Contineum Therapeutics, Inc.

CTNM • NASDAQ

Contineum Therapeutics, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Carmine Stengone, with a market cap of $339.4M. As of Q3 2025, 62% of shares are held by 61 institutional investors, with RA CAPITAL MANAGEMENT, LLC as the largest holder at 7.57%.

Chief Executive Officer and PresidentCarmine Stengone

Market Cap$339.4M

Biotechnology

Healthcare

Websitecontineum-tx.com

Country

United States of America

Overview

Overview of institutional ownership in CTNM as of Q3 2025 with a market cap of $329.5M

All Institutions

Institutions: 61
Value Held: $205.4M
Shares Held: 17.5M
Avg Position: $3.4M
Median Position: $488.6K

Hedge Funds

Hedge Funds: 16
Value Held: $85.4M
Shares Held: 7.3M
Avg Position: $5.3M
Median Position: $1.7M

Ownership Breakdown

Institutional (non-HF)

36.42%

$120.0M

Hedge Funds

25.91%

$85.4M

Retail & Other

37.67%

$124.1M

Based on market cap of $329.5M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in CTNM as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	$24.9M 0.31% of portfolio	7.57% 2.1M shares	Q3 2025 Held for 2 months	$8.1B
JOHNSON & JOHNSON Institution	Joaquin Duato CEO	$23.3M 4.62% of portfolio	7.06% 2.0M shares	Q2 2024 Held for 1y 5m	$503.7M
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	$20.2M 0.61% of portfolio	6.13% 1.7M shares	Q2 2024 Held for 1y 5m	$3.3B
FRANKLIN RESOURCES INC Institution	Gregory E. Johnson CEO	$19.5M 0.00% of portfolio	5.90% 1.7M shares	Q2 2024 Held for 1y 5m	$395.36B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$11.3M 0.00% of portfolio	3.44% 964.2K shares	Q2 2024 Held for 1y 5m	$6.69T
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dmitry Balyasny CIO	$11.2M 0.02% of portfolio	3.39% 951.3K shares	Q3 2025 Held for 2 months	$48.1B
FMR LLC Institution	-	$9.6M 0.00% of portfolio	2.91% 814.9K shares	Q2 2024 Held for 1y 5m	$1.92T
SECTORAL ASSET MANAGEMENT INC Venture Capital	Jerome Georges Pfund CEO	$9.4M 5.90% of portfolio	2.86% 800.8K shares	Q2 2024 Held for 1y 5m	$159.6M
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short	Joseph Eric Edelman CEO	$8.4M 0.24% of portfolio	2.55% 714.6K shares	Q2 2024 Held for 1y 5m	$3.5B
H Hillhouse Capital Advisors, Ltd. Institution	-	$7.9M 0.21% of portfolio	2.39% 669.3K shares	Q2 2024 Held for 1y 5m	$3.7B

Net Capital Flow

Institutional buying and selling activity for CTNM in Q3 2025

Traded: +$49.4M
Buyers: 33
Sellers: 38
Total Bought: +$60.2M
Total Sold: −$10.9M
Avg Position: $2.5M

Biggest Buyers

Institution	Net Bought	Current Position
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	+$24.9M +2.1M shares	$24.9M 2.1M shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$11.2M +951.3K shares	$11.2M 951.3K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$6.0M +513.6K shares	$7.6M 646.0K shares
VANGUARD GROUP INC Institution	+$2.6M +220.2K shares	$11.3M 964.2K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	+$2.2M +184.0K shares	$2.4M 204.1K shares
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	+$2.0M +166.2K shares	$2.0M 166.2K shares
Marshall Wace LLP Institution	+$1.9M +164.8K shares	$2.3M 193.5K shares
B BlackRock, Inc. Institution	+$1.8M +156.6K shares	$3.8M 322.0K shares
GEODE CAPITAL MANAGEMENT LLC ETF Provider	+$1.6M +139.7K shares	$2.5M 211.1K shares
Eversept Partners, LLC Hedge Fund•Long/Short	+$1.6M +134.6K shares	$1.6M 134.6K shares

Biggest Sellers

Institution	Net Sold	Current Position
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	−$2.8M −234.8K shares	$912.6K 77.7K shares
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy	−$1.7M −145.6K shares	$217.3K 18.5K shares
S Saturn V Capital Management LLC Hedge Fund•Sector	−$1.3M −319.3K shares	Sold Off 0 shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	−$1.0M −88.8K shares	$916.0K 78.0K shares
S Squarepoint Ops LLC Hedge Fund•Quant	−$896.9K −76.3K shares	$153.8K 13.1K shares
FRANKLIN RESOURCES INC Institution	−$508.5K −43.3K shares	$19.5M 1.7M shares
GOLDMAN SACHS GROUP INC Institution	−$361.7K −30.8K shares	$354.1K 30.1K shares
FMR LLC Institution	−$332.3K −28.3K shares	$9.6M 814.9K shares
Monaco Asset Management SAM RIA/Wealth	−$297.8K −75.0K shares	Sold Off 0 shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	−$270.5K −23.0K shares	$445.8K 37.9K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited CTNM in Q3 2025

