RA CAPITAL MANAGEMENT, LLC Portfolio Holdings
Q3 2025•66 long positions•$8.1B portfolio value
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Holding77 | Sector | Position↕ | Traded↕ | Ownership↕ | Shares Δ↕ | Shares Δ % | Market Cap↕ | Owned Since↕ |
|---|---|---|---|---|---|---|---|---|
Unknown Unknown | $2.0B 25.39% | — | — 10.3M shares | — | — | — — | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $573.8M 7.13% | +$12.1M Bought | 8.55% 5.7M shares | 5.6M → 5.7M +$12.1M | +2.16% | $6.7B Mid Cap | Q2 2018 Held for 7y 5m | |
Biotechnology Healthcare | $431.0M 5.35% | — | 9.22% 12.0M shares | — | — | $4.7B Mid Cap | Q2 2020 Held for 5y 5m | |
Biotechnology Healthcare | $376.5M 4.68% | +$59.9M Bought | 5.92% 8.6M shares | 7.3M → 8.6M +$59.9M | +18.92% | $6.4B Mid Cap | Q3 2021 Held for 4y 2m | |
Biotechnology Healthcare | $322.3M 4.0% | — | 13.27% 3.4M shares | — | — | $2.4B Mid Cap | Q3 2024 Held for 1y 2m | |
Unknown Unknown | $307.2M 3.82% | — | 23.66% 10.4M shares | — | — | $1.3B Small Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $292.4M 3.63% | — | 13.39% 19.9M shares | — | — | $2.2B Mid Cap | Q4 2019 Held for 5y 11m | |
Biotechnology Healthcare | $288.4M 3.58% | — | 9.0% 10.1M shares | — | — | $3.2B Mid Cap | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $277.7M 3.45% | +$44.6M Bought | 9.44% 7.3M shares | 6.1M → 7.3M +$44.6M | +19.14% | $2.9B Mid Cap | Q1 2023 Held for 2y 8m | |
Biotechnology Healthcare | $273.5M 3.4% | — | 18.62% 11.2M shares | — | — | $1.5B Small Cap | Q2 2021 Held for 4y 5m | |
Biotechnology Healthcare | $249.3M 3.1% | — | 5.48% 3.0M shares | — | — | $4.6B Mid Cap | Q2 2024 Held for 1y 5m | |
Biotechnology Healthcare | $194.6M 2.42% | — | 14.65% 4.2M shares | — | — | $1.3B Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $170.7M 2.12% | — | 22.89% 12.2M shares | — | — | $745.6M Small Cap | Q3 2021 Held for 4y 2m | |
Biotechnology Healthcare | $169.1M 2.1% | +$8.5M Bought | 9.9% 10.4M shares | 9.9M → 10.4M +$8.5M | +5.31% | $1.7B Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $133.2M 1.65% | — | 11.43% 18.2M shares | — | — | $1.2B Small Cap | Q4 2015 Held for 9y 11m | |
Unknown Unknown | $131.6M 1.63% | — | 15.69% 7.0M shares | — | — | $838.6M Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $112.8M 1.4% | — | 7.2% 2.9M shares | — | — | $1.6B Small Cap | Q1 2024 Held for 1y 8m | |
Unknown Unknown | $109.8M 1.36% | — | 12.75% 7.0M shares | — | — | $861.5M Small Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $109.8M 1.36% | — | 12.38% 7.7M shares | — | — | $887.0M Small Cap | Q2 2021 Held for 4y 5m | |
Biotechnology Healthcare | $109.2M 1.36% | — | 10.99% 10.9M shares | — | — | $993.2M Small Cap | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $107.8M 1.34% | +$107.8M Bought | 1.73% 1.2M shares | — | — | $6.2B Mid Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $104.2M 1.29% | — | 4.54% 1.6M shares | — | — | $2.3B Mid Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $96.6M 1.2% | -$46.3 Sold | 28.92% 2.0M shares | 2.0M → 2.0M −$46.3 | -0.0% | $333.9M Small Cap | Q1 2021 Held for 4y 8m | |
Biotechnology Healthcare | $94.1M 1.17% | — | 18.91% 10.2M shares | — | — | $497.6M Small Cap | Q3 2022 Held for 3y 2m | |
