Vaxcyte, Inc.
PCVX • NASDAQ
Vaxcyte, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Carlos V. Paya, with a market cap of $5.8B. As of Q3 2025, 109% of shares are held by 274 institutional investors, with HENDERSON GROUP PLC as the largest holder at 10.09%.
Class I DirectorCarlos V. Paya
Market Cap$5.8B
Biotechnology
Healthcare
Employees254.0
Websitevaxcyte.com
Country
United States of America
Overview
Overview of institutional ownership in PCVX as of Q3 2025 with a market cap of $4.7B
All Institutions
- Institutions
- 274
- Value Held
- $5.1B
- Shares Held
- 141.2M
- Avg Position
- $18.6M
- Median Position
- $1.2M
Hedge Funds
- Hedge Funds
- 52
- Value Held
- $1.2B
- Shares Held
- 32.6M
- Avg Position
- $22.6M
- Median Position
- $4.2M
Ownership Breakdown
Based on market cap of $4.7B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in PCVX as of Q3 2025
| Institution | Position Value |
|---|---|
 HENDERSON GROUP PLC Institution | $472.0M 0.22% of portfolio |
 FMR LLC Institution | $450.6M 0.02% of portfolio |
 VANGUARD GROUP INC Institution | $443.8M 0.01% of portfolio |
 RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | $431.0M 5.35% of portfolio |
B BlackRock, Inc. Institution | $358.6M 0.01% of portfolio |
T T. Rowe Price Investment Management, Inc. Insurance Manager | $299.5M 0.19% of portfolio |
 WELLINGTON MANAGEMENT CO LLP Long Only Manager | $181.3M 0.03% of portfolio |
 STATE STREET CORP Institution | $172.4M 0.01% of portfolio |
D D. E. Shaw & Co., Inc. Institution | $154.6M 0.13% of portfolio |
 Paradigm Biocapital Advisors LP Hedge Fund•Long/Short | $136.3M 4.03% of portfolio |
Net Capital Flow
Institutional buying and selling activity for PCVX in Q3 2025
- Traded
- −$179.6M
- Buyers
- 133
- Sellers
- 142
- Total Bought
- +$429.7M
- Total Sold
- −$609.3M
- Avg Position
- $16.0M
Biggest Buyers
| Institution | Net Bought |
|---|---|
T T. Rowe Price Investment Management, Inc. Insurance Manager | +$83.4M +2.3M shares |
D D. E. Shaw & Co., Inc. Institution | +$43.3M +1.2M shares |
 Deep Track Capital, LP Hedge Fund•Long/Short | +$30.6M +850.0K shares |
 Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | +$25.1M +696.8K shares |
 WESTFIELD CAPITAL MANAGEMENT CO LP Long Only Manager | +$23.9M +663.8K shares |
 Logos Global Management LP Hedge Fund•Long/Short | +$22.5M +625.0K shares |
Paradigm Biocapital Advisors LP Hedge Fund•Long/Short | +$14.8M +411.9K shares |
 JPMORGAN CHASE & CO Institution | +$13.2M +366.3K shares |
FMR LLC Institution | +$12.9M +358.9K shares |
A ADAGE CAPITAL PARTNERS GP LLC Institution | +$12.0M +333.0K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 Capital Research Global Investors RIA/Wealth | −$141.5M −3.9M shares |
HENDERSON GROUP PLC Institution | −$57.2M −1.6M shares |
 PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager | −$53.4M −1.5M shares |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | −$31.9M −884.9K shares |
B BlackRock, Inc. Institution | −$24.7M −686.3K shares |
 FRANKLIN RESOURCES INC Institution | −$21.7M −603.2K shares |
 Clearbridge Investments, LLC Long Only Manager | −$21.0M −646.1K shares |
 UBS Group AG Institution | −$19.2M −533.3K shares |
E EVENTIDE ASSET MANAGEMENT, LLC Long Only Manager | −$16.9M −468.8K shares |
 BANK OF AMERICA CORP /DE/ Institution | −$16.1M −447.6K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited PCVX in Q3 2025
- New Positions
- 12
- New Value
- $5.7M
- Exited Positions
- 42
- Exited Value
- $65.5M
New Positions
| Institution | Position Value |
|---|---|
 Voleon Capital Management LP Hedge Fund•Quant | $2.8M 78.9K shares |
 Weiss Asset Management LP Hedge Fund•Multi-Strategy | $1.4M 39.2K shares |
 Bridgewater Associates, LP Hedge Fund•Global Macro | $427.0K 11.9K shares |
