Akero Therapeutics
AKRO • NASDAQ
Akero Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by Andrew Cheng, with a market cap of $4.5B. As of Q3 2025, 114% of shares are held by 256 institutional investors, with HENDERSON GROUP PLC as the largest holder at 7.85%.
Chief Executive OfficerAndrew Cheng
Market Cap$4.5B
Biotechnology
Healthcare
Employees58.0
Websiteakerotx.com
Country
United States of America
Overview
Overview of institutional ownership in AKRO as of Q3 2025 with a market cap of $3.8B
All Institutions
- Institutions
- 256
- Value Held
- $4.3B
- Shares Held
- 91.4M
- Avg Position
- $16.9M
- Median Position
- $1.3M
Hedge Funds
- Hedge Funds
- 59
- Value Held
- $1.3B
- Shares Held
- 26.9M
- Avg Position
- $21.6M
- Median Position
- $8.5M
Ownership Breakdown
Based on market cap of $3.8B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in AKRO as of Q3 2025
| Institution | Position Value |
|---|---|
 HENDERSON GROUP PLC Institution | $298.2M 0.14% of portfolio |
G GENERAL ATLANTIC LLC Institution | $272.2M 8.17% of portfolio |
B BlackRock, Inc. Institution | $270.8M 0.00% of portfolio |
 RTW INVESTMENTS, LLC Hedge Fund•Sector | $260.1M 3.23% of portfolio |
 VANGUARD GROUP INC Institution | $214.9M 0.00% of portfolio |
 WELLINGTON MANAGEMENT CO LLP Long Only Manager | $201.9M 0.04% of portfolio |
 Deep Track Capital, LP Hedge Fund•Long/Short | $190.0M 5.40% of portfolio |
 venBio Select Advisor LLC RIA/Wealth | $187.8M 2.43% of portfolio |
 PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager | $180.9M 0.02% of portfolio |
 STATE STREET CORP Institution | $162.1M 0.01% of portfolio |
Net Capital Flow
Institutional buying and selling activity for AKRO in Q3 2025
- Net Flow
- −$154.3M
- Buyers
- 83
- Sellers
- 124
- Total Bought
- +$372.0M
- Total Sold
- −$526.2M
- Avg Position
- $16.3M
Biggest Buyers
| Institution | Net Bought |
|---|---|
Deep Track Capital, LP Hedge Fund•Long/Short | +$45.5M +958.4K shares |
WELLINGTON MANAGEMENT CO LLP Long Only Manager | +$40.0M +841.9K shares |
STATE STREET CORP Institution | +$31.8M +668.7K shares |
A AMERICAN CENTURY COMPANIES INC Institution | +$31.5M +663.4K shares |
 Weiss Asset Management LP Hedge Fund•Multi-Strategy | +$21.7M +457.5K shares |
venBio Select Advisor LLC RIA/Wealth | +$21.6M +455.6K shares |
B Bellevue Group AG Institution | +$19.2M +404.0K shares |
 ORBIMED ADVISORS LLC Hedge Fund•Sector | +$15.0M +314.9K shares |
F First Turn Management, LLC Hedge Fund•Long/Short | +$13.4M +282.5K shares |
 DIMENSIONAL FUND ADVISORS LP Long Only Manager | +$11.2M +236.9K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 Woodline Partners LP Hedge Fund•Long/Short | −$86.8M −1.8M shares |
 UBS Group AG Institution | −$80.4M −1.7M shares |
 Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | −$49.7M −1.0M shares |
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager | −$33.2M −699.5K shares |
 EcoR1 Capital, LLC Hedge Fund•Sector | −$23.5M −440.0K shares |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | −$23.0M −483.8K shares |
HENDERSON GROUP PLC Institution | −$21.8M −458.3K shares |
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy | −$19.1M −403.0K shares |
S Siren, L.L.C. Institution | −$17.0M −318.6K shares |
 MORGAN STANLEY RIA/Wealth | −$16.8M −353.3K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited AKRO in Q3 2025
- New Positions
- 22
- New Value
- $82.2M
- Exited Positions
- 35
- Exited Value
- $83.8M
New Positions
| Institution | Position Value |
|---|---|
 Polar Capital Holdings Plc Long Only Manager | $50.3M 1.1M shares |
 CenterBook Partners LP Hedge Fund•Market Neutral | $8.8M 185.6K shares |
 Hood River Capital Management LLC Long Only Manager | $8.5M 178.5K shares |
C Capricorn Fund Managers Ltd Institution | $7.1M 149.2K shares |
N NATIXIS Institution | $2.5M 52.9K shares |
 Prosight Management, LP Hedge Fund•Long/Short | $1.9M 39.1K shares |
R ROYCE & ASSOCIATES LLC Institution | $1.5M 32.5K shares |
