Innoviva, Inc.

INVA • NASDAQ

Innoviva, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Geoffrey Hulme, with a market cap of $1.5B. As of Q3 2025, 120% of shares are held by 256 institutional investors, with BlackRock, Inc. as the largest holder at 14.97%.

Interim Principal Executive OfficerGeoffrey Hulme

Market Cap$1.5B

Biotechnology

Healthcare

Employees112.0

Websiteinva.com

Country

United States of America

Overview

Overview of institutional ownership in INVA as of Q3 2025 with a market cap of $1.2B

All Institutions

Institutions: 256
Value Held: $1.4B
Shares Held: 75.5M
Avg Position: $5.4M
Median Position: $500.4K

Hedge Funds

Hedge Funds: 30
Value Held: $289.3M
Shares Held: 15.9M
Avg Position: $9.6M
Median Position: $1.9M

Ownership Breakdown

Institutional (non-HF)

94.66%

$1.1B

Hedge Funds

25.15%

$289.3M

Retail & Other

Based on market cap of $1.2B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in INVA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$172.2M 0.00% of portfolio	14.97% 9.4M shares	≤ Q2 2013 Held for 12y 5m+	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$129.5M 0.00% of portfolio	11.26% 7.1M shares	≤ Q2 2013 Held for 12y 5m+	$6.69T
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	$83.7M 0.11% of portfolio	7.28% 4.6M shares	Q1 2017 Held for 8y 8m	$75.8B
DIMENSIONAL FUND ADVISORS LP Long Only Manager	David Paul Butler CEO	$79.0M 0.02% of portfolio	6.87% 4.3M shares	Q2 2016 Held for 9y 5m	$466.32B
Sarissa Capital Management LP Hedge Fund•Activist	Alexander John Denner CEO	$51.4M 28.49% of portfolio	4.47% 2.8M shares	Q3 2016 Held for 9y 2m	$180.4M
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$46.7M 0.00% of portfolio	4.06% 2.6M shares	≤ Q2 2013 Held for 12y 5m+	$2.88T
FRANKLIN RESOURCES INC Institution	Gregory E. Johnson CEO	$45.6M 0.01% of portfolio	3.96% 2.5M shares	Q3 2020 Held for 5y 2m	$395.36B
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	Anthony Ryan CEO	$43.0M 0.03% of portfolio	3.74% 2.4M shares	Q3 2017 Held for 8y 2m	$158.92B
A AMERICAN CENTURY COMPANIES INC Institution	-	$42.9M 0.02% of portfolio	3.73% 2.4M shares	Q2 2016 Held for 9y 5m	$195.93B
SYSTEMATIC FINANCIAL MANAGEMENT LP Long Only Manager	Kenneth Burgess CIO	$38.6M 0.94% of portfolio	3.36% 2.1M shares	Q2 2021 Held for 4y 5m	$4.1B

Net Capital Flow

Institutional buying and selling activity for INVA in Q3 2025

Traded: +$37.9M
Buyers: 134
Sellers: 123
Total Bought: +$143.3M
Total Sold: −$105.5M
Avg Position: $4.7M

Biggest Buyers

Institution	Net Bought	Current Position
Weiss Asset Management LP Hedge Fund•Multi-Strategy	+$13.4M +733.4K shares	$14.0M 768.9K shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	+$11.9M +650.2K shares	$43.0M 2.4M shares
Robeco Investment Management, Inc. Long Only Manager	+$10.2M +556.5K shares	$26.1M 1.4M shares
D DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main Institution	+$8.1M +443.7K shares	$8.2M 450.5K shares
R ROYCE & ASSOCIATES LLC Institution	+$8.0M +437.7K shares	$9.2M 505.9K shares
Q Qube Research & Technologies Ltd Institution	+$7.6M +414.9K shares	$18.7M 1.0M shares
UBS Group AG Institution	+$5.8M +320.5K shares	$10.4M 572.4K shares
B BlackRock, Inc. Institution	+$5.8M +320.4K shares	$172.2M 9.4M shares
Marshall Wace LLP Institution	+$5.8M +318.7K shares	$30.1M 1.7M shares
N Nuveen, LLC Institution	+$5.8M +318.4K shares	$25.4M 1.4M shares

Biggest Sellers

Institution	Net Sold	Current Position
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$8.2M −451.2K shares	$18.0M 987.0K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$6.4M −348.0K shares	$30.0M 1.6M shares
FRANKLIN RESOURCES INC Institution	−$6.0M −330.1K shares	$45.6M 2.5M shares
Allspring Global Investments Holdings, LLC Long Only Manager	−$5.9M −292.2K shares	Sold Off 0 shares
D D. E. Shaw & Co., Inc. Institution	−$5.2M −285.9K shares	$13.4M 735.7K shares
GOLDMAN SACHS GROUP INC Institution	−$4.9M −266.0K shares	$22.0M 1.2M shares
DENALI ADVISORS LLC Long Only Manager	−$4.7M −255.5K shares	$1.4M 77.2K shares
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy	−$4.1M −225.0K shares	$1.7M 92.8K shares
MORGAN STANLEY RIA/Wealth	−$3.7M −203.6K shares	$26.0M 1.4M shares
J JANE STREET GROUP, LLC Institution	−$3.5M −193.8K shares	$4.5M 249.3K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited INVA in Q3 2025

