enGene Holdings Inc.

ENGN • NASDAQ

enGene Holdings Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Ronald H. W. Cooper, with a market cap of $565.7M. As of Q3 2025, 80% of shares are held by 39 institutional investors, with FCPM III SERVICES B.V. as the largest holder at 18.82%.

Chief Executive OfficerRonald H. W. Cooper

Market Cap$565.7M

Biotechnology

Healthcare

Employees33.0

Websiteengene.com

Country

United States of America

Overview

Overview of institutional ownership in ENGN as of Q3 2025 with a market cap of $349.6M

All Institutions

Institutions: 39
Value Held: $279.1M
Shares Held: 40.9M
Avg Position: $7.2M
Median Position: $2.3M

Hedge Funds

Hedge Funds: 12
Value Held: $107.2M
Shares Held: 15.7M
Avg Position: $8.9M
Median Position: $5.4M

Ownership Breakdown

Institutional (non-HF)

49.18%

$172.0M

Hedge Funds

30.65%

$107.2M

Retail & Other

20.17%

$70.5M

Based on market cap of $349.6M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in ENGN as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
FCPM III SERVICES B.V. Real Assets	Andrew David Lindner Managing Partner	$65.8M 13.15% of portfolio	18.82% 9.6M shares	Q4 2023 Held for 1y 11m	$500.4M
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	$34.5M 1.94% of portfolio	9.86% 5.0M shares	Q1 2024 Held for 1y 8m	$1.8B
K Kynam Capital Management, LP Hedge Fund•Long/Short	Jared Joseph Keller COO	$34.1M 2.54% of portfolio	9.76% 5.0M shares	Q3 2024 Held for 1y 2m	$1.3B
B Blue Owl Capital Holdings LP Institution	-	$22.4M 7.02% of portfolio	6.40% 3.3M shares	Q4 2023 Held for 1y 11m	$318.8M
C Cormorant Asset Management, LLC Hedge Fund•Long/Short	Bihua Chen CEO	$15.9M 1.24% of portfolio	4.54% 2.3M shares	Q1 2024 Held for 1y 8m	$1.3B
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	$15.5M 0.63% of portfolio	4.43% 2.3M shares	Q3 2025 Held for 2 months	$2.5B
Deep Track Capital, LP Hedge Fund•Long/Short	David Eric Kroin CIO	$15.3M 0.43% of portfolio	4.37% 2.2M shares	Q1 2024 Held for 1y 8m	$3.5B
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short	Joseph Eric Edelman CEO	$14.3M 0.41% of portfolio	4.10% 2.1M shares	Q3 2025 Held for 2 months	$3.5B
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	Steven Alan Cohen CEO	$8.3M 0.02% of portfolio	2.36% 1.2M shares	Q1 2024 Held for 1y 8m	$43.2B
Frazier Life Sciences Management, L.P. Venture Capital	James Newman Topper Managing Partner	$7.9M 0.24% of portfolio	2.26% 1.2M shares	Q3 2025 Held for 2 months	$3.3B

Net Capital Flow

Institutional buying and selling activity for ENGN in Q3 2025

Traded: +$5.4M
Buyers: 14
Sellers: 14
Total Bought: +$42.5M
Total Sold: −$37.1M
Avg Position: $6.2M

Biggest Buyers

Institution	Net Bought	Current Position
B BRAIDWELL LP Hedge Fund•Multi-Strategy	+$15.5M +2.3M shares	$15.5M 2.3M shares
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short	+$14.3M +2.1M shares	$14.3M 2.1M shares
Frazier Life Sciences Management, L.P. Venture Capital	+$7.9M +1.2M shares	$7.9M 1.2M shares
MPM Oncology Impact Management LP Institution	+$3.6M +530.3K shares	$3.6M 530.3K shares
MORGAN STANLEY RIA/Wealth	+$563.6K +82.5K shares	$3.0M 435.3K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$241.3K +35.3K shares	$398.7K 58.4K shares
WELLS FARGO & COMPANY/MN Institution	+$100.5K +14.7K shares	$122.3K 17.9K shares
Hudson Bay Capital Management LP Hedge Fund•Multi-Strategy	+$75.6K +11.1K shares	$75.6K 11.1K shares
PFS Partners, LLC RIA/Wealth	+$61.5K +9.0K shares	$61.5K 9.0K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	+$54.2K +7.9K shares	$68.3K 10.0K shares

