Scholar Rock

SRRK • NASDAQ

Scholar Rock is a biotechnology company in the healthcare sector on NASDAQ, led by Jay Backstrom, with a market cap of $4.6B. As of Q3 2025, 121% of shares are held by 235 institutional investors, with FMR LLC as the largest holder at 14.58%.

President & Chief Executive OfficerJay Backstrom

Market Cap$4.6B

Biotechnology

Healthcare

Employees150.0

Websitescholarrock.com

Country

United States of America

Overview

Overview of institutional ownership in SRRK as of Q3 2025 with a market cap of $3.6B

All Institutions

Institutions: 235
Value Held: $4.3B
Shares Held: 115.8M
Avg Position: $18.4M
Median Position: $907.5K

Hedge Funds

Hedge Funds: 32
Value Held: $766.5M
Shares Held: 20.6M
Avg Position: $24.0M
Median Position: $5.8M

Ownership Breakdown

Institutional (non-HF)

99.09%

$3.5B

Hedge Funds

21.41%

$766.5M

Retail & Other

Based on market cap of $3.6B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in SRRK as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
FMR LLC Institution	-	$521.8M 0.03% of portfolio	14.58% 14.0M shares	Q2 2018 Held for 7y 5m	$1.92T
S Siren, L.L.C. Institution	-	$344.5M 14.44% of portfolio	9.62% 9.3M shares	Q3 2024 Held for 1y 2m	$2.4B
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	Robert W Sharps President	$256.3M 0.03% of portfolio	7.16% 6.9M shares	Q2 2018 Held for 7y 5m	$912.31B
B BlackRock, Inc. Institution	-	$251.7M 0.00% of portfolio	7.03% 6.8M shares	Q3 2018 Held for 7y 2m	$5.67T
Samsara BioCapital, LLC Venture Capital	Miran Nasruddin Ahmad CFO	$209.0M 27.29% of portfolio	5.84% 5.6M shares	Q1 2022 Held for 3y 8m	$765.9M
VANGUARD GROUP INC Institution	Salim Ramji CEO	$183.0M 0.00% of portfolio	5.11% 4.9M shares	Q2 2018 Held for 7y 5m	$6.69T
WELLINGTON MANAGEMENT CO LLP Long Only Manager	Edmund Wellington Iii President	$169.3M 0.03% of portfolio	4.73% 4.5M shares	Q4 2023 Held for 1y 11m	$571.21B
R Redmile Group, LLC Hedge Fund•Sector	Jeremy Charles Green Managing Partner	$145.4M 14.15% of portfolio	4.06% 3.9M shares	Q2 2018 Held for 7y 5m	$1.0B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$140.1M 0.00% of portfolio	3.91% 3.8M shares	Q3 2018 Held for 7y 2m	$2.88T
B Bellevue Group AG Institution	-	$120.8M 2.52% of portfolio	3.38% 3.2M shares	Q2 2019 Held for 6y 5m	$4.8B

Net Capital Flow

Institutional buying and selling activity for SRRK in Q3 2025

Net Flow: +$139.1M
Buyers: 99
Sellers: 96
Total Bought: +$487.4M
Total Sold: −$348.3M
Avg Position: $17.9M

Biggest Buyers

Institution	Net Bought	Current Position
WELLINGTON MANAGEMENT CO LLP Long Only Manager	+$93.9M +2.5M shares	$169.3M 4.5M shares
JENNISON ASSOCIATES LLC Long Only Manager	+$46.2M +1.2M shares	$59.8M 1.6M shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$32.6M +874.4K shares	$37.5M 1.0M shares
DRIEHAUS CAPITAL MANAGEMENT LLC Hedge Fund•Event Driven	+$31.5M +846.4K shares	$75.4M 2.0M shares
UBS Group AG Institution	+$29.5M +792.8K shares	$42.1M 1.1M shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	+$27.4M +736.9K shares	$72.7M 2.0M shares
STATE STREET CORP Institution	+$25.7M +688.8K shares	$140.1M 3.8M shares
HENDERSON GROUP PLC Institution	+$21.0M +563.2K shares	$112.2M 3.0M shares
FEDERATED INVESTORS INC /PA/ Long Only Manager	+$20.8M +559.5K shares	$29.8M 800.5K shares
JPMORGAN CHASE & CO Institution	+$16.4M +440.4K shares	$26.6M 714.0K shares

Biggest Sellers

Institution	Net Sold	Current Position
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	−$70.0M −1.9M shares	$256.3M 6.9M shares
COMMODORE CAPITAL LP Hedge Fund•Long/Short	−$51.4M −1.5M shares	Sold Off 0 shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$31.4M −842.0K shares	$5.0M 134.6K shares
Polar Capital Holdings Plc Long Only Manager	−$26.3M −705.9K shares	$29.6M 794.1K shares
Marshall Wace LLP Institution	−$24.8M −666.5K shares	$36.3M 973.9K shares
M Man Group plc Institution	−$21.1M −567.0K shares	$1.3M 34.2K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$14.0M −374.7K shares	$20.8M 558.7K shares
LORD, ABBETT & CO. LLC Long Only Manager	−$12.2M −326.5K shares	$5.5M 147.7K shares
MORGAN STANLEY RIA/Wealth	−$11.2M −300.4K shares	$22.5M 604.0K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	−$10.3M −291.2K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited SRRK in Q3 2025

