C4 Therapeutics

CCCC • NASDAQ

C4 Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by Kendra Adams, with a market cap of $239.4M. As of Q3 2025, 74% of shares are held by 96 institutional investors, with Lynx1 Capital Management LP as the largest holder at 9.97%.

Chief Financial OfficerKendra Adams

Market Cap$239.4M

Biotechnology

Healthcare

Employees145.0

Websitec4therapeutics.com

Country

United States of America

Overview

Overview of institutional ownership in CCCC as of Q3 2025 with a market cap of $158.0M

All Institutions

Institutions: 96
Value Held: $116.6M
Shares Held: 52.5M
Avg Position: $1.2M
Median Position: $142.3K

Hedge Funds

Hedge Funds: 18
Value Held: $60.5M
Shares Held: 27.2M
Avg Position: $3.4M
Median Position: $1.1M

Ownership Breakdown

Institutional (non-HF)

35.55%

$56.2M

Hedge Funds

38.27%

$60.5M

Retail & Other

26.18%

$41.4M

Based on market cap of $158.0M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in CCCC as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
L Lynx1 Capital Management LP Hedge Fund•Sector	Weston Agnew Nichols CIO	$15.8M 3.21% of portfolio	9.97% 7.1M shares	Q3 2023 Held for 2y 2m	$491.3M
Soleus Capital Management, L.P. Hedge Fund•Long/Short	Guy Bezalel Levy CIO	$15.7M 0.86% of portfolio	9.91% 7.1M shares	Q4 2020 Held for 4y 11m	$1.8B
ORBIMED ADVISORS LLC Hedge Fund•Sector	Sam Block Iii CFO	$11.6M 0.28% of portfolio	7.36% 5.2M shares	Q2 2024 Held for 1y 5m	$4.1B
MORGAN STANLEY RIA/Wealth	Jed Finn CEO	$11.0M 0.00% of portfolio	6.99% 5.0M shares	Q4 2020 Held for 4y 11m	$1.65T
WASATCH ADVISORS INC Long Only Manager	Michael Kenneth Yeates CEO	$10.8M 0.06% of portfolio	6.82% 4.9M shares	Q1 2021 Held for 4y 8m	$18.6B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$7.1M 0.00% of portfolio	4.48% 3.2M shares	Q4 2020 Held for 4y 11m	$6.69T
BANK OF AMERICA CORP /DE/ Institution	Brian T. Moynihan CEO	$4.6M 0.00% of portfolio	2.88% 2.1M shares	Q4 2020 Held for 4y 11m	$1.33T
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$4.3M 0.00% of portfolio	2.72% 1.9M shares	Q1 2023 Held for 2y 8m	$121.98B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	$4.2M 0.61% of portfolio	2.67% 1.9M shares	Q1 2024 Held for 1y 8m	$689.7M
B BlackRock, Inc. Institution	-	$3.5M 0.00% of portfolio	2.24% 1.6M shares	Q4 2020 Held for 4y 11m	$5.67T

Net Capital Flow

Institutional buying and selling activity for CCCC in Q3 2025

Traded: −$3.4M
Buyers: 49
Sellers: 61
Total Bought: +$12.8M
Total Sold: −$16.2M
Avg Position: $948.3K

Biggest Buyers

Institution	Net Bought	Current Position
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	+$4.2M +1.9M shares	$4.2M 1.9M shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$1.8M +832.9K shares	$4.3M 1.9M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$1.1M +481.4K shares	$1.1M 481.4K shares
S Shay Capital LLC Institution	+$932.4K +420.0K shares	$932.4K 420.0K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	+$831.1K +374.4K shares	$1.1M 515.4K shares
MORGAN STANLEY RIA/Wealth	+$483.6K +217.8K shares	$11.0M 5.0M shares
VANGUARD GROUP INC Institution	+$385.2K +173.5K shares	$7.1M 3.2M shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$335.5K +151.1K shares	$1.9M 834.7K shares
Susquehanna Portfolio Strategies, LLC Private Equity	+$322.2K +145.2K shares	$604.0K 272.1K shares
Q Qube Research & Technologies Ltd Institution	+$257.5K +116.0K shares	$257.5K 116.0K shares

Biggest Sellers

Institution	Net Sold	Current Position
WASATCH ADVISORS INC Long Only Manager	−$5.7M −2.6M shares	$10.8M 4.9M shares
ORBIMED ADVISORS LLC Hedge Fund•Sector	−$3.5M −1.6M shares	$11.6M 5.2M shares
UBS Group AG Institution	−$1.1M −510.4K shares	$136.9K 61.7K shares
GOLDMAN SACHS GROUP INC Institution	−$933.2K −420.4K shares	$1.0M 459.9K shares
J JANE STREET GROUP, LLC Institution	−$641.7K −289.0K shares	$451.9K 203.6K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$548.8K −383.8K shares	Sold Off 0 shares
B BlackRock, Inc. Institution	−$517.2K −233.0K shares	$3.5M 1.6M shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	−$346.8K −156.2K shares	$2.1M 937.0K shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	−$286.0K −200.0K shares	Sold Off 0 shares
B BNP PARIBAS ARBITRAGE, SA Institution	−$278.3K −125.4K shares	$179.4K 80.8K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited CCCC in Q3 2025

