Frazier Life Sciences Management, L.P. Portfolio Holdings
Q3 2025•47 long positions•$3.3B portfolio value
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Holding53 | Sector | Position↕ | Traded↕ | Ownership↕ | Shares Δ↕ | Shares Δ % | Market Cap↕ | Owned Since↕ |
|---|---|---|---|---|---|---|---|---|
Biotechnology Healthcare | $498.2M 14.93% | — | 13.53% 6.8M shares | — | — | $3.7B Mid Cap | Q1 2022 Held for 3y 8m | |
Biotechnology Healthcare | $475.0M 14.23% | +$2.7M Bought | 14.83% 16.7M shares | 16.6M → 16.7M +$2.7M | +0.57% | $3.2B Mid Cap | Q4 2022 Held for 2y 11m | |
Unknown Unknown | $361.1M 10.82% | — | — 3.4M shares | — | — | — — | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $199.7M 5.98% | +$2.3M Bought | 2.01% 3.8M shares | 3.8M → 3.8M +$2.3M | +1.18% | $9.9B Mid Cap | Q1 2023 Held for 2y 8m | |
Biotechnology Healthcare | $186.1M 5.58% | — | 8.24% 9.9M shares | — | — | $2.3B Mid Cap | Q1 2022 Held for 3y 8m | |
Biotechnology Healthcare | $146.7M 4.4% | — | 17.57% 12.5M shares | — | — | $835.0M Small Cap | Q1 2022 Held for 3y 8m | |
Biotechnology Healthcare | $121.5M 3.64% | — | 2.38% 688.5K shares | — | — | $5.1B Mid Cap | Q1 2022 Held for 3y 8m | |
Unknown Unknown | $118.4M 3.55% | -$25.9 Sold | 10.42% 4.6M shares | 4.6M → 4.6M −$25.9 | -0.0% | $1.1B Small Cap | Q1 2025 Held for 8 months | |
Unknown Unknown | $116.4M 3.49% | +$11.7M Bought | 14.88% 6.7M shares | 6.0M → 6.7M +$11.7M | +11.14% | $782.5M Small Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $95.1M 2.85% | -$14.3M Sold | 4.14% 1.4M shares | 1.7M → 1.4M −$14.3M | -13.07% | $2.3B Mid Cap | Q2 2023 Held for 2y 5m | |
Biotechnology Healthcare | $93.9M 2.81% | — | 8.42% 10.3M shares | — | — | $1.1B Small Cap | Q2 2022 Held for 3y 5m | |
Biotechnology Healthcare | $69.4M 2.08% | -$13.7M Sold | 2.77% 1.2M shares | 1.4M → 1.2M −$13.7M | -16.46% | $2.5B Mid Cap | Q1 2022 Held for 3y 8m | |
Biotechnology Healthcare | $61.4M 1.84% | +$1.9M Bought | 9.98% 5.0M shares | 4.9M → 5.0M +$1.9M | +3.11% | $615.4M Small Cap | Q1 2022 Held for 3y 8m | |
Unknown Unknown | $55.1M 1.65% | +$10.8M Bought | — 1.6M shares | 1.3M → 1.6M +$10.8M | +24.4% | — — | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $51.4M 1.54% | — | 2.2% 1.3M shares | — | — | $2.3B Mid Cap | Q3 2023 Held for 2y 2m | |
Biotechnology Healthcare | $49.6M 1.48% | — | 8.01% 22.7M shares | — | — | $618.4M Small Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $48.9M 1.47% | +$18.5M Bought | 0.744% 890.4K shares | 554.7K → 890.4K +$18.5M | +60.52% | $6.6B Mid Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $46.6M 1.4% | — | 0.534% 997.5K shares | — | — | $8.7B Mid Cap | Q1 2023 Held for 2y 8m | |
Unknown Unknown | $45.3M 1.36% | — | 6.53% 722.4K shares | — | — | $693.3M Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $40.9M 1.23% | — | 6.63% 11.5M shares | — | — | $617.0M Small Cap | Q3 2023 Held for 2y 2m | |
Biotechnology Healthcare | $34.4M 1.03% | +$15.3M Bought | 1.91% 2.7M shares | 1.5M → 2.7M +$15.3M | +80.49% | $1.8B Small Cap | Q1 2025 Held for 8 months | |
Unknown Unknown | $32.1M 0.962% | +$32.1M New | — 378.3K shares | 0 → 378.3K +$32.1M | New | — — | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $31.5M 0.944% | — | 8.21% 5.1M shares | — | — | $383.9M Small Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $29.6M 0.887% | — | 1.02% 983.7K shares | — | — | $2.9B Mid Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $29.4M 0.88% | — | 8.19% 4.4M shares | — | — | $358.6M Small Cap | Q3 2024 Held for 1y 2m | |
