Paradigm Biocapital Advisors LP Portfolio Holdings
Q3 2025•33 long positions•$3.4B portfolio value
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Holding37 | Sector | Position↕ | Traded↕ | Ownership↕ | Shares Δ↕ | Shares Δ % | Market Cap↕ | Owned Since↕ |
|---|---|---|---|---|---|---|---|---|
Biotechnology Healthcare | $455.7M 13.48% | — | 7.31% 5.3M shares | — | — | $6.2B Mid Cap | Q2 2023 Held for 2y 5m | |
Biotechnology Healthcare | $411.8M 12.18% | +$8.6M Bought | 5.77% 4.4M shares | 4.3M → 4.4M +$8.6M | +2.14% | $7.1B Mid Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $381.7M 11.29% | — | 8.38% 4.6M shares | — | — | $4.6B Mid Cap | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $290.6M 8.6% | +$6.1M Bought | 3.33% 6.2M shares | 6.1M → 6.2M +$6.1M | +2.13% | $8.7B Mid Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $158.4M 4.69% | -$18.4M Sold | 6.31% 2.7M shares | 3.0M → 2.7M −$18.4M | -10.43% | $2.5B Mid Cap | Q4 2023 Held for 1y 11m | |
Biotechnology Healthcare | $136.3M 4.03% | +$14.8M Bought | 2.92% 3.8M shares | 3.4M → 3.8M +$14.8M | +12.21% | $4.7B Mid Cap | Q1 2024 Held for 1y 8m | |
Unknown Unknown | $132.8M 3.93% | +$132.8M New | — 1.6M shares | 0 → 1.6M +$132.8M | New | — — | Q3 2025 Held for 2 months | |
Unknown Unknown | $117.1M 3.46% | +$117.1M New | — 3.8M shares | 0 → 3.8M +$117.1M | New | — — | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $107.3M 3.18% | +$61.5M Bought | 4.6% 2.7M shares | 1.1M → 2.7M +$61.5M | +134.01% | $2.3B Mid Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $106.2M 3.14% | +$8.6M Bought | 2.71% 2.6M shares | 2.3M → 2.6M +$8.6M | +8.84% | $3.9B Mid Cap | Q3 2022 Held for 3y 2m | |
Biotechnology Healthcare | $100.1M 2.96% | +$450.7K Bought | 5.86% 6.2M shares | 6.1M → 6.2M +$450.7K | +0.45% | $1.7B Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $92.0M 2.72% | +$92.0M New | 3.79% 961.2K shares | 0 → 961.2K +$92.0M | New | $2.4B Mid Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $84.1M 2.49% | +$84.1M New | 9.11% 4.2M shares | 0 → 4.2M +$84.1M | New | $923.0M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $74.8M 2.21% | +$15.2M Bought | 2.09% 2.0M shares | 1.6M → 2.0M +$15.2M | +25.57% | $3.6B Mid Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $71.4M 2.11% | — | 4.86% 2.9M shares | — | — | $1.5B Small Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $66.5M 1.97% | +$293.7K Bought | 9.9% 6.8M shares | 6.8M → 6.8M +$293.7K | +0.44% | $671.9M Small Cap | Q1 2023 Held for 2y 8m | |
Biotechnology Healthcare | $60.5M 1.79% | +$22.4M Bought | 2.55% 1.5M shares | 958.6K → 1.5M +$22.4M | +58.74% | $2.4B Mid Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $56.3M 1.67% | -$2.9M Sold | 3.2% 2.6M shares | 2.7M → 2.6M −$2.9M | -4.82% | $1.8B Small Cap | Q4 2021 Held for 3y 11m | |
Biotechnology Healthcare | $51.6M 1.53% | +$10.3M Bought | 1.04% 1.7M shares | 1.4M → 1.7M +$10.3M | +24.99% | $5.0B Mid Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $50.0M 1.48% | -$30.0M Sold | 3.76% 1.1M shares | 1.7M → 1.1M −$30.0M | -37.48% | $1.3B Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $45.8M 1.36% | +$19.3M Bought | 2.85% 1.8M shares | 1.1M → 1.8M +$19.3M | +72.69% | $1.6B Small Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $45.3M 1.34% | -$103.3M Sold | 2.26% 3.2M shares | 10.4M → 3.2M −$103.3M | -69.51% | $2.0B Mid Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $40.9M 1.21% | +$899.7K Bought | 2.01% 3.5M shares | 3.4M → 3.5M +$899.7K | +2.25% | $2.0B Mid Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $35.5M 1.05% | -$14.6M Sold | 0.358% 684.3K shares | 965.8K → 684.3K −$14.6M | -29.15% | $9.9B Mid Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $29.6M 0.875% | +$3.6M Bought | 4.78% 13.6M shares | 11.9M → 13.6M +$3.6M | +13.88% | $618.4M Small Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $28.6M 0.845% | +$28.6M New | 2.91% 2.0M shares | 0 → 2.0M +$28.6M | New | $981.5M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $25.9M 0.767% | +$25.9M New | 2.77% 3.1M shares | 0 → 3.1M +$25.9M | New | $934.6M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $25.8M 0.764% | +$25.8M New | 1.78% 1.9M shares | 0 → 1.9M +$25.8M | New | $1.4B Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $24.6M 0.728% | -$6.8M Sold | 2.43% 1.5M shares | 1.9M → 1.5M −$6.8M | -21.56% | $1.0B Small Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $24.0M 0.711% | +$24.0M New | 1.33% 1.9M shares | 0 → 1.9M +$24.0M | New | $1.8B Small Cap | Q3 2025 Held for 2 months | |
Unknown Unknown | $21.6M 0.639% | +$21.6M New | 2.36% 1.9M shares | 0 → 1.9M +$21.6M | New | $917.1M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $16.4M 0.484% | -$63.7M Sold | 0.713% 247.7K shares | 1.2M → 247.7K −$63.7M | -79.54% | $2.3B Mid Cap | Q3 2023 Held for 2y 2m | |
Unknown Unknown | $10.4M 0.309% | +$10.4M New | — 372.9K shares | 0 → 372.9K +$10.4M | New | — — | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | - — | -$19.1M Sold | — - shares | 4.2M → 0 −$19.1M | Sold | — — | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | - — | -$16.9M Sold | — - shares | 3.1M → 0 −$16.9M | Sold | $661.2M Small Cap | Q2 2023 Held for 2y 5m | |
Unknown Unknown | - — | -$10.4M Sold | — - shares | 642.7K → 0 −$10.4M | Sold | $293.8M Micro Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | - — | -$41.5M Sold | — - shares | 878.3K → 0 −$41.5M | Sold | $2.9B Mid Cap | Q3 2024 Held for 1y 2m |
