Akebia Therapeutics

AKBA • NASDAQ

Akebia Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by John Butler, with a market cap of $440.5M. As of Q3 2025, 47% of shares are held by 175 institutional investors, with BlackRock, Inc. as the largest holder at 7.09%.

President and Chief Executive OfficerJohn Butler

Market Cap$440.5M

Biotechnology

Healthcare

Employees167.0

Websiteakebia.com

Country

United States of America

Overview

Overview of institutional ownership in AKBA as of Q3 2025 with a market cap of $723.8M

All Institutions

Institutions: 175
Value Held: $337.6M
Shares Held: 123.7M
Avg Position: $1.9M
Median Position: $161.1K

Hedge Funds

Hedge Funds: 23
Value Held: $50.3M
Shares Held: 18.4M
Avg Position: $2.2M
Median Position: $578.1K

Ownership Breakdown

Institutional (non-HF)

39.69%

$287.3M

Hedge Funds

6.95%

$50.3M

Retail & Other

53.36%

$386.2M

Based on market cap of $723.8M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in AKBA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$51.3M 0.00% of portfolio	7.09% 18.8M shares	Q2 2014 Held for 11y 5m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$42.4M 0.00% of portfolio	5.86% 15.5M shares	Q2 2014 Held for 11y 5m	$6.69T
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$32.3M 0.00% of portfolio	4.47% 11.8M shares	Q2 2014 Held for 11y 5m	$2.88T
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$16.9M 0.00% of portfolio	2.33% 6.2M shares	Q2 2014 Held for 11y 5m	$1.57T
MORGAN STANLEY RIA/Wealth	Jed Finn CEO	$11.8M 0.00% of portfolio	1.63% 4.3M shares	Q2 2014 Held for 11y 5m	$1.65T
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	$10.8M 0.01% of portfolio	1.49% 4.0M shares	Q3 2019 Held for 6y 2m	$75.8B
UBS Group AG Institution	Sergio P. Ermotti CEO	$10.0M 0.00% of portfolio	1.38% 3.6M shares	Q4 2014 Held for 10y 11m	$511.54B
Q Qube Research & Technologies Ltd Institution	-	$8.8M 0.01% of portfolio	1.21% 3.2M shares	Q2 2022 Held for 3y 5m	$70.6B
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	Kenneth Cordele Griffin CEO	$8.7M 0.01% of portfolio	1.20% 3.2M shares	Q2 2015 Held for 10y 5m	$122.08B
MPM Oncology Impact Management LP Institution	Christian Albrecht Wulf Von Schimmelmann Managing Partner	$7.9M 1.29% of portfolio	1.09% 2.9M shares	Q2 2025 Held for 5 months	$610.9M

Net Capital Flow

Institutional buying and selling activity for AKBA in Q3 2025

Traded: +$37.7M
Buyers: 104
Sellers: 57
Total Bought: +$75.4M
Total Sold: −$37.7M
Avg Position: $1.7M

Biggest Buyers

Institution	Net Bought	Current Position
STATE STREET CORP Institution	+$10.5M +3.8M shares	$32.3M 11.8M shares
UBS Group AG Institution	+$8.2M +3.0M shares	$10.0M 3.6M shares
Invesco Ltd. ETF Provider	+$5.5M +2.0M shares	$6.6M 2.4M shares
CITIGROUP INC Institution	+$4.9M +1.8M shares	$5.2M 1.9M shares
Q Qube Research & Technologies Ltd Institution	+$4.1M +1.5M shares	$8.8M 3.2M shares
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	+$3.9M +1.4M shares	$5.9M 2.2M shares
VANGUARD GROUP INC Institution	+$2.6M +936.0K shares	$42.4M 15.5M shares
DIMENSIONAL FUND ADVISORS LP Long Only Manager	+$2.4M +884.6K shares	$4.8M 1.8M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$2.4M +868.5K shares	$8.7M 3.2M shares
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	+$2.2M +797.8K shares	$5.9M 2.1M shares

Biggest Sellers

Institution	Net Sold	Current Position
G GREAT POINT PARTNERS LLC Private Equity	−$7.2M −2.0M shares	Sold Off 0 shares
GOLDMAN SACHS GROUP INC Institution	−$5.9M −2.2M shares	$4.8M 1.8M shares
EAM Investors, LLC Long Only Manager	−$5.3M −1.5M shares	Sold Off 0 shares
Woodline Partners LP Hedge Fund•Long/Short	−$3.6M −1.0M shares	Sold Off 0 shares
MORGAN STANLEY RIA/Wealth	−$2.8M −1.0M shares	$11.8M 4.3M shares
JPMORGAN CHASE & CO Institution	−$1.8M −658.6K shares	$2.7M 994.2K shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	−$1.5M −542.6K shares	$1.8M 662.5K shares
N Nuveen, LLC Institution	−$1.1M −407.3K shares	$6.3M 2.3M shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	−$1.1M −289.5K shares	Sold Off 0 shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	−$816.3K −299.0K shares	$1.3M 492.3K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited AKBA in Q3 2025

