12% | -$1.7M Sold | 0.08% 287.2K shares | 291.0K → 287.2K −$1.7M | -1.31% | $160.32B Large Cap | Q4 2013 Held for 11y 11m | |
Unknown Unknown | $127.1M 3.08% | -$26.3M Sold | — 172.3K shares | 208.0K → 172.3K −$26.3M | -17.16% | — — | Q4 2022 Held for 2y 11m | |
Unknown Unknown | $109.0M 2.64% | — | 8.39% 3.7M shares | — | — | $1.3B Small Cap | Q1 2025 Held for 8 months | |
Unknown Unknown | $107.1M 2.6% | — | 10.56% 5.7M shares | — | — | $1.0B Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $93.5M 2.27% | — | 4.07% 1.4M shares | — | — | $2.3B Mid Cap | Q4 2022 Held for 2y 11m | |
Unknown Unknown | $91.8M 2.23% | — | — 3.0M shares | — | — | — — | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $83.3M 2.02% | — | 8.39% 8.3M shares | — | — | $993.2M Small Cap | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $71.4M 1.73% | -$7.6M Sold | 1.12% 1.6M shares | 1.8M → 1.6M −$7.6M | -9.6% | $6.4B Mid Cap | Q1 2024 Held for 1y 8m | |
Unknown Unknown | $70.1M 1.7% | — | 8.95% 4.0M shares | — | — | $782.5M Small Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $69.6M 1.69% | -$6.1M Sold | 2.26% 1.7M shares | 1.9M → 1.7M −$6.1M | -8.04% | $3.1B Mid Cap | Q3 2024 Held for 1y 2m | |
Medical - Diagnostics & Research Healthcare | $69.1M 1.68% | -$26.4M Sold | 0.313% 429.3K shares | 593.4K → 429.3K −$26.4M | -27.66% | $22.1B Large Cap | Q3 2015 Held for 10y 2m | |
Biotechnology Healthcare | $64.6M 1.57% | +$12.6M Bought | 1.07% 531.8K shares | 427.9K → 531.8K +$12.6M | +24.28% | $6.1B Mid Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $56.8M 1.38% | — | 8.64% 7.6M shares | — | — | $657.2M Small Cap | Q1 2021 Held for 4y 8m | |
Biotechnology Healthcare | $55.9M 1.35% | — | 7.46% 3.0M shares | — | — | $748.5M Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $55.7M 1.35% | +$26.9M Bought | 1.89% 1.5M shares | 760.4K → 1.5M +$26.9M | +93.27% | $2.9B Mid Cap | Q1 2024 Held for 1y 8m | |
Medical - Diagnostics & Research Healthcare | $54.4M 1.32% | +$21.2M Bought | 0.525% 994.6K shares | 607.3K → 994.6K +$21.2M | +63.77% | $10.4B Large Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $53.3M 1.29% | — | 8.87% 15.2M shares | — | — | $600.5M Small Cap | Q4 2021 Held for 3y 11m | |
Biotechnology Healthcare | $52.8M 1.28% | — | 9.62% 7.2M shares | — | — | $549.2M Small Cap | Q1 2016 Held for 9y 8m | |
Biotechnology Healthcare | $52.6M 1.28% | +$19.0M Bought | 1.84% 2.3M shares | 1.5M → 2.3M +$19.0M | +56.74% | $2.9B Mid Cap | Q1 2023 Held for 2y 8m | |
Medical - Diagnostics & Research Healthcare | $52.2M 1.27% | +$52.2M Bought | 0.037% 263.1K shares | — | — | $141.96B Large Cap | Q3 2025 Held for 2 months | |
Drug Manufacturers - Specialty & Generic Healthcare | $49.6M 1.2% | -$11.9M Sold | 0.357% 353.6K shares | 438.5K → 353.6K −$11.9M | -19.36% | $13.9B Large Cap | ≤ Q2 2013 Held for 12y 5m+ | |
Biotechnology Healthcare | $48.2M 1.17% | +$48.2M Bought | 0.254% 114.9K shares | — | — | $19.0B Large Cap | Q3 2025 Held for 2 months | |
Medical - Healthcare Plans Healthcare | $46.9M 1.14% | +$46.9M Bought | 0.061% 162.8K shares | — | — | $76.9B Large Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $45.8M 1.11% | -$2.1M Sold | 1.17% 1.1M shares | 1.1M → 1.1M −$2.1M | -4.35% | $3.9B Mid Cap | Q3 2018 Held for 7y 2m | |
Biotechnology Healthcare | $43.7M 1.06% | +$32.9M Bought | 3.75% 3.6M shares | 899.3K → 3.6M +$32.9M | +304.96% | $1.2B Small Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $43.2M 1.05% | +$13.6M Bought | 2.94% 1.8M shares | 1.2M → 1.8M +$13.6M | +45.92% | $1.5B Small Cap | Q2 2021 Held for 4y 5m | |
Biotechnology Healthcare | $41.1M 0.996% | -$977.8K Sold | 0.398% 2.7M shares | 2.8M → 2.7M −$977.8K | -2.33% | $10.3B Large Cap | Q2 2025 Held for 5 months | |
Unknown Unknown | $38.2M 0.926% | +$31.3M Bought | — 191.9K shares | 34.4K → 191.9K +$31.3M | +457.86% | — — | Q2 2025 Held for 5 months | |
Medical - Devices Healthcare | $38.0M 0.921% | — | 5.98% 2.6M shares | — | — | $635.0M Small Cap | Q4 2018 Held for 6y 11m | |
Biotechnology Healthcare | $34.4M 0.833% | — | 11.29% 6.1M shares | — | — | $304.4M Small Cap | Q4 2017 Held for 7y 11m | |
Unknown Unknown | $31.9M 0.774% | -$1.7M Sold | — 1.1M shares | 1.2M → 1.1M −$1.7M | -5.0% | — — | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $30.3M 0.734% | — | 2.72% 3.3M shares | — | — | $1.1B Small Cap | Q1 2025 Held for 8 months | |
Medical - Devices Healthcare | $30.0M 0.727% | -$14.8M Sold | 0.828% 290.0K shares | 433.4K → 290.0K −$14.8M | -33.09% | $3.6B Mid Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $29.3M 0.71% | +$16.2M Bought | 1.63% 2.3M shares | 1.0M → 2.3M +$16.2M | +124.37% | $1.8B Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $28.0M 0.68% | -$14.3M Sold | 6.57% 1.1M shares | 1.6M → 1.1M −$14.3M | -33.82% | $426.5M Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $27.0M 0.655% | — | 5.13% 8.5M shares | — | — | $526.1M Small Cap | Q2 2025 Held for 5 months | |
Medical - Devices Healthcare | $27.0M 0.654% | — | 7.9% 2.6M shares | — | — | $341.1M Small Cap | Q2 2021 Held for 4y 5m | |
Biotechnology Healthcare | $26.8M 0.649% | +$26.8M Bought | 0.744% 458.5K shares | — | — | $3.6B Mid Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $25.6M 0.62% | +$25.6M Bought | 2.61% 1.8M shares | — | — | $981.5M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $25.0M 0.606% | +$15.0M Bought | 0.658% 526.2K shares | 211.3K → 526.2K +$15.0M | +149.03% | $3.8B Mid Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $23.6M 0.573% | — | 5.25% 5.9M shares | — | — | $450.0M Small Cap | Q2 2024 Held for 1y 5m | |
Medical - Diagnostics & Research Healthcare | $22.6M 0.547% | — | 0.012% 46.5K shares | — | — | $183.15B Large Cap | ≤ Q2 2013 Held for 12y 5m+ |