Biggest Sellers

Institution	Net Sold	Current Position
Deep Track Capital, LP Hedge Fund•Long/Short	−$15.8M −2.3M shares	$15.3M 2.2M shares
BANK OF AMERICA CORP /DE/ Institution	−$9.3M −1.4M shares	$4.4M 647.2K shares
GOLDMAN SACHS GROUP INC Institution	−$5.1M −751.5K shares	$1.0M 147.6K shares
B Blue Owl Capital Holdings LP Institution	−$3.1M −450.0K shares	$22.4M 3.3M shares
ORBIMED ADVISORS LLC Hedge Fund•Sector	−$2.5M −678.0K shares	Sold Off 0 shares
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy	−$1.0M −149.5K shares	$171.2K 25.1K shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	−$101.1K −27.8K shares	Sold Off 0 shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	−$41.5K −11.4K shares	Sold Off 0 shares
SUNRISE PARTNERS LIMITED PARTNERSHIP /CT Hedge Fund•Multi-Strategy	−$37.6K −10.3K shares	Sold Off 0 shares
TORONTO DOMINION BANK Institution	−$31.0K −4.5K shares	$68.3K 10.0K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited ENGN in Q3 2025

New Positions: 5
New Value: $27.1M
Exited Positions: 6
Exited Value: $2.7M

New Positions

Institution	Position Value
B BRAIDWELL LP Hedge Fund•Multi-Strategy	$15.5M 2.3M shares
Frazier Life Sciences Management, L.P. Venture Capital	$7.9M 1.2M shares
MPM Oncology Impact Management LP Institution	$3.6M 530.3K shares
Hudson Bay Capital Management LP Hedge Fund•Multi-Strategy	$75.6K 11.1K shares
PFS Partners, LLC RIA/Wealth	$61.5K 9.0K shares

Exited Positions

Institution	Previous Position
ORBIMED ADVISORS LLC Hedge Fund•Sector	$2.5M 678.0K shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	$101.1K 27.8K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	$41.5K 11.4K shares
SUNRISE PARTNERS LIMITED PARTNERSHIP /CT Hedge Fund•Multi-Strategy	$37.6K 10.3K shares
WOLVERINE ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$23.2K 6.4K shares
NBC SECURITIES, INC. RIA/Wealth	$1.0K 380.0 shares

Options Activity

Institutions with the largest Call and Put options positions in ENGN as of Q3 2025

Call Positions: 0
Call Value: -
Put Positions: 0
Put Value: -

Call Positions

Institution	Position Value
No call positions found

Put Positions

Institution	Position Value
No put positions found

Most Committed Institutions

Institutions with ENGN as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
FCPM III SERVICES B.V. Real Assets	Andrew David Lindner Managing Partner	13.15% $65.8M	18.82% 9.6M shares	Q4 2023 Held for 1y 11m	$500.4M
B Blue Owl Capital Holdings LP Institution	-	7.02% $22.4M	6.40% 3.3M shares	Q4 2023 Held for 1y 11m	$318.8M
K Kynam Capital Management, LP Hedge Fund•Long/Short	Jared Joseph Keller COO	2.54% $34.1M	9.76% 5.0M shares	Q3 2024 Held for 1y 2m	$1.3B
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	1.94% $34.5M	9.86% 5.0M shares	Q1 2024 Held for 1y 8m	$1.8B
Omega Fund Management Inc. Venture Capital	Alexandra Rankel Pearsall CFO	1.62% $3.6M	1.03% 526.4K shares	Q4 2023 Held for 1y 11m	$222.4M
C Cormorant Asset Management, LLC Hedge Fund•Long/Short	Bihua Chen CEO	1.24% $15.9M	4.54% 2.3M shares	Q1 2024 Held for 1y 8m	$1.3B
S SPHERA FUNDS MANAGEMENT LTD. Institution	-	0.83% $3.4M	0.99% 504.4K shares	Q4 2024 Held for 11 months	$416.3M
SR ONE CAPITAL MANAGEMENT, LP Venture Capital	Simeon John George CEO	0.74% $5.1M	1.46% 747.8K shares	Q2 2024 Held for 1y 5m	$691.4M
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	0.63% $15.5M	4.43% 2.3M shares	Q3 2025 Held for 2 months	$2.5B
MPM Oncology Impact Management LP Institution	Christian Albrecht Wulf Von Schimmelmann Managing Partner	0.59% $3.6M	1.04% 530.3K shares	Q3 2025 Held for 2 months	$610.9M

Hedge Fund Spotlight

Discover hedge funds investing in ENGN

Deep Track Capital, LP

Hedge Fund • Long/Short

Portfolio ManagerDavid Eric Kroin

Portfolio Value: $3.5B
Positions: 55
Last Reported: Q3 2025

Sector Allocation

Position in enGene Holdings Inc.

Market Value: $15.3M
Shares Held: 2.2M
Portfolio Weight: 0.43%
Owned Since: 2024-Q1

Top Holding	Sector	Market Value	Weight
1 Guardant Health GH	Medical - Diagnostics & Research Healthcare	$259.5M	7.38%
2 Ionis Pharmaceuticals IONS	Biotechnology Healthcare	$249.1M	7.08%
3 Cytokinetics CYTK	Biotechnology Healthcare	$236.3M	6.72%