RTW INVESTMENTS, LLC Portfolio Holdings
Q3 2025•72 long positions•$8.1B portfolio value
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Holding81 | Sector | Position↕ | Traded↕ | Ownership↕ | Shares Δ↕ | Shares Δ % | Market Cap↕ | Owned Since↕ |
|---|---|---|---|---|---|---|---|---|
Biotechnology Healthcare | $914.4M 11.34% | — | 8.94% 2.0M shares | — | — | $10.2B Large Cap | Q2 2023 Held for 2y 5m | |
Unknown Unknown | $496.7M 6.16% | — | — 673.5K shares | — | — | — — | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $495.5M 6.15% | +$76.4M Bought | 7.79% 11.4M shares | 9.6M → 11.4M +$76.4M | +18.23% | $6.4B Mid Cap | Q2 2020 Held for 5y 5m | |
Biotechnology Healthcare | $475.4M 5.9% | — | 9.75% 7.7M shares | — | — | $4.9B Mid Cap | Q4 2016 Held for 8y 11m | |
Biotechnology Healthcare | $444.2M 5.51% | — | 1.46% 3.1M shares | — | — | $30.4B Large Cap | Q2 2023 Held for 2y 5m | |
Biotechnology Healthcare | $382.4M 4.74% | — | 9.25% 5.8M shares | — | — | $4.1B Mid Cap | Q3 2019 Held for 6y 2m | |
Medical - Diagnostics & Research Healthcare | $321.9M 3.99% | -$95.6M Sold | 1.46% 2.0M shares | 2.6M → 2.0M −$95.6M | -22.89% | $22.1B Large Cap | Q3 2019 Held for 6y 2m | |
Biotechnology Healthcare | $260.1M 3.23% | — | 6.85% 5.5M shares | — | — | $3.8B Mid Cap | Q4 2023 Held for 1y 11m | |
Biotechnology Healthcare | $258.3M 3.2% | -$42.8M Sold | 7.18% 4.4M shares | 5.2M → 4.4M −$42.8M | -14.22% | $3.6B Mid Cap | Q3 2024 Held for 1y 2m | |
Medical - Devices Healthcare | $219.5M 2.72% | +$746.3K Bought | 2.22% 866.5K shares | 863.6K → 866.5K +$746.3K | +0.34% | $9.9B Mid Cap | Q3 2021 Held for 4y 2m | |
Medical - Diagnostics & Research Healthcare | $214.6M 2.66% | +$9.5M Bought | 3.66% 2.8M shares | 2.7M → 2.8M +$9.5M | +4.65% | $5.9B Mid Cap | Q4 2023 Held for 1y 11m | |
Biotechnology Healthcare | $190.7M 2.36% | -$186.0M Sold | 2.67% 2.0M shares | 4.0M → 2.0M −$186.0M | -49.38% | $7.1B Mid Cap | Q2 2023 Held for 2y 5m | |
Biotechnology Healthcare | $188.8M 2.34% | +$3.9M Bought | 7.53% 3.2M shares | 3.1M → 3.2M +$3.9M | +2.11% | $2.5B Mid Cap | Q4 2020 Held for 4y 11m | |
Medical - Devices Healthcare | $181.1M 2.25% | -$37.2M Sold | 0.128% 490.0K shares | 590.5K → 490.0K −$37.2M | -17.02% | $141.33B Large Cap | Q3 2023 Held for 2y 2m | |
Unknown Unknown | $176.9M 2.19% | — | — 4.9M shares | — | — | — — | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $152.5M 1.89% | -$39.5M Sold | 4.23% 7.1M shares | 9.0M → 7.1M −$39.5M | -20.58% | $3.6B Mid Cap | Q2 2022 Held for 3y 5m | |
Biotechnology Healthcare | $149.6M 1.85% | — | 2.27% 2.7M shares | — | — | $6.6B Mid Cap | Q3 2020 Held for 5y 2m | |
Drug Manufacturers - Specialty & Generic Healthcare | $149.1M 1.85% | — | 1.07% 1.1M shares | — | — | $13.9B Large Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $135.9M 1.69% | -$48.3M Sold | 2.24% 1.1M shares | 1.5M → 1.1M −$48.3M | -26.24% | $6.1B Mid Cap | Q1 2019 Held for 6y 8m | |
Biotechnology Healthcare | $120.4M 1.49% | — | 9.35% 5.1M shares | — | — | $1.3B Small Cap | Q2 2019 Held for 6y 5m | |
Biotechnology Healthcare | $107.8M 1.34% | — | 4.55% 2.7M shares | — | — | $2.4B Mid Cap | Q3 2023 Held for 2y 2m | |
Medical - Devices Healthcare | $106.1M 1.32% | +$192.7K Bought | 8.94% 2.6M shares | 2.6M → 2.6M +$192.7K | +0.18% | $1.2B Small Cap | Q3 2018 Held for 7y 2m | |
Medical - Instruments & Supplies Healthcare | $100.8M 1.25% | — | 1.26% 683.3K shares | — | — | $8.0B Mid Cap | Q3 2015 Held for 10y 2m | |
Biotechnology Healthcare | $98.0M 1.22% | +$46.6M Bought | 3.38% 3.3M shares | 1.7M → 3.3M +$46.6M | +90.83% | $2.9B Mid Cap | Q4 2021 Held for 3y 11m | |