Unknown Unknown | $28.0M 0.838% | +$10.2M Bought | — 2.3M shares | 1.5M → 2.3M +$10.2M | +57.14% | — — | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $27.2M 0.816% | — | 0.428% 625.0K shares | — | — | $6.4B Mid Cap | Q1 2025 Held for 8 months | |
Unknown Unknown | $26.5M 0.794% | — | — 133.3K shares | — | — | — — | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $21.0M 0.63% | -$9.0M Sold | 0.424% 700.6K shares | 1.0M → 700.6K −$9.0M | -29.98% | $5.0B Mid Cap | Q3 2024 Held for 1y 2m | |
Unknown Unknown | $19.4M 0.583% | — | — 9.4M shares | — | — | — — | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $17.4M 0.522% | — | 0.459% 366.8K shares | — | — | $3.8B Mid Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $17.1M 0.512% | — | 0.365% 474.4K shares | — | — | $4.7B Mid Cap | Q1 2022 Held for 3y 8m | |
Drug Manufacturers - Specialty & Generic Healthcare | $16.2M 0.484% | +$1.2M Bought | 4.07% 2.6M shares | 2.4M → 2.6M +$1.2M | +8.01% | $397.2M Small Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $14.7M 0.441% | — | 3.43% 2.0M shares | — | — | $428.8M Small Cap | Q2 2024 Held for 1y 5m | |
Unknown Unknown | $14.0M 0.419% | — | — 384.8K shares | — | — | — — | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $13.1M 0.392% | +$13.1M Bought | 0.364% 613.8K shares | — | — | $3.6B Mid Cap | Q3 2022 Held for 3y 2m | |
Unknown Unknown | $12.2M 0.365% | -$3.1M Sold | 4.33% 1.4M shares | 1.8M → 1.4M −$3.1M | -20.25% | $281.6M Micro Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $11.7M 0.35% | +$11.7M New | 5.95% 456.2K shares | 0 → 456.2K +$11.7M | New | $196.4M Micro Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $9.4M 0.282% | +$4.6M Bought | 9.9% 2.1M shares | 1.1M → 2.1M +$4.6M | +94.29% | $95.1M Micro Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $9.4M 0.281% | -$14.6M Sold | 0.44% 392.1K shares | 1.0M → 392.1K −$14.6M | -60.87% | $2.1B Mid Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $8.6M 0.257% | — | — 500.3K shares | — | — | — — | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $7.9M 0.237% | +$7.9M New | 2.26% 1.2M shares | 0 → 1.2M +$7.9M | New | $349.6M Small Cap | Q3 2025 Held for 2 months | |
Unknown Unknown | $7.5M 0.226% | — | — 4.6M shares | — | — | — — | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $5.3M 0.16% | — | 5.02% 3.2M shares | — | — | $106.2M Micro Cap | Q3 2022 Held for 3y 2m | |
Unknown Unknown | $5.0M 0.151% | — | — 970.1K shares | — | — | — — | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $4.8M 0.144% | — | 1.74% 3.9M shares | — | — | $275.1M Micro Cap | Q1 2024 Held for 1y 8m | |
Unknown Unknown | $3.2M 0.097% | -$2.1M Sold | 1.63% 273.0K shares | 453.7K → 273.0K −$2.1M | -39.84% | $199.5M Micro Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | - — | -$10.8M Sold | — - shares | 1.1M → 0 −$10.8M | Sold | $893.9M Small Cap | Q2 2023 Held for 2y 5m | |
Biotechnology Healthcare | - — | -$2.2M Sold | — - shares | 6.0M → 0 −$2.2M | Sold | — — | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | - — | -$12.5M Sold | — - shares | 1.7M → 0 −$12.5M | Sold | $824.3M Small Cap | Q1 2022 Held for 3y 8m |