Biotechnology Healthcare | $92.7M 1.15% | +$43.3M Bought | 29.19% 20.1M shares | 10.7M → 20.1M +$43.3M | +87.7% | $317.6M Small Cap | Q2 2022 Held for 3y 5m | |
Biotechnology Healthcare | $82.7M 1.03% | — | 9.46% 60.4M shares | — | — | $874.1M Small Cap | Q2 2020 Held for 5y 5m | |
Biotechnology Healthcare | $77.0M 0.957% | — | 8.63% 23.6M shares | — | — | $892.0M Small Cap | Q3 2023 Held for 2y 2m | |
Unknown Unknown | $63.2M 0.784% | — | 46.37% 31.4M shares | — | — | $136.2M Micro Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $43.5M 0.54% | +$1.1M Bought | 1.21% 1.2M shares | 1.1M → 1.2M +$1.1M | +2.67% | $3.6B Mid Cap | Q4 2024 Held for 11 months | |
Unknown Unknown | $42.5M 0.528% | — | — 1.5M shares | — | — | — — | Q4 2023 Held for 1y 11m | |
Biotechnology Healthcare | $41.8M 0.519% | — | 8.29% 511.2K shares | — | — | $503.9M Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $39.7M 0.493% | — | 9.77% 4.6M shares | — | — | $405.8M Small Cap | Q2 2023 Held for 2y 5m | |
Biotechnology Healthcare | $35.9M 0.445% | +$617.0 Bought | 7.46% 5.8M shares | 5.8M → 5.8M +$617.0 | +0.0% | $480.5M Small Cap | Q1 2018 Held for 7y 8m | |
Unknown Unknown | $35.4M 0.439% | — | 0.642% 675.5K shares | — | — | $5.5B Mid Cap | Q1 2025 Held for 8 months | |
Unknown Unknown | $28.3M 0.351% | — | 40.34% 9.9M shares | — | — | $70.1M Micro Cap | Q3 2024 Held for 1y 2m | |
Unknown Unknown | $28.1M 0.349% | +$28.1M New | 7.92% 1.8M shares | 0 → 1.8M +$28.1M | New | $354.4M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $27.5M 0.341% | — | 1.29% 1.2M shares | — | — | $2.1B Mid Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $26.1M 0.324% | +$26.1M New | 13.3% 1.0M shares | 0 → 1.0M +$26.1M | New | $196.4M Micro Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $25.5M 0.317% | — | 24.65% 14.9M shares | — | — | $103.6M Micro Cap | Q3 2021 Held for 4y 2m | |
Biotechnology Healthcare | $24.9M 0.31% | +$24.9M New | 7.57% 2.1M shares | 0 → 2.1M +$24.9M | New | $329.5M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $22.4M 0.278% | — | 15.21% 10.8M shares | — | — | $147.0M Micro Cap | Q3 2020 Held for 5y 2m | |
Biotechnology Healthcare | $19.5M 0.243% | — | 7.06% 6.0M shares | — | — | $276.5M Micro Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $18.8M 0.234% | +$18.8M Bought | 8.18% 17.1M shares | — | — | $230.3M Micro Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $16.8M 0.209% | — | 1.8% 2.0M shares | — | — | $934.6M Small Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $16.6M 0.206% | +$16.6M New | — 3.0M shares | 0 → 3.0M +$16.6M | New | — — | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $15.5M 0.192% | — | 1.07% 1.1M shares | — | — | $1.4B Small Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $15.1M 0.188% | — | 26.52% 8.3M shares | — | — | $56.9M Micro Cap | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $13.2M 0.163% | — | 14.61% 6.7M shares | — | — | $90.1M Micro Cap | Q2 2021 Held for 4y 5m | |
Biotechnology Healthcare | $11.7M 0.145% | +$11.7M Bought | 0.325% 200.0K shares | — | — | $3.6B Mid Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $9.2M 0.115% | — | 5.96% 3.6M shares | — | — | $155.1M Micro Cap | Q4 2024 Held for 11 months |