New Positions: 9
New Value: $230.6K
Exited Positions: 26
Exited Value: $1.9M

New Positions

Institution	Position Value
LEUCADIA NATIONAL CORP Institution	$84.8K 38.2K shares
Voleon Capital Management LP Hedge Fund•Quant	$63.1K 28.4K shares
ZACKS INVESTMENT MANAGEMENT RIA/Wealth	$29.0K 13.0K shares
W WOLVERINE TRADING, LLC Institution	$28.3K 12.7K shares
Simplicity Wealth,LLC RIA/Wealth	$22.7K 10.2K shares
JFS WEALTH ADVISORS, LLC RIA/Wealth	$2.2K 1.0K shares
Sontag Advisory, LLC RIA/Wealth	$222.0 100.0 shares
A Advisory Services Network, LLC RIA/Wealth	$164.0 74.0 shares
SRS Capital Advisors, Inc. RIA/Wealth	$122.0 55.0 shares

Exited Positions

Institution	Previous Position
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	$548.8K 383.8K shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	$286.0K 200.0K shares
Atom Investors LP Hedge Fund•Market Neutral	$272.0K 190.2K shares
Jain Global LLC Hedge Fund•Multi-Strategy	$194.8K 136.2K shares
Aster Capital Management Ltd RIA/Wealth	$111.2K 77.7K shares
H HRT FINANCIAL LLC Institution	$101.7K 71.1K shares
Y Y-Intercept Ltd Institution	$75.1K 52.5K shares
Brookstone Capital Management RIA/Wealth	$41.9K 29.3K shares
Savant Capital, LLC RIA/Wealth	$37.7K 26.3K shares
V Virtu Financial LLC Institution	$34.9K 24.4K shares

Options Activity

Institutions with the largest Call and Put options positions in CCCC as of Q3 2025

Call Positions: 5
Call Value: $731.2K
Put Positions: 2
Put Value: $412.5K

Call Positions

Institution	Position Value
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$312.4K 1.4K contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	$199.8K 900.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$135.6K 611.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$54.4K 245.0 contracts
W WOLVERINE TRADING, LLC Institution	$29.0K 130.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$291.7K 1.3K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$120.8K 544.0 contracts

Most Committed Institutions

Institutions with CCCC as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
L Lynx1 Capital Management LP Hedge Fund•Sector	Weston Agnew Nichols CIO	3.21% $15.8M	9.97% 7.1M shares	Q3 2023 Held for 2y 2m	$491.3M
Soleus Capital Management, L.P. Hedge Fund•Long/Short	Guy Bezalel Levy CIO	0.86% $15.7M	9.91% 7.1M shares	Q4 2020 Held for 4y 11m	$1.8B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	0.61% $4.2M	2.67% 1.9M shares	Q1 2024 Held for 1y 8m	$689.7M
ORBIMED ADVISORS LLC Hedge Fund•Sector	Sam Block Iii CFO	0.28% $11.6M	7.36% 5.2M shares	Q2 2024 Held for 1y 5m	$4.1B
S Shay Capital LLC Institution	-	0.17% $932.4K	0.59% 420.0K shares	Q1 2025 Held for 8 months	$548.9M
B Bain Capital Life Sciences Investors, LLC Institution	-	0.16% $2.5M	1.56% 1.1M shares	Q4 2020 Held for 4y 11m	$1.5B
I INTREPID FAMILY OFFICE LLC Institution	-	0.15% $155.4K	0.10% 70.0K shares	Q4 2024 Held for 11 months	$102.3M
V Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group Institution	-	0.11% $188.7K	0.12% 85.0K shares	Q4 2021 Held for 3y 11m	$169.3M
T TANG CAPITAL MANAGEMENT LLC Institution	-	0.08% $2.0M	1.26% 900.0K shares	Q2 2024 Held for 1y 5m	$2.5B
WASATCH ADVISORS INC Long Only Manager	Michael Kenneth Yeates CEO	0.06% $10.8M	6.82% 4.9M shares	Q1 2021 Held for 4y 8m	$18.6B

Hedge Fund Spotlight

Discover hedge funds investing in CCCC

TWO SIGMA INVESTMENTS LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerScott David Hoffman

Portfolio Value: $62.0B
Positions: 3,252
Last Reported: Q3 2025

Sector Allocation

Position in C4 Therapeutics

Market Value: $1.9M
Shares Held: 834.7K
Portfolio Weight: 0.00%
Owned Since: 2021-Q2

Top Holding	Sector	Market Value	Weight
1 SPDR S&P 500 ETF Trust SPY	ETF ETF	$680.4M	1.10%
2 Financial Select Sector SPDR Fund XLF	ETF ETF	$582.6M	0.94%
3 Consumer Staples Select Sector SPDR Fund XLP	ETF ETF	$489.6M	0.79%