 Lighthouse Investment Partners, LLC Fund of Funds | $949.6K 20.0K shares |
P PharVision Advisers, LLC Hedge Fund•Long/Short | $238.2K 5.0K shares |
 Empirical Financial Services, LLC RIA/Wealth | $209.3K 4.4K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
EcoR1 Capital, LLC Hedge Fund•Sector | $23.5M 440.0K shares |
S Siren, L.L.C. Institution | $17.0M 318.6K shares |
A ADAGE CAPITAL PARTNERS GP LLC Institution | $15.7M 295.0K shares |
 BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | $5.1M 96.4K shares |
C CI Private Wealth, LLC RIA/Wealth | $3.9M 73.6K shares |
A AXA Institution | $3.8M 71.0K shares |
J J. Goldman & Co LP Hedge Fund•Multi-Strategy | $3.5M 65.6K shares |
 Connor, Clark & Lunn Investment Management Ltd. Long Only Manager | $2.2M 41.3K shares |
T TWINBEECH CAPITAL LP Hedge Fund•Quant | $1.4M 26.0K shares |
B Brevan Howard Capital Management LP Institution | $1.3M 23.4K shares |
Options Activity
Institutions with the largest Call and Put options positions in AKRO as of Q3 2025
- Call Positions
- 21
- Call Value
- $50.0M
- Put Positions
- 14
- Put Value
- $15.9M
Call Positions
| Institution | Position Value |
|---|---|
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | $23.7M 5.0K contracts |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $11.7M 2.5K contracts |
 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC Hedge Fund•Long/Short | $3.9M 822.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $2.0M 419.0 contracts |
 Ikarian Capital, LLC Hedge Fund•Event Driven | $2.0M 416.0 contracts |
 Caption Management, LLC Hedge Fund•Long/Short | $1.4M 300.0 contracts |
J JANE STREET GROUP, LLC Institution | $830.9K 175.0 contracts |
 TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy | $750.2K 158.0 contracts |
 BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | $716.9K 151.0 contracts |
 Centiva Capital, LP Hedge Fund•Multi-Strategy | $712.2K 150.0 contracts |
Put Positions
| Institution | Position Value |
|---|---|
Caption Management, LLC Hedge Fund•Long/Short | $6.2M 1.3K contracts |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $4.2M 894.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $2.6M 557.0 contracts |
J JANE STREET GROUP, LLC Institution | $1.5M 317.0 contracts |
TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy | $735.9K 155.0 contracts |
W WOLVERINE TRADING, LLC Institution | $352.4K 74.0 contracts |
 Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy | $109.2K 23.0 contracts |
 Walleye Trading LLC RIA/Wealth | $80.7K 17.0 contracts |
 StemPoint Capital LP Hedge Fund•Long/Short | $9.7K 155.0 contracts |
 Hunting Hill Global Capital, LLC Hedge Fund•Multi-Strategy | - - contracts |
Most Committed Institutions
Institutions with AKRO as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
 University of Wisconsin Foundation RIA/Wealth | 13.21% $15.6M |
B B Group, Inc. Institution | 12.75% $11.0M |
 Propel Bio Management, LLC Hedge Fund•Sector | 10.88% $10.9M |
G GENERAL ATLANTIC LLC Institution | 8.17% $272.2M |
 Logos Global Management LP Hedge Fund•Long/Short | 5.77% $57.0M |
Deep Track Capital, LP Hedge Fund•Long/Short | 5.40% $190.0M |
 Foresite Capital Management VI LLC Venture Capital | 4.49% $11.6M |
 SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | 4.43% $30.6M |
R Redmile Group, LLC Hedge Fund•Sector | 3.45% $35.5M |
RTW INVESTMENTS, LLC Hedge Fund•Sector | 3.23% $260.1M |
Hedge Fund Spotlight
Discover hedge funds investing in AKRO
YIHENG CAPITAL LLC
Hedge Fund • Long/Short
Portfolio ManagerYuanshan Guo
- Portfolio Value
- $297.8M
- Positions
- 22
- Last Reported
- Q3 2025
Sector Allocation
Position in Akero Therapeutics
- Market Value
- $9.1M
- Shares Held
- 191.1K
- Portfolio Weight
- 3.05%
- Owned Since
- 2021-Q1
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Unknown Unknown | $77.9M | 26.14% | |
Unknown Unknown | $39.8M | 13.38% | |
Unknown Unknown | $27.7M | 9.30% |