P Point72 Asia Pte. Ltd. Institution | $339.8K 9.4K shares |
Q Quantessence Capital LLC Hedge Fund•Quant | $282.6K 7.8K shares |
 Meeder Advisory Services, Inc. Long Only Manager | $209.6K 5.8K shares |
 Point72 Ltd RIA/Wealth | $141.6K 3.9K shares |
 FINANCIAL CONSULATE, INC RIA/Wealth | $9.0K 250.0 shares |
 Johnson Financial Group, Inc. RIA/Wealth | $1.2K 33.0 shares |
 JPL Wealth Management, LLC RIA/Wealth | $181.0 5.0 shares |
Exited Positions
| Institution | Previous Position |
|---|---|
Clearbridge Investments, LLC Long Only Manager | $21.0M 646.1K shares |
 Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy | $11.8M 362.6K shares |
S Siren, L.L.C. Institution | $9.6M 295.5K shares |
 DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short | $7.3M 225.0K shares |
 Candriam Luxembourg S.C.A. Long Only Manager | $2.4M 74.7K shares |
 DRIEHAUS CAPITAL MANAGEMENT LLC Hedge Fund•Event Driven | $2.4M 73.4K shares |
 WCM INVESTMENT MANAGEMENT/CA Long Only Manager | $2.3M 70.4K shares |
X XTX Topco Ltd Institution | $1.4M 41.7K shares |
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy | $1.2M 35.8K shares |
 BANK OF MONTREAL /CAN/ Institution | $1.0M 31.5K shares |
Options Activity
Institutions with the largest Call and Put options positions in PCVX as of Q3 2025
- Call Positions
- 10
- Call Value
- $14.9M
- Put Positions
- 6
- Put Value
- $4.2M
Call Positions
| Institution | Position Value |
|---|---|
N NOMURA HOLDINGS INC Institution | $5.3M 1.5K contracts |
J JANE STREET GROUP, LLC Institution | $2.7M 762.0 contracts |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $2.1M 587.0 contracts |
 Caption Management, LLC Hedge Fund•Long/Short | $1.8M 500.0 contracts |
S SIG BROKERAGE, LP Institution | $1.1M 315.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $1.1M 304.0 contracts |
 TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy | $378.2K 105.0 contracts |
 Ikarian Capital, LLC Hedge Fund•Event Driven | $252.1K 70.0 contracts |
 CITIGROUP INC Institution | - - contracts |
 GOLDMAN SACHS GROUP INC Institution | - - contracts |
Put Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $3.1M 872.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $594.3K 165.0 contracts |
J JANE STREET GROUP, LLC Institution | $443.0K 123.0 contracts |
CITIGROUP INC Institution | - - contracts |
 BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | - - contracts |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | - - contracts |
Most Committed Institutions
Institutions with PCVX as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
28.58% $49.4M | |
K Kynam Capital Management, LP Hedge Fund•Long/Short | 8.24% $110.6M |
S Saturn V Capital Management LLC Hedge Fund•Sector | 6.23% $28.4M |
 DIADEMA PARTNERS LP Hedge Fund•Long/Short | 5.49% $7.9M |
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | 5.35% $431.0M |
Paradigm Biocapital Advisors LP Hedge Fund•Long/Short | 4.03% $136.3M |
 Eversept Partners, LLC Hedge Fund•Long/Short | 3.92% $51.2M |
Deep Track Capital, LP Hedge Fund•Long/Short | 3.07% $108.1M |
Logos Global Management LP Hedge Fund•Long/Short | 2.28% $22.5M |
Ikarian Capital, LLC Hedge Fund•Event Driven | 2.27% $11.2M |
Hedge Fund Spotlight
Discover hedge funds investing in PCVX
E
Entropy Technologies, LP
Hedge Fund • Quant Macro
Portfolio ManagerArjun Rajan Modi
- Portfolio Value
- $1.3B
- Positions
- 787
- Last Reported
- Q3 2025
Sector Allocation
Position in Vaxcyte, Inc.
- Market Value
- $563.3K
- Shares Held
- 15.6K
- Portfolio Weight
- 0.04%
- Owned Since
- 2025-Q2
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Semiconductors Technology | $13.2M | 0.98% | |
Oil & Gas Integrated Energy | $13.0M | 0.97% | |
Financial - Credit Services Financial Services | $13.0M | 0.97% |