New Positions: 15
New Value: $2.4M
Exited Positions: 18
Exited Value: $19.6M

New Positions

Institution	Position Value
Voleon Capital Management LP Hedge Fund•Quant	$578.1K 211.8K shares
F Freestone Grove Partners LP Hedge Fund•Multi-Strategy	$551.8K 202.1K shares
Round Rock Advisors, LLC RIA/Wealth	$426.9K 143.2K shares
Sontag Advisory, LLC RIA/Wealth	$191.1K 70.0K shares
K KLP KAPITALFORVALTNING AS Institution	$149.6K 54.8K shares
P Pale Fire Capital SE Institution	$137.1K 50.2K shares
S SHERBROOKE PARK ADVISERS LLC Hedge Fund•Quant	$77.5K 28.4K shares
Pictet Asset Management Holding SA Long Only Manager	$72.7K 26.6K shares
Parkwoods Wealth Partners, LLC RIA/Wealth	$54.6K 20.0K shares
Cambridge Investment Research Advisors, Inc. RIA/Wealth	$54.1K 19.8K shares

Exited Positions

Institution	Previous Position
G GREAT POINT PARTNERS LLC Private Equity	$7.2M 2.0M shares
EAM Investors, LLC Long Only Manager	$5.3M 1.5M shares
Woodline Partners LP Hedge Fund•Long/Short	$3.6M 1.0M shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	$1.1M 289.5K shares
L Longaeva Partners L.P. Institution	$697.8K 191.7K shares
C Cubist Systematic Strategies, LLC Institution	$614.2K 168.7K shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	$341.1K 93.7K shares
F FRED ALGER MANAGEMENT INC Long Only Manager	$243.9K 67.0K shares
Y Y-Intercept Ltd Institution	$111.6K 30.7K shares
H HSBC HOLDINGS PLC Institution	$104.5K 28.3K shares

Options Activity

Institutions with the largest Call and Put options positions in AKBA as of Q3 2025

Call Positions: 3
Call Value: $729.5K
Put Positions: 2
Put Value: $765.5K

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$329.2K 1.2K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$288.6K 1.1K contracts
J JANE STREET GROUP, LLC Institution	$111.7K 409.0 contracts

Put Positions

Institution	Position Value
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$628.4K 2.3K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$137.0K 502.0 contracts

Most Committed Institutions

Institutions with AKBA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
MPM Oncology Impact Management LP Institution	Christian Albrecht Wulf Von Schimmelmann Managing Partner	1.29% $7.9M	1.09% 2.9M shares	Q2 2025 Held for 5 months	$610.9M
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	Jonathan Bo-Shing Chu Founder	0.68% $6.7M	0.92% 2.5M shares	Q1 2025 Held for 8 months	$983.0M
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	Daniel J. Mack Managing Partner	0.34% $5.5M	0.75% 2.0M shares	Q1 2025 Held for 8 months	$1.6B
Orchard Capital Managment, LLC RIA/Wealth	Blake Elliott Harper Managing Partner	0.19% $146.1K	0.02% 53.5K shares	Q4 2020 Held for 4y 11m	$75.8M
Diametric Capital, LP Hedge Fund•Long/Short	David Richard Salvietti COO	0.09% $239.2K	0.03% 87.6K shares	Q4 2024 Held for 11 months	$264.8M
Round Rock Advisors, LLC RIA/Wealth	Bert Thomas Bowler Managing Partner	0.07% $426.9K	0.05% 143.2K shares	Q3 2025 Held for 2 months	$631.2M
Unified Investment Management RIA/Wealth	Ryan Malec Managing Partner	0.05% $49.1K	0.01% 18.0K shares	Q4 2024 Held for 11 months	$100.2M
E EntryPoint Capital, LLC Hedge Fund•Long/Short	Lawrence Edward Leibowitz CEO	0.05% $121.4K	0.02% 44.5K shares	Q2 2025 Held for 5 months	$258.4M
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	David Khabie-Zeitoune CEO	0.04% $498.1K	0.07% 182.4K shares	Q3 2025 Held for 2 months	$1.1B
S SHERBROOKE PARK ADVISERS LLC Hedge Fund•Quant	Kun Gao Founder	0.04% $77.5K	0.01% 28.4K shares	Q3 2025 Held for 2 months	$215.3M

Hedge Fund Spotlight

Discover hedge funds investing in AKBA

PANAGORA ASSET MANAGEMENT INC

Hedge Fund • Quant

Portfolio ManagerBryan David Belton

Portfolio Value: $24.8B
Positions: 1,146
Last Reported: Q3 2025

Sector Allocation

Position in Akebia Therapeutics

Market Value: $644.7K
Shares Held: 236.2K
Portfolio Weight: 0.00%
Owned Since: 2025-Q2

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