Medical - Diagnostics & Research Healthcare | $92.5M 1.15% | +$39.0M Bought | 1.19% 1.5M shares | 856.5K → 1.5M +$39.0M | +72.92% | $7.8B Mid Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $90.7M 1.12% | — | 9.82% 4.5M shares | — | — | $923.0M Small Cap | Q3 2021 Held for 4y 2m | |
Medical - Instruments & Supplies Healthcare | $90.5M 1.12% | — | 0.056% 202.5K shares | — | — | $160.32B Large Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $79.6M 0.988% | +$416.2K Bought | 8.98% 5.6M shares | 5.5M → 5.6M +$416.2K | +0.53% | $887.0M Small Cap | Q2 2021 Held for 4y 5m | |
Biotechnology Healthcare | $79.6M 0.988% | -$2.2M Sold | 8.93% 24.4M shares | 25.0M → 24.4M −$2.2M | -2.67% | $892.0M Small Cap | Q3 2023 Held for 2y 2m | |
Unknown Unknown | $77.7M 0.963% | -$110.0M Sold | — 2.3M shares | 5.5M → 2.3M −$110.0M | -58.62% | — — | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $75.1M 0.931% | +$15.7M Bought | 7.25% 8.8M shares | 7.0M → 8.8M +$15.7M | +26.48% | $1.0B Small Cap | Q3 2020 Held for 5y 2m | |
Biotechnology Healthcare | $73.0M 0.905% | +$44.8M Bought | 8.72% 6.2M shares | 2.4M → 6.2M +$44.8M | +158.9% | $836.6M Small Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $68.5M 0.85% | — | 2.23% 1.7M shares | — | — | $3.1B Mid Cap | Q1 2024 Held for 1y 8m | |
Unknown Unknown | $65.6M 0.813% | — | 7.59% 3.3M shares | — | — | $863.8M Small Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $60.7M 0.753% | — | 6.0% 3.6M shares | — | — | $1.0B Small Cap | Q4 2023 Held for 1y 11m | |
Biotechnology Healthcare | $57.7M 0.715% | — | 16.39% 17.7M shares | — | — | $351.8M Small Cap | Q1 2018 Held for 7y 8m | |
Unknown Unknown | $55.6M 0.689% | +$18.5M Bought | — 2.3M shares | 1.5M → 2.3M +$18.5M | +49.8% | — — | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $50.2M 0.622% | -$90.3M Sold | 1.01% 1.7M shares | 4.7M → 1.7M −$90.3M | -64.28% | $5.0B Mid Cap | Q3 2023 Held for 2y 2m | |
Unknown Unknown | $49.9M 0.619% | +$2.8M Bought | — 8.7M shares | 8.2M → 8.7M +$2.8M | +5.9% | — — | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $49.8M 0.618% | +$49.8M New | 2.48% 3.5M shares | 0 → 3.5M +$49.8M | New | $2.0B Mid Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $47.9M 0.594% | +$10.4M Bought | 8.82% 5.4M shares | 4.3M → 5.4M +$10.4M | +27.63% | $543.4M Small Cap | Q1 2025 Held for 8 months | |
Medical - Diagnostics & Research Healthcare | $47.6M 0.591% | -$47.6M Sold | 0.224% 250.0K shares | 500.0K → 250.0K −$47.6M | -50.0% | $21.3B Large Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $40.2M 0.499% | — | 3.03% 863.4K shares | — | — | $1.3B Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $37.9M 0.47% | — | 8.89% 1.5M shares | — | — | $426.5M Small Cap | Q4 2024 Held for 11 months | |
Unknown Unknown | $37.4M 0.464% | — | 4.02% 1.9M shares | — | — | $930.4M Small Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $36.6M 0.453% | +$15.2M Bought | 2.03% 2.9M shares | 1.7M → 2.9M +$15.2M | +70.98% | $1.8B Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $36.3M 0.451% | +$16.9M Bought | 0.926% 872.4K shares | 467.0K → 872.4K +$16.9M | +86.81% | $3.9B Mid Cap | Q2 2025 Held for 5 months | |
Drug Manufacturers - Specialty & Generic Healthcare | $34.9M 0.433% | +$34.9M New | 5.17% 6.3M shares | 0 → 6.3M +$34.9M | New | $676.2M Small Cap | Q3 2025 Held for 2 months | |
Medical - Healthcare Information Services Healthcare | $29.6M 0.366% | -$17.5M Sold | 0.086% 393.5K shares | 626.0K → 393.5K −$17.5M | -37.14% | $34.3B Large Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $26.8M 0.332% | +$18.1M Bought | 8.19% 6.4M shares | 2.1M → 6.4M +$18.1M | +209.72% | $327.1M Small Cap | Q2 2024 Held for 1y 5m |