New Positions: 18
New Value: $7.4M
Exited Positions: 37
Exited Value: $21.2M

New Positions

Institution	Position Value
Synergy Financial Management, LLC RIA/Wealth	$1.9M 101.5K shares
Janney Montgomery Scott LLC RIA/Wealth	$1.8M 100.0K shares
Morningstar Investment Management LLC Long Only Manager	$782.0K 42.9K shares
SIERRA SUMMIT ADVISORS LLC RIA/Wealth	$773.7K 42.4K shares
Y Y-Intercept Ltd Institution	$607.4K 33.3K shares
Cetera Investment Advisers RIA/Wealth	$480.7K 26.3K shares
NGAM ADVISORS, L.P. Long Only Manager	$303.3K 16.6K shares
D denkapparat Operations GmbH Institution	$284.8K 15.6K shares
V Vise Technologies, Inc. Institution	$229.6K 12.6K shares
HOHIMER WEALTH MANAGEMENT, LLC RIA/Wealth	$216.3K 11.9K shares

Exited Positions

Institution	Previous Position
Allspring Global Investments Holdings, LLC Long Only Manager	$5.9M 292.2K shares
C Cubist Systematic Strategies, LLC Institution	$3.5M 172.2K shares
C CANADA PENSION PLAN INVESTMENT BOARD Institution	$2.0M 98.2K shares
Aquatic Capital Management LLC Hedge Fund•Quant	$1.2M 60.8K shares
OCCUDO QUANTITATIVE STRATEGIES LP Hedge Fund•Market Neutral	$1.1M 56.7K shares
T TEXAS PERMANENT SCHOOL FUND Institution	$864.5K 43.0K shares
E Entropy Technologies, LP Hedge Fund•Quant Macro	$786.5K 39.1K shares
Edgestream Partners, L.P. Hedge Fund•Quant Macro	$762.6K 38.0K shares
A AXA Institution	$715.6K 35.6K shares
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy	$683.3K 34.0K shares

Options Activity

Institutions with the largest Call and Put options positions in INVA as of Q3 2025

Call Positions: 1
Call Value: $240.9K
Put Positions: 3
Put Value: $2.8M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$240.9K 132.0 contracts

Put Positions

Institution	Position Value
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.8M 981.0 contracts
J JANE STREET GROUP, LLC Institution	$744.6K 408.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$312.1K 171.0 contracts

Most Committed Institutions

Institutions with INVA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Sarissa Capital Management LP Hedge Fund•Activist	Alexander John Denner CEO	28.49% $51.4M	4.47% 2.8M shares	Q3 2016 Held for 9y 2m	$180.4M
Q QSV Equity Investors LLC Institution	-	1.48% $1.4M	0.13% 79.1K shares	Q4 2023 Held for 1y 11m	$97.9M
SYSTEMATIC FINANCIAL MANAGEMENT LP Long Only Manager	Kenneth Burgess CIO	0.94% $38.6M	3.36% 2.1M shares	Q2 2021 Held for 4y 5m	$4.1B
CHASE INVESTMENT COUNSEL CORP RIA/Wealth	Jennifer Leigh King CEO	0.40% $1.3M	0.11% 70.0K shares	Q4 2023 Held for 1y 11m	$322.7M
Uniplan Investment Counsel, Inc. RIA/Wealth	Kris Hunter Jamison CEO	0.36% $3.5M	0.30% 191.5K shares	Q3 2023 Held for 2y 2m	$983.7M
Virtus ETF Advisers LLC Long Only Manager	Richard William Smirl President	0.33% $491.8K	0.04% 26.9K shares	Q1 2025 Held for 8 months	$148.9M
Weiss Asset Management LP Hedge Fund•Multi-Strategy	Andrew Murray Weiss CEO	0.27% $14.0M	1.22% 768.9K shares	Q2 2025 Held for 5 months	$5.2B
D denkapparat Operations GmbH Institution	-	0.18% $284.8K	0.02% 15.6K shares	Q3 2025 Held for 2 months	$157.1M
H HUSSMAN STRATEGIC ADVISORS, INC. Institution	John Peter Hussman President	0.17% $766.5K	0.07% 42.0K shares	Q4 2020 Held for 4y 11m	$458.6M
DENALI ADVISORS LLC Long Only Manager	Robert Guenther Snigaroff CIO	0.16% $1.4M	0.12% 77.2K shares	Q2 2020 Held for 5y 5m	$885.1M

Hedge Fund Spotlight

Discover hedge funds investing in INVA

JACOBS LEVY EQUITY MANAGEMENT, INC

Hedge Fund • Quant

Portfolio ManagerBruce Ira Jacobs

Portfolio Value: $25.2B
Positions: 953
Last Reported: Q3 2025

Sector Allocation

Position in Innoviva, Inc.

Market Value: $1.5M
Shares Held: 81.7K
Portfolio Weight: 0.01%
Owned Since: 2025-Q1

Top Holding	Sector	Market Value	Weight
1 Nvidia NVDA	Semiconductors Technology	$1.7B	6.62%
2 Apple AAPL	Consumer Electronics Technology	$1.3B	5.29%
3 Microsoft MSFT	Software - Infrastructure Technology	$1.0B	4.05%