New Positions: 14
New Value: $40.5M
Exited Positions: 21
Exited Value: $2.4M

New Positions

Institution	Position Value
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$24.9M 2.1M shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$11.2M 951.3K shares
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$2.0M 166.2K shares
Eversept Partners, LLC Hedge Fund•Long/Short	$1.6M 134.6K shares
Trexquant Investment LP Hedge Fund•Quant	$344.4K 29.3K shares
Baker Ellis Asset Management LLC RIA/Wealth	$229.1K 19.5K shares
BAILARD, INC. RIA/Wealth	$145.1K 12.4K shares
Mariner Wealth Advisors, LLC RIA/Wealth	$122.4K 10.4K shares
S SIMPLEX TRADING, LLC Institution	$10.5K 895.0 shares
G GROUP ONE TRADING, L.P. Institution	$5.9K 500.0 shares

Exited Positions

Institution	Previous Position
S Saturn V Capital Management LLC Hedge Fund•Sector	$1.3M 319.3K shares
Monaco Asset Management SAM RIA/Wealth	$297.8K 75.0K shares
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy	$171.5K 43.2K shares
Y Y-Intercept Ltd Institution	$139.6K 35.2K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	$99.9K 25.2K shares
J JANE STREET GROUP, LLC Institution	$80.7K 20.3K shares
Jain Global LLC Hedge Fund•Multi-Strategy	$77.8K 19.6K shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	$68.5K 17.2K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$65.5K 16.5K shares
SPRINGBOK CAPITAL MANAGEMENT, LLC Fund of Funds	$55.3K 13.9K shares

Options Activity

Institutions with the largest Call and Put options positions in CTNM as of Q3 2025

Call Positions: 1
Call Value: $225.6K
Put Positions: 0
Put Value: -

Call Positions

Institution	Position Value
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	$225.6K 192.0 contracts

Put Positions

Institution	Position Value
No put positions found

Most Committed Institutions

Institutions with CTNM as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
R Red Tree Management, LLC Institution	-	9.04% $7.5M	2.28% 638.2K shares	Q4 2024 Held for 11 months	$82.9M
SECTORAL ASSET MANAGEMENT INC Venture Capital	Jerome Georges Pfund CEO	5.90% $9.4M	2.86% 800.8K shares	Q2 2024 Held for 1y 5m	$159.6M
JOHNSON & JOHNSON Institution	Joaquin Duato CEO	4.62% $23.3M	7.06% 2.0M shares	Q2 2024 Held for 1y 5m	$503.7M
V Versant Venture Management, LLC Institution	-	3.00% $6.4M	1.94% 542.6K shares	Q2 2024 Held for 1y 5m	$212.5M
Samsara BioCapital, LLC Venture Capital	Miran Nasruddin Ahmad CFO	0.88% $6.7M	2.04% 571.1K shares	Q2 2024 Held for 1y 5m	$765.9M
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	0.61% $20.2M	6.13% 1.7M shares	Q2 2024 Held for 1y 5m	$3.3B
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	0.31% $24.9M	7.57% 2.1M shares	Q3 2025 Held for 2 months	$8.1B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	0.28% $2.0M	0.59% 166.2K shares	Q3 2025 Held for 2 months	$689.7M
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short	Joseph Eric Edelman CEO	0.24% $8.4M	2.55% 714.6K shares	Q2 2024 Held for 1y 5m	$3.5B
H Hillhouse Capital Advisors, Ltd. Institution	-	0.21% $7.9M	2.39% 669.3K shares	Q2 2024 Held for 1y 5m	$3.7B

Hedge Fund Spotlight

Discover hedge funds investing in CTNM

BAKER BROS. ADVISORS LP

Hedge Fund • Sector

Portfolio ManagerScott Lawrence Lessing

Portfolio Value: $10.8B
Positions: 88
Last Reported: Q3 2025

Sector Allocation

Position in Contineum Therapeutics, Inc.

Market Value: $912.6K
Shares Held: 77.7K
Portfolio Weight: 0.01%
Owned Since: 2024-Q2

Top Holding	Sector	Market Value	Weight
1 Incyte INCY	Biotechnology Healthcare	$2.6B	24.14%
2 Madrigal Pharmaceuticals, Inc. MDGL	Biotechnology Healthcare	$982.3M	9.10%
3 Insmed INSM	Biotechnology Healthcare	$965.4M	8.94%