New Positions: 27
New Value: $122.5M
Exited Positions: 35
Exited Value: $99.7M

New Positions

Institution	Position Value
Holocene Advisors, LP Hedge Fund•Long/Short	$91.7M 2.5M shares
O Orbis Allan Gray Ltd RIA/Wealth	$11.3M 302.3K shares
P PEREGRINE CAPITAL MANAGEMENT LLC Long Only Manager	$5.8M 154.9K shares
A Aisling Capital Management LP Private Equity	$2.9M 77.0K shares
StoneCrest Wealth Management, Inc. RIA/Wealth	$1.8M 47.3K shares
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short	$1.5M 39.5K shares
NAN FUNG TRINITY Ltd RIA/Wealth	$1.4M 37.6K shares
Jain Global LLC Hedge Fund•Multi-Strategy	$1.4M 36.7K shares
L Longaeva Partners L.P. Institution	$982.6K 26.4K shares
VERUS CAPITAL PARTNERS, LLC RIA/Wealth	$699.0K 18.8K shares

Exited Positions

Institution	Previous Position
COMMODORE CAPITAL LP Hedge Fund•Long/Short	$51.4M 1.5M shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	$10.3M 291.2K shares
Patient Square Capital LP Private Equity	$5.5M 154.0K shares
Soleus Capital Management, L.P. Hedge Fund•Long/Short	$4.4M 125.0K shares
A AXA Institution	$3.3M 93.0K shares
Exome Asset Management LLC Hedge Fund•Sector	$3.0M 84.3K shares
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$2.2M 62.9K shares
EAM Investors, LLC Long Only Manager	$2.2M 62.3K shares
G GREAT POINT PARTNERS LLC Private Equity	$2.2M 61.6K shares
S SPHERA FUNDS MANAGEMENT LTD. Institution	$2.0M 57.5K shares

Options Activity

Institutions with the largest Call and Put options positions in SRRK as of Q3 2025

Call Positions: 14
Call Value: $74.4M
Put Positions: 16
Put Value: $83.4M

Call Positions

Institution	Position Value
Ikarian Capital, LLC Hedge Fund•Event Driven	$20.9M 5.6K contracts
J JANE STREET GROUP, LLC Institution	$12.1M 3.2K contracts
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$8.4M 2.3K contracts
Caption Management, LLC Hedge Fund•Long/Short	$7.7M 2.1K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$6.5M 1.7K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$5.5M 1.5K contracts
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$3.7M 1.0K contracts
ORBIMED ADVISORS LLC Hedge Fund•Sector	$3.7M 1.0K contracts
L LMR Partners LLP Institution	$3.6M 961.0 contracts
J J. Goldman & Co LP Hedge Fund•Multi-Strategy	$1.0M 270.0 contracts

Put Positions

Institution	Position Value
Hudson Bay Capital Management LP Hedge Fund•Multi-Strategy	$20.5M 5.5K contracts
J JANE STREET GROUP, LLC Institution	$19.6M 5.3K contracts
Caption Management, LLC Hedge Fund•Long/Short	$15.9M 4.3K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$8.6M 2.3K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$5.5M 1.5K contracts
LEUCADIA NATIONAL CORP Institution	$4.6M 1.2K contracts
Ikarian Capital, LLC Hedge Fund•Event Driven	$3.6M 962.0 contracts
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$1.3M 350.0 contracts
N NOMURA HOLDINGS INC Institution	$931.0K 250.0 contracts
L LMR Partners LLP Institution	$904.9K 243.0 contracts

Most Committed Institutions

Institutions with SRRK as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Samsara BioCapital, LLC Venture Capital	Miran Nasruddin Ahmad CFO	27.29% $209.0M	5.84% 5.6M shares	Q1 2022 Held for 3y 8m	$765.9M
S Siren, L.L.C. Institution	-	14.44% $344.5M	9.62% 9.3M shares	Q3 2024 Held for 1y 2m	$2.4B
R Redmile Group, LLC Hedge Fund•Sector	Jeremy Charles Green Managing Partner	14.15% $145.4M	4.06% 3.9M shares	Q2 2018 Held for 7y 5m	$1.0B
Fairmount Funds Management LLC Hedge Fund•Sector	Daniel Eric Greenberg Managing Partner	6.11% $67.9M	1.90% 1.8M shares	Q4 2024 Held for 11 months	$1.1B
StemPoint Capital LP Hedge Fund•Long/Short	Sean Chua Tan President	5.45% $27.0M	0.76% 726.2K shares	Q4 2024 Held for 11 months	$495.9M
E Eagle Health Investments LP Hedge Fund•Long/Short	Gary Johnathan Stern Founder	3.55% $13.5M	0.38% 363.3K shares	Q2 2025 Held for 5 months	$380.9M
Vestal Point Capital, LP Hedge Fund•Long/Short	Ryan Christopher Wilder CIO	2.83% $55.9M	1.56% 1.5M shares	Q1 2025 Held for 8 months	$2.0B
B Bellevue Group AG Institution	-	2.52% $120.8M	3.38% 3.2M shares	Q2 2019 Held for 6y 5m	$4.8B
Paradigm Biocapital Advisors LP Hedge Fund•Long/Short	Dr. Senai Nmn Asefaw CIO	2.21% $74.8M	2.09% 2.0M shares	Q4 2024 Held for 11 months	$3.4B
N Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. Institution	-	2.21% $28.7M	0.80% 769.4K shares	Q4 2024 Held for 11 months	$1.3B